The renal outer medullary potassium channel (ROMK) is an ATP-dependent potassium channel (Kir1.1) that transports potassium out of cells. It plays an important...
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1 SLC12A1 (NKCC2) Na-K-2Cl symporter neonatal Bartter's syndrome type 2 ROMK/KCNJ1 thick ascending limb K+ channel classic Bartter's syndrome type 3 CLCNKB...
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Hypomagnesemia also causes activation of the Renal outer medullary potassium channel (ROMK), a potassium channel that causes potassium losses in the urine via the cortical...
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upregulatory effects on ROMK channels. miR-802 thus functions to mediate the stimulatory effect of a high potassium diet on ROMK activity through suppression...
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apical epithelial sodium channels, ENaC, as well as potassium channels, ROMK. These actions increase sodium reabsorption and potassium secretion. Since...
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membrane expression of the inward rectifier ATP-dependent potassium channel ROMK. Klotho-deficient mice show increased production of vitamin D, and altered...
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Potassium channel blocker (section ROMK (Kir1.1))
H; Syn, S; Palmer, L G; Choe, H; Walters, D E (Feb 2001). "Regulation of ROMK by extracellular cations". Biophysical Journal. 80 (2): 683–697. Bibcode:2001BpJ...
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potassium excretion via the sodium-potassium exchange mechanism (i.e. apical ROMK/Na channels coupled with basolateral Na+/K ATPases). This can result in a...
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generating the electrochemical gradient necessary for potassium efflux by ROMK channel). Treatment of severe forms of PHA1 requires relatively large amounts...
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H, Syn S, Palmer LG, Choe H, Walters DE (February 2001). "Regulation of ROMK by extracellular cations". Biophysical Journal. 80 (2): 683–697. Bibcode:2001BpJ...
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increase the activity of the basolateral Na/K ATPase, ENaC sodium channels and ROMK potassium channels of the principal cell in the distal tubule and cortical...
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Pseudopeptidoglycan Pseudopodia Pterygium Q-type calcium channel R-type calcium channel ROMK RYR1 RYR3 Radial spoke Receptor (biochemistry) Reinhart Heinrich Reversal...
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Nimesulide Rottlerin (mallotoxin) Tolfenamic acid Inwardly rectifying 2T & 1P ROMK (Kir1.1) [citation needed] none GPCR regulated (Kir3.x) [citation needed]...
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epithelial Na+ channel (ENaC), renal outer medullary potassium channel (ROMK), transient receptor potential vanilloid member 4 and 5 (TRPV4/5, calcium...
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and gene expression. Therefore, the production and expression of ENaC and ROMK electrolyte channels in the distal nephrons, which give the drug its diuretic...
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companies MariCal and Pearl Development Group. His laboratory identified ROMK, a potassium excretion regulatory channel in the kidney outer medulla involved...
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Plasma: ↑renin, ↓K, ↑CO2, mild ↓Mg in some patients; Urine: ↑Ca [601678] ROMK (type 2) 11q24 AR [241200] C1C-Kb (type 3, classic) 1p36 AR [607364] 1p31...
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potential with loss of parasympathetic control, resulting in a faster heart rate ROMK is found in the kidneys where it contributes to K+ recycling. An inhibition...
9 KB (1,140 words) - 03:11, 19 August 2023
Garty H, Palmer LG, Popovtzer MM (Aug 1998). "Differential regulation of ROMK expression in kidney cortex and medulla by aldosterone and potassium". The...
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TP, Olsen O, et al. (2004). "Assembly and trafficking of a multiprotein ROMK (Kir 1.1) channel complex by PDZ interactions". J. Biol. Chem. 279 (8): 6863–73...
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up-regulated by a low K intake and suppresses renal outer medullary K channels (ROMK) by MAPK stimulation". Proceedings of the National Academy of Sciences of...
10 KB (1,426 words) - 17:55, 12 May 2022