The voltage clamp is an experimental method used by electrophysiologists to measure the ion currents through the membranes of excitable cells, such as...
26 KB (3,681 words) - 06:30, 11 January 2024
excursions of a signal to a defined voltage by adding a variable positive or negative DC voltage to it. The clamper does not restrict the peak-to-peak...
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Electrophysiology (redirect from Planar patch clamp)
squid (Loligo pealei), and were among the first applications of the "voltage clamp" technique. Today, most microelectrodes used for intracellular recording...
39 KB (4,513 words) - 10:23, 25 August 2024
prepared giant spheroplasts. Patch clamping can be performed using the voltage clamp technique. In this case, the voltage across the cell membrane is controlled...
30 KB (3,853 words) - 01:56, 5 June 2024
different clamps used in a tube and clamp scaffold) Nipple clamp Voltage clamp A push-pull toggle clamp Operation of a latch clamp Surgical clamp A hand...
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voltage clamp, which is an electronic feedback circuit, allows the experimenter to maintain the membrane potential at a fixed point and the voltage clamp...
9 KB (1,079 words) - 05:36, 13 October 2022
will describe these formulations in more detail. Using a series of voltage clamp experiments and by varying extracellular sodium and potassium concentrations...
21 KB (3,045 words) - 04:15, 1 August 2024
Look up clamp or clamps in Wiktionary, the free dictionary. Clamp may refer to: Brick clamp, an early method of baking bricks Clamp (tool), a device or...
2 KB (326 words) - 17:56, 22 September 2022
electronic engineering, a current clamp, also known as current probe, is an electrical device with jaws which open to allow clamping around an electrical conductor...
9 KB (1,245 words) - 16:40, 30 August 2024
Schottky diode (section Voltage clamping)
to 0.46 V (see the 1N5817 and 1N5711), which makes them useful in voltage clamping applications and prevention of transistor saturation. This is due to...
21 KB (2,490 words) - 18:12, 2 September 2024
Synthetic ion channels (section Voltage response)
are usually characterized by a combination of single-molecule (e.g., voltage-clamp of planar bilayers) and ensemble techniques (flux in vesicles). The...
30 KB (3,035 words) - 23:30, 16 July 2024
patch clamp technique having ethanol as a treatment. Recordings were replicated at varying concentrations (0, 10, 25, 50, and 100 mM) at a voltage clamp of...
29 KB (3,270 words) - 15:49, 13 July 2024
Surge protector (redirect from Transient voltage suppressor)
specifications that characterize this device are: the clamping voltage, or the transient voltage at which the device starts functioning, the Joule rating...
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Ion channel (section Voltage-gated)
electrophysiology, and pharmacology, while using techniques including voltage clamp, patch clamp, immunohistochemistry, X-ray crystallography, fluoroscopy, and...
44 KB (5,175 words) - 04:08, 10 September 2024
and later the NIH. Moore became one of the earliest adopters of the voltage clamp technique, which Cole had invented and had shown to Alan Hodgkin and...
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Diode (redirect from Diode forward voltage drop)
the n-type material, such that the reverse voltage is "clamped" to a known value (called the Zener voltage), and avalanche does not occur. Both devices...
64 KB (7,303 words) - 18:03, 2 September 2024
(intracellular recording of the properties of single neurons), such as patch clamp, voltage clamp, extracellular single-unit recording and recording of local field...
16 KB (1,839 words) - 13:22, 8 August 2024
induced voltage exceeds the avalanche breakdown potential. It is a clamping device, suppressing all overvoltages above its breakdown voltage. It automatically...
7 KB (594 words) - 03:38, 8 June 2024
Tetrodotoxin (category Voltage-gated sodium channel blockers)
Narahashi and John W. Moore at Duke University, using the sucrose gap voltage clamp technique. Apart from their bacterial species of most likely ultimate...
67 KB (6,817 words) - 09:15, 13 September 2024
applied the voltage clamp technique to determine the dependence of the axonal membrane's permeabilities to sodium and potassium ions on voltage and time...
149 KB (16,431 words) - 05:24, 30 July 2024
in The Journal of Neuroscience, Cummins et al., demonstrated, using voltage clamp recordings, that these mutations enhanced the function of NaV1.7 sodium...
52 KB (6,120 words) - 04:04, 24 June 2024
Stewart Cole invented an electronic circuit which he called a voltage clamp. The voltage clamp was used to analyze the ionic conduction in nerves. The 1960s...
29 KB (3,085 words) - 05:27, 10 July 2024
experimental advantage for Hodgkin and Huxley as it allowed them to insert voltage clamp electrodes inside the lumen of the axon. While the squid axon is very...
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Multimeter (redirect from Burden voltage)
standard adapters or devices such as voltage multiplier or thermocouple probes to be plugged in. Clamp meters clamp around a conductor carrying a current...
52 KB (6,835 words) - 07:35, 4 September 2024
Retrieved 2018-06-01. Nowotny, Dr Thomas; Levi, Dr Rafael (2014). "Voltage-Clamp Technique". In Jaeger, Dieter; Jung, Ranu (eds.). Encyclopedia of Computational...
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Baker clamp by some sources, while others only call the two-diode circuit a Baker clamp. A simple alternative to the Baker clamp is a single low-voltage diode...
11 KB (1,326 words) - 04:05, 23 September 2023
revolutionary measurement approach – the Discontinuous Single-Electrode Voltage Clamp. Axon Instruments In 1983, Finkel founded Axon Instruments Inc, in Silicon...
21 KB (2,092 words) - 05:14, 17 June 2024
gap can be used as a voltage clamp as well. When used with proper electronics, the double sucrose gap can be used to voltage clamp the membrane potential...
14 KB (1,825 words) - 23:45, 12 June 2024
Repolarization (section Voltage gated K+ mechanisms)
microsecond action potentials that requires quick repolarization. Utilizing voltage-clamp data from experiments based on rodent neurons, the Kv4 channels are...
21 KB (2,413 words) - 04:36, 22 June 2024
neurons. Several techniques such as intracellular recording, patch-clamp, and voltage-clamp technique, pharmacology, confocal imaging, molecular biology, two...
12 KB (1,398 words) - 05:16, 30 July 2024