• Thumbnail for Phenylalanine ammonia-lyase
    enzyme phenylalanine ammonia lyase (EC 4.3.1.24) catalyzes the conversion of L-phenylalanine to ammonia and trans-cinnamic acid.: L-phenylalanine = trans-cinnamate...
    20 KB (2,181 words) - 05:06, 23 September 2024
  • Thumbnail for Histidine ammonia-lyase
    Histidine ammonia-lyase (EC 4.3.1.3, histidase, histidinase) is an enzyme that in humans is encoded by the HAL gene. It converts histidine into ammonia and...
    5 KB (638 words) - 11:14, 18 May 2024
  • Phenylalanine/tyrosine ammonia-lyase (EC 4.3.1.25, PTAL, bifunctional PAL) is an enzyme with systematic name L-phenylalanine(or L-tyrosine):trans-cinnamate(or...
    3 KB (285 words) - 12:08, 29 November 2023
  • Thumbnail for Phenylalanine
    Phenylalanine is converted to cinnamic acid by the enzyme phenylalanine ammonia-lyase. Phenylalanine is biosynthesized via the shikimate pathway. The genetic...
    28 KB (2,386 words) - 21:26, 25 July 2024
  • Thumbnail for Threonine ammonia-lyase
    Threonine ammonia-lyase (EC 4.3.1.19, systematic name L-threonine ammonia-lyase (2-oxobutanoate-forming), also commonly referred to as threonine deaminase...
    15 KB (1,683 words) - 16:02, 26 August 2023
  • dihydroxyphenylalanine ammonia-lyase (EC 4.3.1.11, entry deleted) is a non-existing enzyme that catalyzes the chemical reaction 3,4-dihydroxy-L-phenylalanine ⇌ {\displaystyle...
    2 KB (153 words) - 13:51, 26 August 2023
  • Thumbnail for Tyrosine ammonia-lyase
    Ammonia + H+ L-tyrosine = trans-p-hydroxycinnamate + NH3 EC 4.3.1.24 (phenylalanine ammonia-lyase) EC 4.3.1.25 (phenylalanine/tyrosine ammonia-lyase)...
    2 KB (212 words) - 21:37, 18 August 2023
  • DOPA-reductive deaminase, DOPARDA; systematic name 3,4-dihydroxy-L-phenylalanine ammonia-lyase (3,4-dihydroxyphenylpropanoate-forming)) catalyses the following...
    1 KB (116 words) - 04:16, 28 November 2023
  • Thumbnail for Hesperidin
    pathway, in which the natural amino acid L-phenylalanine undergoes a deamination by phenylalanine ammonia lyase to afford (E)-cinnamate. The resulting monocarboxylate...
    15 KB (1,228 words) - 16:46, 20 September 2024
  • Thumbnail for Cinnamaldehyde
    biosynthesized from phenylalanine. Deamination of L-phenylalanine into cinnamic acid is catalyzed by phenylalanine ammonia lyase (PAL). PAL catalyzes...
    20 KB (1,852 words) - 14:49, 9 September 2024
  • Thumbnail for Phenylketonuria
    clinical trials to investigate PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase or 'PAL'), which is an enzyme substitution therapy in which the...
    58 KB (6,189 words) - 23:00, 18 October 2024
  • Thumbnail for Cathinone
    khat begins with L-phenylalanine and the first step is carried out by L-phenylalanine ammonia lyase (PAL), which cleaves off an ammonia group and creates...
    27 KB (2,562 words) - 10:37, 20 September 2024
  • Thumbnail for Capsaicin
    studies identified phenylalanine and valine as the precursors to capsaicin. Enzymes of the phenylpropanoid pathway, phenylalanine ammonia lyase (PAL), cinnamate...
    59 KB (5,930 words) - 07:55, 18 October 2024
  • Thumbnail for Dehydroalanine
    important electrophilic catalytic residue in histidine ammonia-lyase and phenylalanine ammonia-lyase enzymes, but the active residue was later found instead...
    8 KB (706 words) - 04:26, 3 February 2024
  • Thumbnail for Phenylpropanoid
    and scent compounds. Phenylalanine is first converted to cinnamic acid by the action of the enzyme phenylalanine ammonia-lyase (PAL). Some plants, mainly...
    6 KB (619 words) - 17:20, 7 October 2024
  • (tyrosine ammonia-lyase), EC 4.3.1.24 (phenylalanine ammonia-lyase) and EC 4.3.1.25 (phenylalanine/tyrosine ammonia-lyase) EC 4.3.1.6: β-alanyl-CoA ammonia-lyase...
    62 KB (7,931 words) - 19:04, 4 January 2024
  • Permissive action link, a security device for nuclear weapons Phenylalanine ammonia-lyase, a class of enzymes PAL Airlines, Canada PAL Airlines (Chile)...
    4 KB (467 words) - 13:25, 8 August 2024
  • first enzyme involved is phenylalanine ammonia-lyase (PAL) that converts L-phenylalanine to trans-cinnamic acid and ammonia. Gallic acid is formed from...
    12 KB (1,163 words) - 14:21, 2 October 2024
  • Thumbnail for Quercetin
    phenylalanine is converted to 4-coumaroyl-CoA in a series of steps known as the general phenylpropanoid pathway using phenylalanine ammonia-lyase,...
    26 KB (2,467 words) - 14:07, 12 September 2024
  • 2017, Codexis developed a recombinant phenylalanine ammonia-lyase (PAL) enzyme, to act as a substitute phenylalanine hydroxylase (PAH) enzyme for people...
    7 KB (472 words) - 08:14, 19 October 2024
  • Thumbnail for Rosavin
    and the loss of a water molecule. Phenylalanine ammonia lyase (PAL) then converts phenolpyruvate to phenylalanine by using L-glutamate as an amine donor...
    8 KB (638 words) - 00:24, 7 May 2023
  • of catalase isozymes activity and jasmonate, which modulates phenylalanine ammonia lyase activity. Effectors are proteins secreted by microbial pathogens...
    5 KB (662 words) - 03:39, 3 April 2023
  • Thumbnail for Cinnamic acid
    Its biosynthesis involves the action of the enzyme phenylalanine ammonia-lyase (PAL) on phenylalanine. It is obtained from oil of cinnamon, or from balsams...
    8 KB (686 words) - 10:04, 12 August 2024
  • Thumbnail for PEGylation
    DMG-PEG 2000. Pegvaliase (Biomarin) – PEGylated recombinant phenylalanine ammonia-lyase for the treatment of Phenylketonuria, approved by the FDA for...
    27 KB (2,984 words) - 15:30, 18 October 2024
  • Thumbnail for Apigenin
    L-phenylalanine, first the amino acid is non-oxidatively deaminated by phenylalanine ammonia lyase (PAL) to make cinnamate, followed by oxidation at the para position...
    12 KB (1,094 words) - 14:22, 16 October 2024
  • 20) Category:EC 4.3.1 Phenylalanine ammonia-lyase (EC 4.3.1.24) Category:EC 4.4.1 Cystathionine gamma-lyase Cystathionine beta-lyase Leukotriene C4 synthase...
    33 KB (3,650 words) - 18:48, 10 September 2024
  • Thumbnail for Flavan-3-ol
    indicated in blue, abbreviated as follows: E1, phenylalanine ammonia lyase (PAL), E2, tyrosine ammonia lyase (TAL), E3, cinnamate 4-hydroxylase, E4, 4-coumaroyl:...
    19 KB (1,905 words) - 20:10, 13 May 2024
  • Thumbnail for Cyanidin
    acid to form L-phenylalanine (figure 1). L-phenylalanine then undergoes an elimination of the primary amine with Phenylalanine ammonia-lyase (PAL) to form...
    9 KB (817 words) - 10:13, 9 April 2024
  • Thumbnail for Silibinin
    coat. Starting with the transformation of phenylalanine into cinnamic acid mediated by phenylalanine ammonia-lyase. Cinnamic acid will then go through two...
    21 KB (2,233 words) - 08:08, 21 August 2024
  • postharvest behaviors. Phospholipid Phospholipase A2 Phospholipase D Phenylalanine ammonia lyase (PAL) Acid invertase (Ac INV) SignaFresh Phosphatidylcholine...
    5 KB (662 words) - 21:46, 9 July 2024