Ornithine is a non-proteinogenic α-amino acid that plays a role in the urea cycle. Ornithine is abnormally accumulated in the body in ornithine transcarbamylase...

Ornithine transcarbamylase deficiency also known as OTC deficiency is the most common urea cycle disorder in humans. Ornithine transcarbamylase, the defective...

The urea cycle (also known as the ornithine cycle) is a cycle of biochemical reactions that produces urea (NH2)2CO from ammonia (NH3). Animals that use...

The enzyme ornithine decarboxylase (EC 4.1.1.17, ODC) catalyzes the decarboxylation of ornithine (a product of the urea cycle) to form putrescine. This...

Ornithine transcarbamylase (OTC) (also called ornithine carbamoyltransferase) is an enzyme (EC 2.1.3.3) that catalyzes the reaction between carbamoyl...

Ornithine translocase is responsible for transporting ornithine from the cytosol into the mitochondria in the urea cycle. It is highly expressed in the...

an ornithine racemase (EC 5.1.1.12) is an enzyme that catalyzes the chemical reaction: L-ornithine ⇌ {\displaystyle \rightleftharpoons } D-ornithine Hence...

The enzyme ornithine cyclodeaminase (EC 4.3.1.12) catalyzes the chemical reaction L-ornithine ⇌ {\displaystyle \rightleftharpoons } L-proline + NH4+ This...

structure of arginine. Schulze and Winterstein synthesized arginine from ornithine and cyanamide in 1899, but some doubts about arginine's structure lingered...

Ornithine translocase deficiency, also called hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome, is a rare autosomal recessive urea cycle...

Ornithine aminotransferase deficiency (also known as gyrate atrophy of the choroid and retina) is an inborn error of ornithine metabolism, caused by decreased...

enzymology, an ornithine N-benzoyltransferase (EC 2.3.1.127) is an enzyme that catalyzes the chemical reaction 2 benzoyl-CoA + L-ornithine ⇌ {\displaystyle...

L-ornithine N5 monooxygenase (EC 1.14.13.195 or EC 1.14.13.196) is an enzyme which catalyzes one of the following chemical reactions: L-ornithine + NADPH...

Ornithine oxoglutarate (OGO) or ornithine α-ketoglutarate (OKG) is a drug used in liver therapy. It is the salt formed from ornithine and alpha-ketoglutaric...

N5-(carboxyethyl)ornithine synthase (EC 1.5.1.24) is an enzyme that catalyzes the chemical reaction N5-(L-1-carboxyethyl)-L-ornithine + NADP+ + H2O ⇌ {\displaystyle...

damage, in addition to gastrointestinal side effects. The combination of L-ornithine and L-aspartate (LOLA) lowers the level of ammonia in a person's blood...

molecular biology, Ornithine decarboxylase antizyme (ODC-AZ) is an ornithine decarboxylase inhibitor. It binds to, and destabilises, ornithine decarboxylase...

In enzymology, an ornithine(lysine) transaminase (EC 2.6.1.68) is an enzyme that catalyzes the chemical reaction L-ornithine + 2-oxoglutarate ⇌ {\displaystyle...

Ornithine aminotransferase (OAT) is an enzyme which is encoded in human by the OAT gene located on chromosome 10. The OAT involved in the ultimate formation...

N2-acetyl-L-ornithine + H2O ⇌ {\displaystyle \rightleftharpoons } acetate + L-ornithine Thus, the two substrates of this enzyme are N2-acetyl-L-ornithine and...

transcarbamylase, N-succinyl-L-ornithine transcarbamylase, SOTCase) is an enzyme with systematic name carbamoyl phosphate:N2-succinyl-L-ornithine carbamoyltransferase...

is taken intravenously (injection into a vein) or topically. It is an ornithine decarboxylase inhibitor. Common side effects when applied as a cream include...

In enzymology, a D-ornithine 4,5-aminomutase (EC 5.4.3.5) is an enzyme that catalyzes the chemical reaction D-ornithine ⇌ {\displaystyle \rightleftharpoons...

catalyzes the reaction N 5-acyl-L-ornithine ester + H2O ⇌ {\displaystyle \rightleftharpoons } N 5-acyl-L-ornithine + an alcohol This enzyme belongs to...

formula C7H11NO5) is biosynthesized from glutamate and acetylornithine by ornithine acetyltransferase, and from glutamic acid and acetyl-CoA by the enzyme...

then enters the urea cycle in which it reacts with ornithine (a process catalyzed by the enzyme ornithine transcarbamylase) to form citrulline. Carbamoyl...

eukaryotic cells. The precursor for synthesis of spermine is the amino acid ornithine. It is an essential growth factor in some bacteria as well. It is found...

6.1.11) is an enzyme that catalyzes the chemical reaction N2-acetyl-L-ornithine + 2-oxoglutarate ⇌ {\displaystyle \rightleftharpoons } N-acetyl-L-glutamate...

activity of any of the enzymes in the urea cycle. The most common example is ornithine transcarbamylase deficiency, which is inherited in an X-linked fashion...

1.81) is an enzyme that catalyzes the chemical reaction N2-succinyl-L-ornithine + 2-oxoglutarate ⇌ {\displaystyle \rightleftharpoons } N-succinyl-L-glutamate...