lumacaftor/ivacaftor, tezacaftor/ivacaftor, and elexacaftor/tezacaftor/ivacaftor which are used to treat people with cystic fibrosis. Ivacaftor was developed...
34 KB (3,178 words) - 22:52, 20 December 2024
Elexacaftor/tezacaftor/ivacaftor, sold under the brand names Trikafta and Kaftrio, is a fixed-dose combination medication used to treat cystic fibrosis...
38 KB (3,107 words) - 08:02, 24 June 2024
Lumacaftor/ivacaftor, sold under the brand name Orkambi among others, is a combination of lumacaftor and ivacaftor used to treat people with cystic fibrosis...
15 KB (1,370 words) - 07:39, 4 July 2024
Reimbursement of ORKAMBI® (lumacaftor/ivacaftor) and SYMKEVI® (tezacaftor/ivacaftor) in Combination With KALYDECO® (ivacaftor)". www.businesswire.com. 21 October...
40 KB (3,930 words) - 20:40, 14 November 2024
available in a single pill with ivacaftor and tezacaftor; the fixed-dose combination, elexacaftor/tezacaftor/ivacaftor (brand name Trikafta), is used to...
7 KB (286 words) - 07:16, 24 November 2024
cell surface. It is available in a single pill with ivacaftor; the combination, lumacaftor/ivacaftor (brand name Orkambi), is used to treat people with...
5 KB (179 words) - 22:52, 20 December 2024
fixed-dose combination medications. The combination of tezacaftor with ivacaftor (brand name Symdeko) was approved for medical use in the United States...
14 KB (985 words) - 02:18, 24 December 2024
R07AX01 Nitric oxide R07AX02 Ivacaftor R07AX30 Ivacaftor and lumacaftor R07AX31 Ivacaftor and tezacaftor R07AX32 Ivacaftor, tezacaftor and elexacaftor...
1 KB (242 words) - 00:23, 24 December 2024
cystic fibrosis. Ivacaftor is a medication taken by mouth for the treatment of CF due to a number of specific mutations responsive to ivacaftor-induced CFTR...
162 KB (18,244 words) - 00:18, 26 December 2024
(COPD) and cystic fibrosis. The drug is being developed by Novartis. Like ivacaftor (which is marketed as Kalydeco), icenticaftor functions by acting as a...
6 KB (241 words) - 16:38, 7 June 2024
Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
117 KB (11,215 words) - 09:14, 23 December 2024
Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
107 KB (10,914 words) - 15:01, 26 December 2024
Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
182 KB (19,658 words) - 01:43, 10 December 2024
Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
93 KB (8,733 words) - 03:33, 16 December 2024
Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
45 KB (4,743 words) - 20:54, 22 December 2024
Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
83 KB (8,671 words) - 07:55, 25 December 2024
Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
83 KB (7,714 words) - 23:28, 9 December 2024
but the arrangement with CFF continued and resulted in the discovery of ivacaftor in 2005 and the approval of that drug in 2012.[citation needed] Aurora...
16 KB (1,650 words) - 02:43, 9 October 2024
Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
29 KB (2,711 words) - 03:05, 3 December 2024
Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
96 KB (9,528 words) - 07:35, 26 December 2024
Pharmaceuticals discovered ivacaftor, a small-molecule potentiator that increases the probability that mutated CFTR gates will open. Ivacaftor was approved by the...
19 KB (1,496 words) - 21:41, 21 June 2024
Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
51 KB (4,686 words) - 22:41, 9 December 2024
PMID 19436518. Davis, Pamela B.; Yasothan, Uma; Kirkpatrick, Peter (2012-04-30). "Ivacaftor". Nature Reviews Drug Discovery. 11 (5): 349–350. doi:10.1038/nrd3723...
42 KB (4,008 words) - 14:22, 25 October 2024
Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
61 KB (5,414 words) - 23:03, 25 December 2024
Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
31 KB (3,424 words) - 21:36, 22 December 2024
been a drug target in efforts to find treatments for related conditions. Ivacaftor (brand name Kalydeco, developed as VX-770) is a medication approved by...
61 KB (6,506 words) - 02:55, 24 December 2024
Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
64 KB (5,735 words) - 22:58, 22 December 2024
Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
97 KB (10,572 words) - 06:06, 10 December 2024
Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
13 KB (1,082 words) - 16:34, 19 December 2024
Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
28 KB (2,367 words) - 19:27, 7 December 2024