000/μL, although exceptions to this observation have been documented. Thrombopoetin analogues have been tested extensively for the treatment of ITP. These...

other hand, high platelet and megakaryocyte concentrations lead to more thrombopoetin destruction and thus less availability of thrombopoietin to bone marrow...

line therapies fail and thrombocytopenia persists) include rituximab, thrombopoetin receptor agonsists (such as romiplostim), or a splenectomy. Platelet...