• Thumbnail for TRPM6
    TRPM6 is a transient receptor potential ion channel associated with hypomagnesemia with secondary hypocalcemia. TRPM Ruthenium red GRCh38: Ensembl release...
    2 KB (281 words) - 20:54, 20 June 2023
  • occurs by membrane transport through the TRPM6 ion channels and is crucial for magnesium homeostasis. TRPM6 is expressed on the part of the cell membrane...
    12 KB (1,033 words) - 17:35, 28 October 2024
  • homologues have been identified, along with two novel Mg2+ transport systems TRPM6/TRPM7 and PCLN-1. Finally, in plants, a family of Mrs2p homologues has been...
    93 KB (12,023 words) - 08:10, 10 June 2024
  • motifs but, rather, contain entire functional proteins in their C-termini. TRPM6 and TRPM7, for example, contain functional α-kinase segments, which are...
    7 KB (821 words) - 22:40, 16 July 2024
  • Thumbnail for Gitelman syndrome
    Na+/K+-ATPase. Indicated also are the recently identified magnesium channel TRPM6 in the apical membrane, and a putative Na/Mg exchanger in the basolateral...
    28 KB (2,941 words) - 15:49, 11 October 2024
  • hypomagnesemia, Other genetic causes of hypomagnesemia, such as mutations in TRPM6, CNNM2, EGF, EGFR, KCNA1 or FAM111A. Many of the proteins encoded by these...
    44 KB (4,489 words) - 18:20, 17 August 2024
  • Thumbnail for Magnesium in biology
    Konrad M, Gudermann T (2004). "Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia"...
    86 KB (10,448 words) - 23:39, 22 October 2024
  • Thumbnail for Ruthenium red
    These include mammalian ion channels (CatSper1, TASK, RyR1, RyR2, RyR3, TRPM6, TRPM8, TRPV1, TRPV2, TRPV3, TRPV4, TRPV5, TRPV6, TRPA1, mCa1, mCa2, CALHM1)...
    6 KB (487 words) - 19:02, 22 September 2023
  • Thumbnail for Alexey G. Ryazanov
    kinases that include elongation factor-2 kinase (eEF2K) and channel-kinases TRPM6 and TRPM7. Ryazanov and his colleagues demonstrated that eEF2K is a regulator...
    7 KB (673 words) - 22:55, 22 February 2024
  • Thumbnail for Cation channel superfamily
    TRPC1; TRPC3; TRPC4; TRPC5; TRPC6; TRPC7 TRPM1; TRPM2; TRPM3; TRPM4; TRPM5; TRPM6; TRPM7; TRPM8 TRPV1; TRPV2; TRPV3; TRPV4; TRPV5; TRPV6 MCOLN1; MCOLN2; MCOLN3;...
    19 KB (1,692 words) - 03:53, 29 November 2023
  • and βTRPM. αTRPMs include vertebrate TRPM1, TRPM3, and the "chanzymes" TRPM6 and TRPM7, as well as the only insect TRPM channel, among others. βTRPMs...
    49 KB (5,517 words) - 15:04, 1 October 2024
  • Q9HCF6 17473 TRPM4 HGNC:17993 Q8TD43 17474 TRPM5 HGNC:14323 Q9NZQ8 17475 TRPM6 HGNC:17995 Q9BX84 17476 TRPM7 HGNC:17994 Q96QT4 17477 TRPM8 HGNC:17961 Q7Z2W7...
    242 KB (17 words) - 18:43, 6 October 2024
  • Thumbnail for Rivka Carmi
    Barbara; Beck, Gretel E.; Englehardt, Richard K. (1 June 2002). "Mutation of TRPM6 causes familial hypomagnesemia with secondary hypocalcemia". Nature Genetics...
    25 KB (2,526 words) - 05:11, 1 November 2024
  • Thumbnail for TRPM7
    S2CID 16274084. Chubanov V, Gudermann T, Schlingmann KP (2005). "Essential role for TRPM6 in epithelial magnesium transport and body magnesium homeostasis". Pflügers...
    4 KB (548 words) - 23:09, 29 October 2024
  • TRPC2 TRPC3 TRPC4AP TRPC5 TRPC6 TRPC7 TRPM TRPM1 TRPM2 TRPM3 TRPM4 TRPM5 TRPM6 TRPM7 TRPM8 TRPML TRPN TRPP TRPP3 TRPV TRPV1 TRPV2 TRPV3 TRPV4 TRPV5 TRPV6...
    15 KB (1,545 words) - 18:32, 17 August 2024
  • renal; 611718; EGF Hypomagnesemia with secondary hypocalcemia; 602014; TRPM6 Hypomagnesemia, primary; 248250; CLDN16 Hypomagnesemia, renal, with ocular...
    234 KB (18,877 words) - 06:16, 6 November 2024