GMP reductase EC 1.7.1.7 (Guanosine 5'-monophosphate oxidoreductase ) is an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination...

dehydrogenase (IMPDH) converts IMP into XMP GMP synthase converts XMP into GMP GMP reductase converts GMP back into IMP adenylosuccinate synthase converts...

biology, the IMPDH/GMPR family of enzymes includes IMP dehydrogenase and GMP reductase. These enzymes are involved in purine metabolism. These enzymes adopt...

DMSO reductase is a molybdenum-containing enzyme that catalyzes reduction of dimethyl sulfoxide (DMSO) to dimethyl sulfide (DMS). This enzyme serves as...

proteins with sulfite- and nitrate reductase domains, proteins in the major facilitator superfamily and cyclic di-GMP-specific phosphodiesterases of the...

monophosphate (IMP). IMP is then converted to either a precursor to AMP or GMP. Once AMP or GMP are formed, they can be phosphorylated by ATP to their diphosphate...

EC 1.7.1.4: nitrite reductase (NAD(P)H) EC 1.7.1.5: hyponitrite reductase EC 1.7.1.6: azobenzene reductase EC 1.7.1.7: GMP reductase EC 1.7.1.8: deleted...

cGMP-dependent protein kinase or protein kinase G (PKG) is a serine/threonine-specific protein kinase that is activated by cGMP. It phosphorylates a number...

Nitrate reductases are molybdoenzymes that reduce nitrate (NO− 3) to nitrite (NO− 2). This reaction is critical for the production of protein in most crop...

molecule: cyclic di-GMP. At low cyclic di-GMP concentration, P. aeruginosa has a free-swimming mode of life. But when cyclic di-GMP levels increase, P...

as a powerful folate metabolism inhibitor by inhibiting dihydrofolate reductase, with hypoxanthine (a purine derivative) and thymidine (a deoxynucleoside)...

large-scale cultures and have great viability, which is why they are ideal for GMP protein production. Also, CHO cells are tolerant to variations in parameters...

XMP is then converted into GMP by using the hydrolysis of 1 ATP and the conversion of glutamine to glutamate. AMP and GMP can then be converted into ATP...

dinitrogenase reductase MeSH D08.811.682.647.550 – molybdoferredoxin MeSH D08.811.682.655.249 – gmp reductase MeSH D08.811.682.655.500 – nitrate reductases MeSH D08...

causing soluble guanylyl cyclase activation with a resultant rise in cyclic GMP, and the activation of gamma globin gene expression and subsequent gamma...

PMC 123083. PMID 12048242. Poetsch A, Molday LL, Molday RS (2002). "The cGMP-gated channel and related glutamic acid-rich proteins interact with peripherin-2...

the proteins glutamine-hydrolyzing GMP synthase, type I methionyl aminopeptidase, ribonucleoside-diphosphate reductase subunit alpha, translation initiation...

Deoxyribonucleotides, formed by reducing ribonucleotides with the enzyme ribonucleotide reductase (RNR), are essential building blocks for DNA. There are several differences...

Braden TM, Calvin JR, Campbell BM, Changi SM, et al. (2021). "Kilogram-Scale GMP Manufacture of Tirzepatide Using a Hybrid SPPS/LPPS Approach with Continuous...

cyclic-guanosine 3',5'-monophosphate (cGMP). The elevation of intracellular cGMP results in relaxation by the activation of cGMP-dependent protein kinase, which...

the MTX-PROTAC versortrexate (VSTX) selectively degrades dihydrofolate reductase (DHFR), the primary target of MTX. Methotrexate was originally developed...

AMPK also phosphorylates and inactivates 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), a key enzyme in cholesterol synthesis. HMGR converts...

the steps in the biosynthesis of inosine monophosphate, the precursor to GMP and AMP. Methylenetetrahydrofolate donates the C1 center required for the...

cyclase, which induces smooth muscle relaxation by: Increased intracellular cGMP, which inhibits calcium entry into the cell, and decreases intracellular...

(2003). "Coordinate expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-directed hydrolase, DCS-1". J. Biol. Chem. 278 (40): 39051–8...

and fungi. The majority of antifolates work by inhibiting dihydrofolate reductase (DHFR). Methotrexate Pemetrexed Raltitrexed Pralatrexate Many are primarily...

Finally, Cinnamoyl-CoA is reduced by NADPH catalyzed by CCR (cinnamoyl-CoA reductase) to form cinnamaldehyde. Several methods of laboratory synthesis exist...

Eventually the gas is converted to sulfite in the mitochondria by thiosulfate reductase, and the sulfite is further oxidized to thiosulfate and sulfate by sulfite...

EURL homolog CBR1: encoding enzyme carbonyl reductase [NADPH] 1 CBR3: encoding enzyme carbonyl reductase [NADPH] 3 CBS: encoding enzyme cystathionine-beta-synthase...

Topical corticosteroids (e.g., hydrocortisone) Alopecia treatments 5α-Reductase inhibitors Alfatradiol Dutasteride Finasteride Saw palmetto extract Antiandrogens...