encoded by the STAT5A gene. STAT5A orthologs have been identified in several placentals for which complete genome data are available. STAT5a shares the same...
16 KB (1,831 words) - 05:07, 1 December 2023
two highly related proteins, STAT5A and STAT5B, which are part of the seven-membered STAT family of proteins. Though STAT5A and STAT5B are encoded by separate...
11 KB (1,215 words) - 11:33, 23 September 2023
proposed mechanism suggests that growth hormones may phosphorylate with STAT5A and STAT5B, transcription factors that are a part of the Signal Transducer...
17 KB (2,179 words) - 16:33, 17 August 2024
ENSG00000138378 STAT Known motif – In vivo/Misc source [888] BDHTTCTBGKAAD STAT5A ENSG00000126561 STAT Known motif – In vivo/Misc source [889] YTTCYNRGAAHY...
374 KB (81 words) - 02:10, 23 September 2023
SOCS3; SOCS4; SOCS5; SOCS6; SOCS7 SRC; SRMS STAT1; STAT2; STAT3; STAT4; STAT5A; STAT5B; STAT6 SUPT6H; SYK TEC; TENC1; TNS; TNS1; TNS3; TNS4; TXK VAV1;...
13 KB (1,341 words) - 04:09, 6 March 2024
allergies. Dr. Nadeau and her laboratory discovered novel mechanisms of STAT5a and STAT5b transcriptional factors to help understand the human immune system...
32 KB (2,991 words) - 16:42, 16 July 2024
family members that have been identified: STAT1, STAT2, STAT3, STAT4, STAT5 (STAT5A and STAT5B), and STAT6. STAT1 homodimers are involved in type II interferon...
6 KB (514 words) - 21:03, 25 November 2022
to) proteins. There are seven STAT proteins: STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B and STAT6. STAT proteins contain many different domains, each with...
62 KB (6,845 words) - 18:30, 22 August 2024
IRS1 IL12RB2 IL5RA PIK3R1 PPP2R4 PTK2 PTPN11 PTPN6 PRMT5 SH2B1 SHC1 SOCS3 STAT5A STAT5B STAM SOCS1 TEC TNFRSF1A VAV1 YES1 Prolactin signals through JAK2...
28 KB (3,166 words) - 19:57, 8 August 2024
PTPN11, PTPN6, PTPRK, SH2D3A, SH3KBP1, SHC1, SOS1, Src, STAT1, STAT3, STAT5A, UBC, and WAS, PAR2. In fruitflies, the epidermal growth factor receptor...
60 KB (6,879 words) - 14:26, 16 July 2024
P52630 15935 STAT3 HGNC:11364 P40763 15936 STAT4 HGNC:11365 Q14765 15937 STAT5A HGNC:11366 P42229 15938 STAT5B HGNC:11367 P51692 15939 STAT6 HGNC:11368...
242 KB (17 words) - 23:17, 27 April 2024
Erythropoietin, Grb2, Janus kinase 2, LYN, PIK3R1, PTPN6, SOCS2, SOCS3, and STAT5A. GRCh38: Ensembl release 89: ENSG00000187266 – Ensembl, May 2017 GRCm38:...
28 KB (3,409 words) - 18:05, 8 June 2024
lateral sclerosis type 19. ERBB4 has been shown to interact with: DLG4 NRG1, STAT5A, and YAP1. GRCh38: Ensembl release 89: ENSG00000178568 – Ensembl, May 2017...
12 KB (1,597 words) - 14:14, 22 December 2023
belonging to the STAT protein family, composed of STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6. STAT proteins are key activators of gene transcription which...
17 KB (1,895 words) - 07:46, 3 June 2024
PMID 19664288. "Prolactin Inhibits BCL6 Expression in Breast Cancer through a Stat5a-Dependent Mechanism" Cancer Research Journal. Retrieved 2019-08-04. Peck...
24 KB (2,430 words) - 02:33, 20 July 2024
with: ELP2, GNB2L1 IL6ST, Grb2, IL2RB, IRS1, IL10RA, PTPN11, STAM2, STAT3, STAT5A, STAT5B, and TNFRSF1A. Janus kinase inhibitor GRCh38: Ensembl release 89:...
21 KB (2,423 words) - 03:55, 27 January 2024
Phosphatidylethanolamine binding protein 1, RPS6KA1, RPS6KA2, RPS6KA3, SORBS3, STAT5A, TNIP1, TOB1, TSC2, UBR5, and VAV1. Mutations in MAPK1 are implicated in...
20 KB (2,283 words) - 00:38, 15 June 2024
Carlo; Lodish, Harvey F. (2001-12-01). "Ineffective erythropoiesis in Stat5a−/−5b−/− mice due to decreased survival of early erythroblasts". Blood. 98...
5 KB (725 words) - 00:14, 17 August 2024
1996). "Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells". J. Biol. Chem. 271 (18):...
5 KB (526 words) - 12:21, 14 January 2024
GAB1, GAB2, INPP5D, MAP4K1, MAP4K5, NEDD9, PIK3R2, Paxillin RAPGEF1, RICS, STAT5A, Syk, and WAS. Crk GRCh38: Ensembl release 89: ENSG00000099942 – Ensembl...
27 KB (3,165 words) - 08:10, 5 January 2024
Ku70, Lamin B receptor, MBD1, MIS12, SMARCA4, SUV39H1, TAF4, and TRIM28. STAT5A, Heterochromatin protein 1 GRCh38: Ensembl release 89: ENSG00000094916 –...
20 KB (2,431 words) - 05:48, 3 June 2024
crest origin cells and development of the peripheral nervous system), and STAT5A (a transcription factor) but lack antibody-detectable TP63 (a transcription...
16 KB (1,955 words) - 01:29, 20 August 2023
v t e Regulome Activates MAP kinase, FLT3, STAT5A Inhibits tyrosine kinase, PSA...
7 KB (724 words) - 01:47, 28 August 2024
leukemias. NMI (gene) has been shown to interact with BRCA1, IFI35, Myc, and STAT5A, and TUBA3C. GRCh38: Ensembl release 89: ENSG00000123609 – Ensembl, May...
9 KB (1,163 words) - 19:47, 3 March 2023
LRP1, PDGFRB, PI3K → Akt PLCG2, PTK2B, Ras SLAMF1, SOCS3, SOS1, STAT3, STAT5A, and STAT5B. CagA is a protein and virulence factor inserted by Helicobacter...
37 KB (4,304 words) - 05:41, 17 June 2024
binding sites for a number of additional transcription factors, including STAT5A and NF-kappa B. In the 3'UTR of NEDD9 is a match to positions 2-8 of mature...
64 KB (8,012 words) - 11:54, 5 January 2024
Marignol L, Ree AH (2013). "Hypoxic tumor kinase signaling mediated by STAT5A in development of castration-resistant prostate cancer". PLOS ONE. 8 (5):...
41 KB (4,850 words) - 16:01, 30 March 2024
B, Xu H, Zhuang Q, Zhao C, Qu L, Shou C (October 2014). "Inhibition of STAT5a by Naa10p contributes to decreased breast cancer metastasis". Carcinogenesis...
43 KB (5,405 words) - 18:27, 8 March 2024