A fibroblast is a type of biological cell typically with a spindle shape that synthesizes the extracellular matrix and collagen, produces the structural...
14 KB (1,676 words) - 08:20, 4 September 2024
Dermal fibroblasts are cells within the dermis layer of skin which are responsible for generating connective tissue and allowing the skin to recover from...
13 KB (1,527 words) - 00:49, 3 December 2023
Fibroblast growth factor 2 (FGF-2), also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by...
22 KB (2,698 words) - 17:05, 16 July 2024
Fibroblast activation protein alpha (FAP-alpha) also known as prolyl endopeptidase FAP is an enzyme that in humans is encoded by the FAP gene. Prolyl endopeptidase...
17 KB (2,086 words) - 09:37, 10 March 2024
Fibroblast growth factor receptor 3 (FGFR-3) is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster...
17 KB (1,845 words) - 01:41, 9 October 2024
The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of...
8 KB (827 words) - 22:08, 3 December 2023
Mouse Embryonic Fibroblasts (MEFs) are a type of fibroblast prepared from mouse embryo. MEFs show a spindle shape when cultured in vitro, a typical feature...
4 KB (463 words) - 11:37, 2 November 2024
Fibroblast-like synoviocytes (FLS) represent a specialised cell type located inside joints in the synovium. These cells play a crucial role in the pathogenesis...
7 KB (863 words) - 04:59, 9 December 2023
Fibroblast growth factor 1 (FGF-1) also known as acidic fibroblast growth factor (aFGF), is a growth factor and signaling protein encoded by the FGF1 gene...
20 KB (2,311 words) - 22:01, 16 July 2024
Fibroblast growth factors (FGF) are a family of cell signalling proteins produced by macrophages; they are involved in a wide variety of processes, most...
25 KB (3,124 words) - 21:38, 18 August 2024
cancer-associated fibroblast (CAF) (also known as tumour-associated fibroblast; carcinogenic- associated fibroblast; activated fibroblast) is a cell type...
31 KB (3,599 words) - 19:59, 30 June 2024
Fibroblast growth factor receptor 2 (FGFR-2) also known as CD332 (cluster of differentiation 332) is a protein that in humans is encoded by the FGFR2 gene...
14 KB (1,745 words) - 09:02, 15 July 2024
Fibroblast growth factor 23 (FGF-23) is a protein and member of the fibroblast growth factor (FGF) family which participates in the regulation of phosphate...
16 KB (1,840 words) - 07:12, 2 November 2024
macrophage and mast cells release fibroblast growth and chemotactic factors to activate fibroblasts from adjacent tissue. Fibroblasts at this stage loosen themselves...
104 KB (11,855 words) - 22:46, 15 November 2024
Fibroblast growth factor 21 (FGF-21) is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast...
24 KB (3,038 words) - 18:36, 14 July 2024
(EPO) Fibroblast growth factor (FGF) Fibroblast growth factor 1(FGF1) Fibroblast growth factor 2(FGF2) Fibroblast growth factor 3(FGF3) Fibroblast growth...
10 KB (1,131 words) - 19:14, 31 March 2024
Fibroblast growth factor receptor 1 (FGFR-1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome...
44 KB (5,003 words) - 07:11, 15 October 2024
thumbs and big toes. Pfeiffer syndrome is caused by mutations in the fibroblast growth factor receptors FGFR1 and FGFR2. The syndrome is grouped into...
14 KB (1,444 words) - 19:55, 23 August 2024
Scar (section Fibroblasts)
shedding or injury, can scar. Prolonged inflammation, as well as the fibroblast proliferation, can occur. Redness that often follows an injury to the...
52 KB (5,791 words) - 14:27, 2 November 2024
protein synthesis. The term fibrocyte contrasts with the term fibroblast. Fibroblasts are activated connective tissue cells characterized by synthesis...
3 KB (379 words) - 22:37, 2 August 2024
FGF18 (redirect from Fibroblast growth factor 18)
Fibroblast growth factor 18 (FGF-18) is a protein that is encoded by the FGF18 gene in humans. The protein was first discovered in 1998, when two newly-identified...
20 KB (2,154 words) - 17:29, 16 July 2024
Effector cell (section Fibroblast as effector cells)
reconstructs the Central nervous system after a bone marrow transplant Fibroblast, a cell that is most commonly found within connective tissue Mast cell...
7 KB (891 words) - 05:58, 27 November 2022
FGF5 (redirect from Fibroblast growth factor 5)
Fibroblast growth factor 5 is a protein that in humans is encoded by the FGF5 gene. The majority of FGF family members are glycosaminoglycan binding proteins...
19 KB (2,251 words) - 15:12, 25 April 2024
Sprifermin (redirect from Recombinant human fibroblast growth factor 18)
Sprifermin (INN) (developmental code name AS-902330), is a recombinant human fibroblast growth factor 18 (rhFGF18) analog, which is under development by TrialSpark...
10 KB (532 words) - 01:58, 22 July 2024
synovial cells (type A) and also type B cells, which are also known as fibroblast-like synoviocytes (FLS). Type A cells maintain the synovial fluid by removing...
11 KB (1,315 words) - 00:51, 30 April 2024
Fibroblast growth factor 8 (FGF-8) is a protein that in humans is encoded by the FGF8 gene. The protein encoded by this gene is a member of the fibroblast...
17 KB (2,175 words) - 03:31, 24 December 2023
Cardiac muscle (section Fibroblasts)
cells are surrounded by an extracellular matrix produced by supporting fibroblast cells. Specialised modified cardiomyocytes known as pacemaker cells, set...
42 KB (5,130 words) - 05:03, 14 August 2024
type are they dominant. Reticular fibers are synthesized by special fibroblasts called reticular cells. The fibers are thin branching structures. Reticular...
3 KB (369 words) - 23:39, 13 September 2024
cell phenotype that was first described as being in a state between a fibroblast and a smooth muscle cell. Myofibroblasts are contractile web-like fusiform...
10 KB (1,066 words) - 15:56, 30 July 2024
erosion of the joint surface causing deformity and loss of function. The fibroblast-like synoviocytes (FLS), highly specialized mesenchymal cells found in...
149 KB (16,153 words) - 04:13, 11 November 2024