as TRPC6, is a protein encoded in the human by the TRPC6 gene. TRPC6 is a transient receptor potential channel of the classical TRPC subfamily. TRPC6 channels...
20 KB (2,165 words) - 17:13, 2 October 2024
and activating the transient receptor potential cation channel TRPC6. Activation of TRPC6 induces the entry of calcium (Ca2+) and sodium (Na+) into the...
19 KB (1,909 words) - 02:26, 28 March 2024
TRPC1 can coassemble, complicating the understanding of this phenomenon. TRPC6 has been implicated in late onset Alzheimer's disease. Research on the role...
10 KB (1,172 words) - 18:15, 24 September 2024
biosynthesis Hypericum perforatum [St. John's Wort (SJW)] (Jarsin, Kira, Movina) – TRPC6 activator, and various other actions Oxitriptan [5-Hydroxytryptophan (5-HTP)]...
17 KB (1,478 words) - 23:23, 28 July 2024
the TRPC family of calcium channels, with selectivity for the TRPC3 and TRPC6 subtypes. It has been used to investigate the role of TRPC channels in heart...
3 KB (225 words) - 00:31, 2 December 2023
that contribute to HPV, such as transient receptor potential canonical 6 (TRPC6) channels, and transient receptor potential vanilloid 4 (TRPV4) channels...
9 KB (959 words) - 19:42, 27 August 2024
has a very similar pharmacological profile to hyperforin and acts as a TRPC6 ion channel activator, thereby inhibiting the reuptake of various neurotransmitters...
2 KB (107 words) - 16:29, 6 September 2022
the TRPC family of calcium channels, with selectivity for the TRPC3 and TRPC6 subtypes. It has been used to investigate the role of TRPC3/6 channels in...
2 KB (168 words) - 20:02, 22 January 2023
acetylcholine receptor M3 Transient receptor potential TRPC1, TRPC3, TRPC4, TRPC6 Alvin Wong, a Catholic bioethicist, argues that despite the uncertainty...
25 KB (3,066 words) - 02:55, 11 July 2024
sensor domain of voltage gated ion channels. TRPC1; TRPC3; TRPC4; TRPC5; TRPC6; TRPC7 TRPM1; TRPM2; TRPM3; TRPM4; TRPM5; TRPM6; TRPM7; TRPM8 TRPV1; TRPV2;...
19 KB (1,692 words) - 03:53, 29 November 2023
Thomas; Schultz, Günter (January 14, 1999). "Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol". Nature. 397 (6716): 259–263. Bibcode:1999Natur...
12 KB (1,027 words) - 03:41, 30 July 2024
(decreasing phosphate reabsorption in the kidney) and decreasing that of TRPC6 (decreasing phosphate absorption from the intestine). α-klotho increases...
35 KB (3,774 words) - 03:06, 29 September 2024
bind to and reduce the activity of prostaglandin F synthase and activate TRPC6. Scientists led by Claude Winder from Parke-Davis invented FFA in 1963,...
13 KB (1,088 words) - 07:57, 1 May 2024
24 is a protein that in humans is encoded by the RNF24 gene. RNF24 binds TRPC6 (603652) and other transient receptor potential cation channel (TRPC) family...
2 KB (335 words) - 10:52, 17 October 2022
proteins often leads to tumorigenesis, as reported for TRPV1, TRPV6, TRPC1, TRPC6, TRPM4, TRPM5, and TRPM8. TRPV1 and TRPV2 have been implicated in breast...
49 KB (5,517 words) - 15:04, 1 October 2024
reticulum of the cell. TRPC6 is a calcium-permeable non-selective cation channel expressed in the cardiovascular system. TRPC6 is potentially a sensor...
66 KB (7,825 words) - 22:28, 16 July 2024
G-proteins activate the phospholipase C PLCB4, which causes the TRP-channels TRPC6 and TRPC7 mediate to open so that the cell depolarizes. This is like in...
39 KB (4,525 words) - 07:01, 5 April 2024
Takimoto E, Tomaselli GF and Kass DA. Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT...
17 KB (2,176 words) - 15:25, 6 March 2024
mechanosensitive channels from the Piezo and TRP families, such as Piezo1 and TRPC6 which are generally bilayer tension-sensitive. This corresponds to the strong...
14 KB (1,193 words) - 08:34, 26 October 2023
parenchyma of smokers. Nox2 has been shown to interact directly with podocyte TRPC6 channels. GRCh38: Ensembl release 89: ENSG00000165168 – Ensembl, May 2017...
20 KB (2,434 words) - 00:26, 3 December 2023
certain other species such as mouse. TRPC2 has been shown to interact with TRPC6. TRPC GRCh38: Ensembl release 89: ENSG00000182048 – Ensembl, May 2017 "Human...
3 KB (310 words) - 23:29, 7 March 2022
Q8TEL6 17466 TRPC5 HGNC:12337 Q9UL62 17467 TRPC5OS HGNC:40593 A6NMA1 17468 TRPC6 HGNC:12338 Q9Y210 17469 TRPC7 HGNC:20754 Q9HCX4 17470 TRPM1 HGNC:7146 Q7Z4N2...
242 KB (17 words) - 18:43, 6 October 2024
TEX14; TNKS; TNKS2; TNNI3K; TP53BP2; TRP7; TRPA1; TRPC3; TRPC4; TRPC5; TRPC6; TRPC7; TRPV1; TRPV2; TRPV3; TRPV4; TRPV5; TRPV6; UACA; USH1G; ZDHHC13;...
14 KB (1,393 words) - 19:22, 1 December 2023
channel TPCN1 TPCN2 TRPA (channel) TRPC TRPC1 TRPC2 TRPC3 TRPC4AP TRPC5 TRPC6 TRPC7 TRPM TRPM1 TRPM2 TRPM3 TRPM4 TRPM5 TRPM6 TRPM7 TRPM8 TRPML TRPN TRPP...
15 KB (1,545 words) - 18:32, 17 August 2024
compound, Pyr3 TRPC3 has been shown to specifically interact with TRPC1 and TRPC6. Transient receptor potential channel TRPC GRCh38: Ensembl release 89: ENSG00000138741...
10 KB (1,218 words) - 14:58, 14 March 2023
PIK3R2, PRKCQ, PTK2B, PTK2, PTPRT UNC119, RICS, SH2D1A, SKAP1, Syk, TNK2, TRPC6, Tau protein, TrkB, TYK2, TUBA3C, WAS, and ZAP-70, The Src family of kinases...
40 KB (4,778 words) - 18:07, 30 March 2024
Swaim WD, Liu X, et al. (2005). "Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+...
8 KB (1,057 words) - 11:39, 17 January 2024
Protease 1 Serine protease essential for adaptive immune response 0.808 TRPC6 Transient Receptor Potential Cation Channel Receptor activated calcium channel...
17 KB (1,184 words) - 22:02, 2 December 2023
Patterson RL, Ambudkar IS (2005). "Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+...
12 KB (1,462 words) - 07:11, 10 March 2024
segmental, 1; 603278; ACTN4 Glomerulosclerosis, focal segmental, 2; 603965; TRPC6 Glomerulosclerosis, focal segmental, 3; 607832; CD2AP Glomerulosclerosis...
234 KB (18,877 words) - 15:43, 9 May 2024