Ornithine is a non-proteinogenic α-amino acid that plays a role in the urea cycle. Ornithine is abnormally accumulated in the body in ornithine transcarbamylase...
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Ornithine transcarbamylase (OTC) (also called ornithine carbamoyltransferase) is an enzyme (EC 2.1.3.3) that catalyzes the reaction between carbamoyl...
21 KB (2,570 words) - 20:46, 22 July 2024
The enzyme ornithine decarboxylase (EC 4.1.1.17, ODC) catalyzes the decarboxylation of ornithine (a product of the urea cycle) to form putrescine. This...
19 KB (2,082 words) - 12:53, 9 January 2024
Ornithine transcarbamylase deficiency also known as OTC deficiency is the most common urea cycle disorder in humans. Ornithine transcarbamylase, the defective...
16 KB (1,696 words) - 18:55, 25 October 2023
Urea cycle (redirect from Ornithine cycle)
The urea cycle (also known as the ornithine cycle) is a cycle of biochemical reactions that produces urea (NH2)2CO from ammonia (NH3). Animals that use...
21 KB (2,219 words) - 13:28, 25 July 2024
Ornithine translocase is responsible for transporting ornithine from the cytosol into the mitochondria in the urea cycle. It is highly expressed in the...
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an ornithine racemase (EC 5.1.1.12) is an enzyme that catalyzes the chemical reaction: L-ornithine ⇌ {\displaystyle \rightleftharpoons } D-ornithine Hence...
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Ornithine oxoglutarate (OGO) or ornithine α-ketoglutarate (OKG) is a drug used in liver therapy. It is the salt formed from ornithine and alpha-ketoglutaric...
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structure of arginine. Schulze and Winterstein synthesized arginine from ornithine and cyanamide in 1899, but some doubts about arginine's structure lingered...
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The enzyme ornithine cyclodeaminase (EC 4.3.1.12) catalyzes the chemical reaction L-ornithine ⇌ {\displaystyle \rightleftharpoons } L-proline + NH4+ This...
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N5-(carboxyethyl)ornithine synthase (EC 1.5.1.24) is an enzyme that catalyzes the chemical reaction N5-(L-1-carboxyethyl)-L-ornithine + NADP+ + H2O ⇌ {\displaystyle...
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Ornithine translocase deficiency, also called hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome, is a rare autosomal recessive urea cycle...
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enzymology, an ornithine N-benzoyltransferase (EC 2.3.1.127) is an enzyme that catalyzes the chemical reaction 2 benzoyl-CoA + L-ornithine ⇌ {\displaystyle...
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Hepatic encephalopathy (redirect from L-Ornithine L-aspartate)
damage, in addition to gastrointestinal side effects. The combination of L-ornithine and L-aspartate (LOLA) lowers the level of ammonia in a person's blood...
37 KB (3,906 words) - 21:38, 30 May 2024
In enzymology, an ornithine(lysine) transaminase (EC 2.6.1.68) is an enzyme that catalyzes the chemical reaction L-ornithine + 2-oxoglutarate ⇌ {\displaystyle...
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Ornithine aminotransferase (OAT) is an enzyme which is encoded in human by the OAT gene located on chromosome 10. The OAT involved in the ultimate formation...
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is taken intravenously (injection into a vein) or topically. It is an ornithine decarboxylase inhibitor. Common side effects when applied as a cream include...
38 KB (3,966 words) - 00:02, 22 September 2024
transcarbamylase, N-succinyl-L-ornithine transcarbamylase, SOTCase) is an enzyme with systematic name carbamoyl phosphate:N2-succinyl-L-ornithine carbamoyltransferase...
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Fusarinine-C ornithinesterase (redirect from N5-acyl-L-ornithine-ester hydrolase)
catalyzes the reaction N 5-acyl-L-ornithine ester + H2O ⇌ {\displaystyle \rightleftharpoons } N 5-acyl-L-ornithine + an alcohol This enzyme belongs to...
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L-ornithine N5 monooxygenase (EC 1.14.13.195 or EC 1.14.13.196) is an enzyme which catalyzes one of the following chemical reactions: L-ornithine + NADPH...
13 KB (1,005 words) - 16:01, 30 March 2024
activity of any of the enzymes in the urea cycle. The most common example is ornithine transcarbamylase deficiency, which is inherited in an X-linked fashion...
16 KB (1,549 words) - 19:30, 6 September 2024
then enters the urea cycle in which it reacts with ornithine (a process catalyzed by the enzyme ornithine transcarbamylase) to form citrulline. Carbamoyl...
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Ornithine aminotransferase deficiency (also known as gyrate atrophy of the choroid and retina) is an inborn error of ornithine metabolism, caused by decreased...
6 KB (610 words) - 15:06, 27 October 2023
In enzymology, a D-ornithine 4,5-aminomutase (EC 5.4.3.5) is an enzyme that catalyzes the chemical reaction D-ornithine ⇌ {\displaystyle \rightleftharpoons...
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Acetylornithine deacetylase (redirect from N2-acetyl-L-ornithine amidohydrolase)
N2-acetyl-L-ornithine + H2O ⇌ {\displaystyle \rightleftharpoons } acetate + L-ornithine Thus, the two substrates of this enzyme are N2-acetyl-L-ornithine and...
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molecular biology, Ornithine decarboxylase antizyme (ODC-AZ) is an ornithine decarboxylase inhibitor. It binds to, and destabilises, ornithine decarboxylase...
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formula C7H11NO5) is biosynthesized from glutamate and acetylornithine by ornithine acetyltransferase, and from glutamic acid and acetyl-CoA by the enzyme...
15 KB (1,318 words) - 18:44, 17 August 2022
eukaryotic cells. The precursor for synthesis of spermine is the amino acid ornithine. It is an essential growth factor in some bacteria as well. It is found...
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second pathway, arginine is converted into ornithine and then ornithine is converted into putrescine by ornithine decarboxylase (ODC). Putrescine, via metabolic...
23 KB (2,185 words) - 19:05, 30 September 2024
Acetylornithine transaminase (redirect from N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase)
6.1.11) is an enzyme that catalyzes the chemical reaction N2-acetyl-L-ornithine + 2-oxoglutarate ⇌ {\displaystyle \rightleftharpoons } N-acetyl-L-glutamate...
3 KB (292 words) - 12:55, 26 August 2023