(NOD1) is a protein receptor that in humans is encoded by the NOD1 gene. It recognizes bacterial molecules and stimulates an immune reaction . NOD1 protein...
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transactivating domain): CIITA NLRB (B for BIRs): NAIP NLRC (C for CARD): NOD1, NOD2, NLRC3, NLRC4, NLRC5 NLRP (P for PYD): NLRP1, NLRP2, NLRP3, NLRP4,...
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receptors of peptidoglycan are the NOD-like receptors (NLRs), mainly NOD1 and NOD2. The NOD1 receptor is activated after iE-DAP (γ-d-glutamyl-meso-diaminopimelic...
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protein family Nucleotide-binding oligomerization domain-containing protein 1 (NOD1), a receptor protein that recognizes foreign molecules Nucleotide-binding...
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transactivator (CIITA), IPAF, BIRC1 etc. The ligands are currently known for NOD1 and NOD2. NOD1 recognizes a molecule called meso-DAP, which is a peptidoglycan constituent...
43 KB (5,173 words) - 21:02, 10 August 2024
recognized by the cytoplasmic pattern recognition receptor (immune sensor) Nod1, which then stimulates expression of cytokines that promote inflammation...
148 KB (16,645 words) - 22:55, 3 December 2024
and form inflammasomes. Also, non-inflammasome-forming PRRs such as TLRs, NOD1 and NOD2 also play important roles in pyroptosis. These receptors upregulate...
35 KB (3,956 words) - 17:13, 28 November 2024
inducing pyroptosis in human nasal epithelial cells, which is mediated by the NOD1/2/TLR4/NLRP3 pathway. Furthermore, it has been discovered that children with...
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in apoptosis and NF-κB activation pathways. This gene is a member of the NOD1/Apaf-1 family (also known as NOD-like receptor family) and encodes a protein...
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19.12955. PMID 10224040. Inohara N, Koseki T, del Peso L, et al. (1999). "Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB". J. Biol...
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with Nod factors begins. In 2011, 2 million hectares of crops were fed with nod1 factors. Jean Dénarié's work has since focused on the myc factor and its...
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immunologist who is known for leading one of the first groups that identified NOD1 and NOD2, two important intracellular pattern recognition receptors. He is...
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have shown that TCT encourages cytokine secretion, probably through the NOD1 receptor. As a pleiotropic toxin, TCT also acts as a pyrogen and as a stimulant...
17 KB (1,695 words) - 18:16, 13 November 2023
Q8WTT2 10650 NOC4L HGNC:28461 Q9BVI4 10651 NOCT HGNC:14254 Q9UK39 10652 NOD1 HGNC:16390 Q9Y239 10653 NOD2 HGNC:5331 Q9HC29 10654 NODAL HGNC:7865 Q96S42...
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IG., and Eberl, G. lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis. 2008. Nature. 456(7221):507-510.] [Geuking...
19 KB (2,578 words) - 16:36, 5 October 2022
cells in animal models. Bacteria invasion leads to ATG16L1 recruiting by NOD1 and NOD2. This results in autophagy in RIP2/NF-κB independent manner. It...
16 KB (1,731 words) - 06:41, 27 September 2024
required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2". Immunity. 30 (6): 789–801. doi:10.1016/j.immuni.2009.04.011. PMID 19464198...
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recruitment domain-containing protein 12 (CARD12) [28][permanent dead link] NOD1: nucleotide-binding oligomerization domain containing 1 [29][permanent dead...
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(September 2000). "An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways". The Journal of Biological Chemistry. 275...
44 KB (4,951 words) - 02:32, 23 October 2024
independently of the inflammasome scaffold ASC. Human Ced4 homologs include APAF1, NOD1 (CARD4), and NOD2 (CARD15). These proteins have at least 1 N-terminal CARD...
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J, Miranda Y, Leonard N, Ulevitch R (April 2007). "SGT1 is essential for Nod1 activation". Proceedings of the National Academy of Sciences of the United...
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(September 2000). "An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways". The Journal of Biological Chemistry. 275...
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diaminopimelic acid during cell division. The peptidoglycans bind to the NOD1 receptor on intestinal epithelial cells. As a result, the intestinal epithelial...
39 KB (4,527 words) - 18:04, 13 December 2024
NLRP6, NLRP7, NLRP8, NLRP9, NLRP10, NLRP11, NLRP12, NLRP13, NLRP14, NLRX1 NOD1, NOD2 NWD1 TEP1 Koonin EV, Aravind L (May 2000). "The NACHT family - a new...
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NJ, Lee SH (2006). "Mutational analysis of P-loop domains of proapoptotic Nod1 and ARTS genes in colon carcinomas". Acta Oncologica. 45 (1): 101–2. doi:10...
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Commensal Helicobacter sp. of the Rodent Intestinal Flora Activates TLR2 and NOD1 Responses in Epithelial Cells". PLOS ONE. 4 (4): e5396. Bibcode:2009PLoSO...
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original on 22 July 2011. Retrieved 26 May 2011. "Microsoft Word – AWDNTFY_NOD1.doc" (PDF). Archived from the original (PDF) on 10 January 2009. Retrieved...
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domain-containing protein 1 (NOD1) as a negative regulator and may promote tumor growth by its inhibitory role on NOD1. PSMA7 has been shown to interact...
26 KB (3,229 words) - 22:04, 18 August 2023
Distefano, P. S.; Bertin, J; Sansonetti, P. J.; Philpott, D. J. (2003). "Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan"...
11 KB (1,032 words) - 09:12, 13 September 2024
for BIR, or Inhibitor of apoptosis domain) NAIP NLRC (C for CARD domain) NOD1 NOD2 NLRC3 NLRC4 (IPAF) NLRC5 NLRP (P for Pyrin domain) NLRP1 NLRP2 NLRP3...
38 KB (2,656 words) - 20:26, 6 November 2024