receptor-associated kinase-like 2 is an enzyme that in humans is encoded by the IRAK2 gene. IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two...
6 KB (704 words) - 21:45, 4 April 2024
structures which are similar to those of IRAK1, IRAK2, IRAK3 and Pelle. IRAK4 is unique compared to IRAK1, IRAK2 and IRAKM in that it functions upstream of...
20 KB (2,536 words) - 12:44, 26 September 2024
MyD88, a member of the TIR family. MyD88 then recruits IRAK4, IRAK1 and IRAK2. IRAK kinases then phosphorylate and activate the protein TRAF6, which in...
61 KB (6,771 words) - 07:38, 8 October 2024
dendritic cells. MyD88 attracts the IRAK4 molecule, IRAK4 recruits IRAK1 and IRAK2 to form a signaling complex. The signaling complex reacts with TRAF6 which...
43 KB (5,173 words) - 21:02, 10 August 2024
Waldenström's macroglobulinemia. Myd88 has been shown to interact with: IRAK1 IRAK2 Interleukin 1 receptor, type I RAC1 TLR 4 Various single nucleotide polymorphisms...
20 KB (2,250 words) - 15:55, 30 July 2024
Dancon/Irak1 (May 2003 – October 2003) – Colonel Niels H. Bundsgaard Dancon/Irak2 (October 2003 – 13 February 2004) – Colonel Henrik Højris Friis Dancon/Irak3...
13 KB (1,591 words) - 04:45, 29 February 2024
Q12912 7766 IRAK1 HGNC:6112 P51617 7767 IRAK1BP1 HGNC:17368 Q5VVH5 7768 IRAK2 HGNC:6113 O43187 7769 IRAK3 HGNC:17020 Q9Y616 7770 IRAK4 HGNC:17967 Q9NWZ3...
277 KB (17 words) - 18:41, 6 October 2024
(IRAK) 4. Phosphorylation of IRAK4 is followed by phosphorylation of IRAK1, IRAK2 and tumor necrosis factor receptor-associated factor (TRAF) 6. TRAF6 is...
50 KB (6,093 words) - 20:45, 19 November 2024
kinases. Four IRAK family members have been described in humans: IRAK1, IRAK2, IRAKM, and IRAK4. Two are active kinases, IRAK-1 and IRAK-4, and two are...
30 KB (3,637 words) - 08:49, 24 August 2024
"Equal Eye" - 4.12 "Slovakian Hell" - 4.44 "March of the crying" - 3.20 "Irak2" - 4.47 "To The Sky" - 4.47 "Eternal" - 3.03 "Lamandier" - 1.35 "Tschuesch...
3 KB (329 words) - 04:17, 20 January 2022
HIPK4 ; HUNK ; ICK ; IGF1R ; IKBKB ; IKBKE ; ILK ; INSR ; INSRR ; IRAK1 ; IRAK2 ; IRAK3 ; IRAK4 ; ITK ; JAK1 ; JAK2 ; JAK3 ; KALRN ; KDR ; KIT ; KSR1 ;...
17 KB (1,562 words) - 23:49, 23 December 2024
has been shown to interact with: ASK1, CD40, FHL2, HSPB2, IKBKG, IRAK1, IRAK2, TAB1, MAP3K7IP2, MAP3K7 PPP4C, RANK, SDCBP, SIGIRR, Sequestosome 1, TAX1BP1...
20 KB (2,350 words) - 01:06, 3 October 2024
RIG-I-Dependent Type I IFN Production in Macrophages by Targeting TRAF6, IRAK1, and IRAK2". Journal of Immunology. 183 (3): 2150–2158. doi:10.4049/jimmunol.0900707...
12 KB (964 words) - 22:20, 1 September 2024
TLR9 TLR10 TLR11 TLR12 TLR13 Other receptors CD14 LBP MD2 Downstream signalling IRAK1 IRAK2 IRAK3 IRAK4 IRF3 MAP3K7 MYD88 TAB1 TICAM1 TIRAP TOLLIP TRAF6...
38 KB (2,656 words) - 20:26, 6 November 2024
regulates neuroimmune-related Interleukin-1R associated kinases IRAK1 and IRAK2 expression, in human AD brain, while other studies have shown upregulation...
113 KB (13,392 words) - 02:52, 24 May 2024