Lovastatin, sold under the brand name Mevacor among others, is a statin medication, to treat high blood cholesterol and reduce the risk of cardiovascular...
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yeast rice. Chemical analysis soon showed that lovastatin and monacolin K were identical. Lovastatin became the patented prescription drug Mevacor. Red...
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of producing 70 mg lovastatin per kilogram of substrate. The red yeast rice fungus, Monascus purpureus, can synthesize lovastatin, mevastatin, and the...
19 KB (1,718 words) - 19:43, 22 April 2024
various forms of statins, some of which include atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, and simvastatin. Combination...
134 KB (13,062 words) - 13:35, 14 October 2024
In enzymology, lovastatin nonaketide synthase (EC 2.3.1.161) is an enzyme that catalyzes the chemical reaction acetyl-CoA + 8 malonyl-CoA + 11 NADPH +...
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like xylanase. It was also the initial source for the drug mevinolin (lovastatin), a drug for lowering serum cholesterol. Aspergillus terreus can cause...
28 KB (3,074 words) - 00:09, 11 January 2024
Niacin/lovastatin (trade names Advicor) was a drug combination used for the treatment of dyslipidemia. It was a combination of the lipid-modifying drug/vitamin...
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"Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin". Clinical Pharmacokinetics. 47 (7): 463–474...
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of SHP's red yeast rice supplements contained significant amounts of lovastatin, the active ingredient in Mevacor and its generic counterparts. The FDA...
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characteristic side effects for statins, can also occur. Contrary to lovastatin, simvastatin and atorvastatin, fluvastatin has no relevant interactions...
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and colleagues isolated lovastatin from a strain of the fungus Aspergillus terreus. While developing and researching lovastatin, Merck scientists synthetically...
33 KB (3,284 words) - 00:33, 1 September 2024
HMG-CoA reductase inhibitors including simvastatin, simvastatin acid, lovastatin, fluvastatin, atorvastatin and cerivastatin inhibit the metabolism of...
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high‐risk patients. Atorvastatin, fluvastatin, lovastatin, and pravastatin are alternatives fluvastatin, lovastatin, pravastatin, and simvastatin are alternatives...
67 KB (4,835 words) - 06:05, 31 October 2024
USDA and by Pfizer. Several statin cholesterol-lowering drugs (such as lovastatin, from Aspergillus terreus) are derived from molds. The immunosuppressant...
31 KB (3,341 words) - 11:49, 23 October 2024
from Tolypocladium inflatum. Lovastatin was the first FDA approved secondary metabolite to lower cholesterol levels. Lovastatin occurs naturally in low concentrations...
36 KB (3,720 words) - 16:45, 5 November 2024
these is monacolin K, or lovastatin (previously sold under the trade name Mevacor, and now available as generic lovastatin). Vytorin is drug that combines...
34 KB (4,113 words) - 16:29, 29 July 2024
Atorvastatin Rosuvastatin Lovastatin is derived from a fungus source and simvastatin and pravastatin are chemical modifications of lovastatin and as a result do...
23 KB (2,423 words) - 18:34, 11 September 2024
combined with lovastatin (Advicor), and with simvastatin (Simcor), as prescription drug combinations. The combination niacin/lovastatin was approved by...
92 KB (8,792 words) - 14:49, 24 September 2024
ergot alkaloids one of which is lysergic acid and Simvastatin is based on Lovastatin. Diverted total synthesis is a topic in academic research. Design and...
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activity of cerivastatin was compared to that of other statins, specifically lovastatin, simvastatin and pravastatin. This comparison was made by determining...
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chlorpromazine, reserpine, chlordiazepoxide, diazepam, and alprazolam Statins: lovastatin, pravastatin, and simvastatin Pharmaceuticals may also be described as...
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for linustatin because it is a diglucoside - in fact, the production of lovastatin inhibits linamarase cleavage of linamarin. This allows intra-plant, post-synthesis...
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medical uses. It produces a number of statins. The naturally occurring lovastatins and analogs are called monacolins K, L, J, and also occur in their hydroxyl...
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group of compounds found in yeast species: Monacolin J Monacolin K or lovastatin Monacolin M [wikidata] This set index article includes a list of related...
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liver impairment. Concomitant use with cholesterol medications such as lovastatin or simvastatin. Hypersensitivity to clarithromycin or any component of...
29 KB (2,711 words) - 14:43, 22 October 2024
Linolenic acid: α-Linolenic acid and γ-linolenic acid LOE-908 Loratadine Lovastatin Meclizine Metacycline Methylprednisolone Metyrapone Mevastatin Mifepristone...
174 KB (16,182 words) - 18:46, 5 November 2024
Linolenic acid: α-Linolenic acid and γ-linolenic acid LOE-908 Loratadine Lovastatin Meclizine Metacycline Methylprednisolone Metyrapone Mevastatin Mifepristone...
24 KB (2,105 words) - 06:45, 2 October 2024
— drugs that are broken down by CYP3A — such as simvastatin (Zocor), lovastatin (Mevacor), or atorvastatin (Lipitor) — are taken concomitantly with erythromycin...
42 KB (3,900 words) - 21:05, 19 October 2024
oyster mushroom, has been found to contain the cholesterol-lowering drug lovastatin. In one study, among 11 other commonly cultivated or foraged mushroom...
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used in medicines, such as cholecalciferol (vitamin D3), isotretinoin, lovastatin, and simvastatin, among others. The U.S. National Institutes of Health...
8 KB (619 words) - 03:36, 16 January 2024