Polycystin 1 (redirect from PKD1 (gene))
Polycystin 1 (PC1) is a protein that in humans is encoded by the PKD1 gene. Mutations of PKD1 are associated with most cases of autosomal dominant polycystic...
7 KB (839 words) - 22:04, 22 December 2023
kidney problems found that 47% of tested American Shorthair cats had the PKD1 mutation, which is responsible for feline polycystic kidney disease (PKD)...
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years of age. ADPKD is genetically heterogeneous with two genes identified: PKD1 (chromosome region 16p13.3; around 85% cases) and PKD2 (4q21; around 15%...
57 KB (6,324 words) - 00:04, 30 April 2024
Genetic mutations in any of the three genes PKD1, PKD2, and PKD3 have similar phenotypical presentations. Gene PKD1 is located on chromosome 16 and codes for...
27 KB (2,796 words) - 22:39, 25 September 2024
have kidney problems found that 54% of tested Scottish Fold cats had the PKD1 mutation, which is responsible for PKD. A study in Japan found two genes...
32 KB (3,420 words) - 21:37, 5 September 2024
on structural similarity. The first group, polycystic kidney disease 1 (PKD1)-like, contains polycystin-1 (Previously known as TRPP1), PKDREJ, PKD1L1...
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disorder Pi Kappa Delta, a forensics honor society Polycystic kidney disease PKD1 and PKD2, human genes Proliferative kidney disease, caused by the parasite...
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study, all six Maine Coon cats with renal cysts tested negative for the PKD1 mutation, proving the disease in these cats to be unrelated to the PKD observed...
36 KB (3,874 words) - 04:43, 21 September 2024
suspected to have kidney problems found that 46% of tested Persian cats had the PKD1 mutation, which is responsible for feline polycystic kidney disease (PKD)...
78 KB (8,228 words) - 18:18, 23 September 2024
Polycystic kidney disease is a genetic disease caused by mutations in the PKD1, PKD2, and PKHD1 genes. This disease affects about half a million people...
24 KB (2,616 words) - 02:49, 13 August 2024
structures available for members of the PCC family. Some of these include: PKD1: PDB: 1B4R Polycystic kidney disease 2-like 1 protein: PDB: 3TE3, 4GIF...
11 KB (1,385 words) - 04:58, 3 September 2023
chromosome 16 p13.3, and was discovered in 1993. TSC2 is contiguous with PKD1, the gene involved in one form of polycystic kidney disease (PKD). Gross...
50 KB (5,493 words) - 16:48, 12 July 2024
disease. Polycystin 2 has been shown to interact with the proteins TRPC1, PKD1 and TNNI3. HAX1 TRPP GRCh38: Ensembl release 89: ENSG00000118762 – Ensembl...
11 KB (1,206 words) - 19:21, 1 August 2023
first identified in the polycystic kidney disease protein, polycystin-1 (PKD1 gene), and contains an Ig-like fold consisting of a beta-sandwich of seven...
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MARK3 MARK4 MELK MKNK1 MKNK2 NUAK1 NUAK2 OBSCN PASK PHKG1 PHKG2 PIM1 PIM2 PKD1 PRKD2 PRKD3 PSKH1 SNF1LK2 KIAA0999 STK40 SNF1LK SNRK SPEG TSSK2 Kalirin TRIB1...
45 KB (4,680 words) - 16:38, 13 September 2024
heterozygous carriers, and detect novel/rare variations. Mutations in the PKD1 and PKD2 genes which encode for polycystin-1 and polycistin-2 respectively...
35 KB (2,499 words) - 18:40, 12 July 2024
ALOX12B; ALOX12P2; ALOX15; ALOX15B; ALOX5; ALOXE3; LIPC; LIPG; LOXHD1; LPL; PKD1; PKD1L1; PKD1L2; PKD1L3; PKDREJ; PNLIP; PNLIPRP1; PNLIPRP2; PNLIPRP3; RAB6IP1;...
3 KB (295 words) - 21:27, 18 September 2021
(examples include TRPP2, TRPP3, and TRPP5) encode canonical TRP channels. PKD1-like genes encode much larger proteins with 11 transmembrane segments, which...
49 KB (5,517 words) - 15:04, 1 October 2024
activation (require phosphatidyl serine) PKC-ι (PRKCI) PKC-ζ (PRKCZ) related PKD PKD1 (PRKD1) PKD2 (PRKD2) PKD3 (PRKD3) related PKN PK-N1 (PKN1) PK-N2 (PKN2) PK-N3...
27 KB (2,716 words) - 12:30, 12 September 2024
MARK3 MARK4 MELK MKNK1 MKNK2 NUAK1 NUAK2 OBSCN PASK PHKG1 PHKG2 PIM1 PIM2 PKD1 PRKD2 PRKD3 PSKH1 SNF1LK2 KIAA0999 STK40 SNF1LK SNRK SPEG TSSK2 Kalirin TRIB1...
27 KB (2,665 words) - 17:03, 6 April 2024
dominant polycystic kidney disease (ADPKD) linked to mutations in the genes PKD1 and PKD2. While ADPKD is considered to be an adult-onset polycystic kidney...
23 KB (2,367 words) - 15:08, 10 August 2024
MARK3 MARK4 MELK MKNK1 MKNK2 NUAK1 NUAK2 OBSCN PASK PHKG1 PHKG2 PIM1 PIM2 PKD1 PRKD2 PRKD3 PSKH1 SNF1LK2 KIAA0999 STK40 SNF1LK SNRK SPEG TSSK2 Kalirin TRIB1...
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induced pluripotent stem cells from polycystic kidney disease patients with PKD1 mutations". Journal of the American Society of Nephrology. 24 (10): 1571–86...
92 KB (10,518 words) - 09:00, 6 September 2024
MARK3 MARK4 MELK MKNK1 MKNK2 NUAK1 NUAK2 OBSCN PASK PHKG1 PHKG2 PIM1 PIM2 PKD1 PRKD2 PRKD3 PSKH1 SNF1LK2 KIAA0999 STK40 SNF1LK SNRK SPEG TSSK2 Kalirin TRIB1...
119 KB (12,658 words) - 19:25, 19 September 2024
receptors, including adhesion-GPCRs and polycystic kidney disease proteins PKD1 and PKD2. The domain is involved in the self-cleavage of these transmembrane...
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MARK3 MARK4 MELK MKNK1 MKNK2 NUAK1 NUAK2 OBSCN PASK PHKG1 PHKG2 PIM1 PIM2 PKD1 PRKD2 PRKD3 PSKH1 SNF1LK2 KIAA0999 STK40 SNF1LK SNRK SPEG TSSK2 Kalirin TRIB1...
46 KB (5,492 words) - 14:52, 20 August 2024
Neurofibromatosis 17q/22q/? Phenylketonuria 12q P Polycystic kidney disease 16 (PKD1) or 4 (PKD2) P Prader–Willi syndrome 15q DCP Scheuermann's disease 1q21-q22...
42 KB (983 words) - 18:14, 6 October 2024
MARK3 MARK4 MELK MKNK1 MKNK2 NUAK1 NUAK2 OBSCN PASK PHKG1 PHKG2 PIM1 PIM2 PKD1 PRKD2 PRKD3 PSKH1 SNF1LK2 KIAA0999 STK40 SNF1LK SNRK SPEG TSSK2 Kalirin TRIB1...
57 KB (6,280 words) - 19:28, 19 September 2024
MARK3 MARK4 MELK MKNK1 MKNK2 NUAK1 NUAK2 OBSCN PASK PHKG1 PHKG2 PIM1 PIM2 PKD1 PRKD2 PRKD3 PSKH1 SNF1LK2 KIAA0999 STK40 SNF1LK SNRK SPEG TSSK2 Kalirin TRIB1...
8 KB (886 words) - 12:46, 31 January 2024
MARK3 MARK4 MELK MKNK1 MKNK2 NUAK1 NUAK2 OBSCN PASK PHKG1 PHKG2 PIM1 PIM2 PKD1 PRKD2 PRKD3 PSKH1 SNF1LK2 KIAA0999 STK40 SNF1LK SNRK SPEG TSSK2 Kalirin TRIB1...
48 KB (5,285 words) - 16:26, 21 August 2024