G proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as molecular switches inside cells, and are involved...
24 KB (2,754 words) - 17:11, 18 October 2024
G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors...
82 KB (9,384 words) - 16:34, 5 September 2024
Protein A/G is a recombinant fusion protein that combines IgG binding domains of both protein A and protein G. Protein A/G contains four Fc binding domains...
3 KB (359 words) - 16:13, 20 December 2023
Heterotrimeric G protein, also sometimes referred to as the "large" G proteins (as opposed to the subclass of smaller, monomeric small GTPases) are membrane-associated...
13 KB (1,237 words) - 18:10, 26 April 2024
Respiratory syncytial virus (redirect from Respiratory syncytial virus F protein)
and G proteins, F fusion occurs independently of G. F protein exists in multiple conformational forms. In the prefusion state (PreF), the protein exists...
97 KB (9,598 words) - 19:56, 26 October 2024
of proteins is a member of the Ras superfamily of small G proteins. Approximately 70 types of Rabs have now been identified in humans. Rab proteins generally...
12 KB (1,327 words) - 14:51, 31 July 2024
Protein G is an immunoglobulin-binding protein expressed in group C and G streptococcal bacteria much like protein A but with differing binding specificities...
5 KB (549 words) - 14:43, 15 May 2024
Regulators of G protein signaling (RGS) are protein structural domains or the proteins that contain these domains, that function to activate the GTPase...
9 KB (998 words) - 13:59, 22 June 2024
ligand-stimulated G protein-coupled receptors (GPCRs). GPCRs in turn release activated G-protein βγ- subunits (Gβγ) from inactive heterotrimeric G protein complexes...
9 KB (804 words) - 23:15, 23 May 2023
Cell signaling (redirect from Signaling protein)
including ions (e.g. Na+, K+, Ca++, etc.), lipids (e.g. steroid, prostaglandin), peptides (e.g. insulin, ACTH), carbohydrates, glycosylated proteins (proteoglycans)...
62 KB (6,781 words) - 23:57, 21 August 2024
G protein-coupled receptor kinases (GPCRKs, GRKs) are a family of protein kinases within the AGC (protein kinase A, protein kinase G, protein kinase C)...
18 KB (2,053 words) - 10:12, 12 August 2024
G protein-gated ion channels are a family of transmembrane ion channels in neurons and atrial myocytes that are directly gated by G proteins. Generally...
30 KB (3,706 words) - 21:03, 30 December 2023
Receptor (biochemistry) (redirect from Receptor protein)
Receptor proteins can be classified by their location. Cell surface receptors, also known as transmembrane receptors, include ligand-gated ion channels, G protein-coupled...
26 KB (2,672 words) - 14:14, 22 July 2024
GTPase (section Heterotrimeric G proteins)
binding and hydrolysis takes place in the highly conserved P-loop "G domain", a protein domain common to many GTPases. GTPases function as molecular switches...
20 KB (2,306 words) - 18:17, 15 July 2024
membrane protein (IMP) is a type of membrane protein that is permanently attached to the biological membrane. All transmembrane proteins can be classified...
9 KB (1,035 words) - 19:59, 25 January 2024
intracellular heterotrimeric G protein complex by protein domain dynamics. The Gs alpha subunit of the stimulated G protein complex exchanges GDP for GTP...
27 KB (2,665 words) - 17:03, 6 April 2024
homodimeric protein NEMO. Some proteins contain specialized domains to ensure dimerization (dimerization domains) and specificity. The G protein-coupled cannabinoid...
6 KB (653 words) - 16:09, 6 October 2024
Protein quaternary structure is the fourth (and highest) classification level of protein structure. Protein quaternary structure refers to the structure...
21 KB (2,342 words) - 16:59, 19 May 2024
Signal transduction (redirect from Intracellular signaling peptides and proteins)
homology domains of proteins such as the kinase protein AKT. G protein–coupled receptors (GPCRs) are a family of integral transmembrane proteins that possess...
63 KB (7,609 words) - 04:41, 21 June 2024
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions...
103 KB (11,472 words) - 15:03, 19 October 2024
The GPCR can then activate an associated G-protein by exchanging its bound GDP for a GTP. The G-protein's α subunit, together with the bound GTP, can...
16 KB (1,590 words) - 01:49, 26 October 2023
have been identified, as have drugs at ligand gated ion channels and at G protein-coupled receptors. An example of a receptor site that possesses basal...
11 KB (1,120 words) - 05:43, 29 February 2024
Prize in Physiology or Medicine "for their discovery of G-proteins and the role of these proteins in signal transduction in cells." Gilman was the son of...
35 KB (3,668 words) - 23:17, 12 October 2024
Dimerization (section G protein-coupled receptors)
required to make the functional protein. As the largest and most diverse family of receptors within the human genome, G protein-coupled receptors (GPCR) have...
12 KB (1,298 words) - 11:51, 19 October 2024
Fanconi anemia (redirect from Fanconi anemia complementation group g protein)
studies have shown that eight of these proteins, FANCA, -B, -C, -E, -F, -G, -L and -M, assemble to form a core protein complex in the nucleus. According to...
37 KB (4,138 words) - 03:05, 19 October 2024
ADRB1, can refer to either the protein-encoding gene (gene ADRB1) or one of the four adrenergic receptors. It is a G-protein coupled receptor associated...
31 KB (3,742 words) - 16:12, 25 October 2024
s ( g ) P r o t e i n i n t a k e ( g ) {\displaystyle PER\,={\frac {Gain\ in\ body\ mass(g)}{Protein\ intake(g)}}} Protein (nutrient) Protein Digestibility...
3 KB (298 words) - 11:21, 28 March 2022
protein A, other immunoglobulin-binding bacterial proteins such as protein G, protein A/G and protein L are all commonly used to purify, immobilize or...
17 KB (1,860 words) - 10:05, 20 May 2024
GTPase-activating proteins or GTPase-accelerating proteins (GAPs) are a family of regulatory proteins whose members can bind to activated G proteins and stimulate...
16 KB (2,237 words) - 20:38, 22 July 2024
A G protein-coupled receptors (GPCRs) via direct binding, and enhance their selectivity toward certain G proteins. PIP2 has been shown to recruit G protein-coupled...
21 KB (2,099 words) - 13:43, 21 August 2024