Human leukocyte antigen (HLA) B27 (subtypes B*2701-2759) is a class I surface molecule encoded by the B locus in the major histocompatibility complex (MHC)...

spondylitis: A version of the HLA-B gene called HLA-B27 increases the risk of developing ankylosing spondylitis. It is uncertain how HLA-B27 causes this increased...

affected in the UK have a specific human leukocyte antigen known as the HLA-B27 antigen. The underlying mechanism is believed to be autoimmune or autoinflammatory...

HLA-B27, which has important features: HLA-B27 AAU can be associated with ocular inflammation alone or in association with systemic disease. HLA-B27 AAU...

B27 may refer to: Bundesstraße 27, a German road HLA-B27, an HLA B serotype Mark 27 nuclear bomb Martin XB-27, a proposed experimental American aircraft...

genitourinary and respiratory infections, and genetic variables. HLA-B27, a polymorphic form of the HLA-B molecule, is found in up to 95% of those who are European...

(e.g., HLA-B27 or, shortened, B27). A parallel system that allowed more refined definition of alleles was developed. In this system, an "HLA" is used...

site has already improved). Reactive arthritis is an RF-seronegative, HLA-B27-linked arthritis often precipitated by genitourinary or gastrointestinal...

of autoimmune diseases more than others. HLA-B27 is an example. It is unclear how exactly having the HLA-B27 tissue type increases the risk of ankylosing...

genetic make-up. That is, persons who have the human leukocyte antigen B27 (HLA-B27) are most susceptible. Most often, the symptoms of reactive arthritis...

where the Achilles tendon attaches to the calcaneus. It is associated with HLA B27 arthropathies, such as ankylosing spondylitis, psoriatic arthritis, and...

erythrocyte sedimentation rate, anti-nuclear antibodies, rheumatoid factor, HLA-B27, uric acid, or Lyme disease antibodies may also be obtained. Neurological...

patients with the ankylosing spondylitis variant test positive for the HLA-B27 biomarker, but not everyone with this biomarker will develop disease. Some...

SUMO4 gene variant is involved, and symptoms appear to be milder when HLA-B27 is present. Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.;...

development of AIDS. Certain HLA allotypes have been found to determine the progression of HIV to AIDS; an example is the HLA-B57 and HLA-B27 alleles, which have...

where tendons or ligaments insert into the bone. It is associated with HLA B27 arthropathies such as ankylosing spondylitis, psoriatic arthritis, and...

leading to deposition of immune complexes. There is an association with the HLA-B27 histocompatibility antigen, which is present in 65% of patients with erythema...

certain bacterial infections. Reactive arthritis is highly associated with HLA-B27. Conjunctivitis is associated with the autoimmune disease relapsing polychondritis...

conducted at King's College, London has implicated molecular mimicry between HLA-B27 and two Klebsiella surface molecules as the cause of ankylosing spondylitis...

caused by HLA-B27, disturbing balance of important (IL-10 and TNF) signaling proteins. At least some disturbances are reliant on correct HLA-B27 folding...

SUMO4 gene variant is involved, and symptoms appear to be milder when HLA-B27 is present. At the current time, a similar infectious origin has not yet...

anti-inflammatory activity of dietary fiber (Plantago ovata seeds) in HLA-B27 transgenic rats". Clinical Nutrition. 22 (5): 463–71. doi:10.1016/S0261-5614(03)00045-1...

and has genetic risk factor overlap with ankylosing spondylitis with HLA-B27, IL-23R77, and IL-1, however, as of 2016, immunopathogenesis is unclear...

presence of specific immune markers which may include anti-nuclear antibody, HLA-B27, rheumatoid factor and anti–citrullinated protein antibody. These serological...

Balfour (June 1999). "Differential Induction of Colitis and Gastritis in HLA-B27 Transgenic Rats Selectively Colonized with Bacteroides vulgatus or Escherichia...

alloantigen). Nevertheless, the β2 microglobulin gene is outside of the MHC (HLA) locus, on a different chromosome. An additional function is association...

plant molecular pathology at the University of Queensland and a PhD titled HLA-B27 and related genes in the aetiopathogenesis of ankylosing spondylitis at...

herniated disc; spinal stenosis; or compression fracture Inflammatory – HLA-B27 associated arthritis including ankylosing spondylitis, reactive arthritis...

children, two HLA-B27 alleles were found associated with disease, B*2702, B*2705. The study showed also B*0702 in cooperation with B*27, the HLA-B*07/B*27...

of the HLA System revised the nomenclature for HLAs. Before this revision, HLA-A*02 was also referred to as HLA-A2, HLA-A02, and HLA-A*2. HLA-A*02 is...