Myostatin (also known as growth differentiation factor 8, abbreviated GDF8) is a protein that in humans is encoded by the MSTN gene. Myostatin is a myokine...
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Myostatin inhibitors are a class of drugs that work by blocking the effects of myostatin, which inhibits muscle growth. In animal models and limited human...
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Myostatin-related muscle hypertrophy is a rare genetic condition characterized by reduced body fat and increased skeletal muscle size. Affected individuals...
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natural mutation in the myostatin gene which codes for the protein, myostatin ("myo" meaning muscle and "statin" meaning stop). Myostatin is a protein that...
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Sarcopenic obesity (section Myostatin Inhibitors)
injury/inflammation in response to stress) are increased in sarcopenic obesity. Myostatin is also increased. In the fat, lipotoxicity and chronic inflammation are...
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known mutations that limits and reduces the activity of the myostatin protein. Normally, myostatin limits the number of muscle fibers present at birth, and...
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identified a natural variant of the myostatin gene found in Limousins which has a significant influence on them. The myostatin gene is found in all mammals and...
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Piedmontese cattle carry a unique gene mutation identified as an inactive myostatin allele that causes hypertrophic muscle growth, or double muscling. Purebred...
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PMID 23995658. Lee SJ, Gharbi A, Shin JE, Jung ID, Park YM (March 2021). "Myostatin inhibitor YK11 as a preventative health supplement for bacterial sepsis"...
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amount of myostatin portray deficiency in muscle development and increase of fat; on the other hand, smaller than normal amounts of myostatin greatly increase...
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Stamulumab (category Myostatin inhibitors)
Stamulumab (MYO-029) is an experimental myostatin inhibiting drug developed by Wyeth Pharmaceuticals for the treatment of muscular dystrophy (MD). Stamulumab...
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Follistatin (category Myostatin inhibitors)
its role in regulation of muscle growth in mice, as an antagonist to myostatin (also known as GDF-8, a TGF superfamily member) which inhibits excessive...
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naturally occurring gene identified as the myostatin allele mutation, or inactive myostatin gene. Myostatin prohibits muscle growth whereas an inactive...
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Gene doping (section Myostatin)
small interfering RNA. Myostatin is a protein responsible for inhibiting muscle differentiation and growth. Removing the myostatin gene or otherwise limiting...
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second leading cause of mortality in Whippets. A 2007 study identified a myostatin mutation particular to Whippets that is significantly associated with...
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; McPherron, Alexandra C. (October 2011). "Expression and Function of Myostatin in Obesity, Diabetes, and Exercise Adaptation". Medicine and Science in...
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receptors regulate muscle growth. Myostatin, a TGF-beta superfamily member, is a negative regulator of muscle growth. Myostatin binds to ACVR2B and to a lesser...
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Apitegromab (category Myostatin inhibitors)
precursor to myostatin, which limits the size of skeletal muscle tissue, as well as inactive myostatin. It does not bind to active myostatin, activin A...
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(Drm) LTBP1 Noggin TGIF Thrombospondin 1 (THBS1) Tomoregulin 1 Antibodies: Stamulumab (against myostatin) TRC105 (against endoglin) Others: Endoglin...
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monoclonal antibody that blocks the activation of the skeletal muscle protein myostatin, thereby promoting muscle tissue growth. As of 2021, the molecule showed...
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binds to myostatin, it lowers the amount of myostatin that can bind to the native receptor in the membrane (ActRIIB), preventing myostatin from delivering...
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the use of superhuman strength in fiction. Berserker Furor Teutonicus Myostatin Physical strength Hysterical strength Kumar, Rajesh (2010-09-01). "Competing...
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to myostatin, a negative regulator of muscle growth, both structurally and phylogenetically. Though GDF11 is 90% structurally similar to myostatin, GDF11's...
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total carcass fat—especially seam fat. A mutation in the 3' UTR of the myostatin gene in Texel sheep creates target sites for the microRNAs miR-1 and miR-206...
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(Drm) LTBP1 Noggin TGIF Thrombospondin 1 (THBS1) Tomoregulin 1 Antibodies: Stamulumab (against myostatin) TRC105 (against endoglin) Others: Endoglin...
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may refer to: Kocher–Debré–Semelaigne syndrome Adrenogenital syndrome Myostatin mutation resulting in hypertrophy and increased strength This disambiguation...
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and Mighty Mouse Mighty mice, a genetic strain of house mouse with the myostatin gene knocked out Mighty Mouse, the first mouse with a scroll wheel jointly...
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its side effects can be counteracted by the administration of hormones. Myostatin has been used to produce muscle hypertrophy. Sedatives may be administered...
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Eddie Hall (category People with Myostatin-related muscle hypertrophy)
Edward Stephen Hall (born 15 January 1988) is a British media personality and retired strongman. He is best known for his world-record setting 500 kg (1...
33 KB (2,843 words) - 14:36, 16 August 2024