• Thumbnail for Proto-oncogene Wnt-1
    Proto-oncogene Int-1 homolog is a protein that in humans is encoded by the WNT1 (INT1) gene. The WNT gene family consists of structurally related genes that...
    9 KB (1,008 words) - 17:50, 10 April 2024
  • localisation element 3 (WLE3) WNT1-inducible-signaling pathway protein 1 (WISP1) WNT1-inducible-signaling pathway protein 2 (WISP2) WNT1-inducible-signaling pathway...
    64 KB (7,427 words) - 21:08, 3 August 2024
  • Thumbnail for Metencephalon
    processing. Two of the major genes that affect the metencephalon are Fgf8 and Wnt1, which are both expressed around the isthmus. Fgf8 is also known as Fibroblast...
    5 KB (513 words) - 05:25, 4 January 2020
  • Thumbnail for WNT1-inducible-signaling pathway protein 3
    WNT1-inducible-signaling pathway protein 3 (WISP3, also named CCN6) is a matricellular protein that in humans is encoded by the WISP3 gene. It is a member...
    5 KB (625 words) - 23:38, 3 March 2023
  • Thumbnail for WNT1-inducible-signaling pathway protein 2
    WNT1-inducible-signaling pathway protein 2, or WISP-2 (also named CCN5) is a matricellular protein that in humans is encoded by the WISP2 gene. The CCN...
    6 KB (724 words) - 04:12, 29 December 2023
  • tube. Wnt1 is mainly expressed in the entire midbrain (Otx2 expressing cells) at first. Once the midbrain/hindbrain boundary has formed, Wnt1 expression...
    6 KB (690 words) - 19:56, 3 January 2024
  • Thumbnail for Mesoderm
    the cartilage and bone formation. The neural tube activates the protein WNT1 that expresses PAX 2 so the somite creates the myotome and dermatome. Finally...
    16 KB (1,871 words) - 15:24, 3 August 2024
  • Thumbnail for Osteogenesis imperfecta
    Type XV – OI caused by homozygous or compound heterozygous mutations in the WNT1 gene on chromosome 12q13.12. It is autosomal recessive. Type XVI – OI caused...
    150 KB (15,363 words) - 14:58, 14 July 2024
  • Thumbnail for WNT1-inducible-signaling pathway protein 1
    WNT1-inducible-signaling pathway protein 1 (WISP-1), also known as CCN4, is a matricellular protein that in humans is encoded by the WISP1 gene. WISP-1...
    11 KB (1,324 words) - 23:37, 7 September 2023
  • Thumbnail for PAX2
    factor 8 (FGF8) and Wingless-Type MMTV Integration Site Family, Member 1 (Wnt1) control expression of Pax-2 during development of the Mesencephalon, or...
    14 KB (1,868 words) - 13:45, 27 January 2024
  • quantum mechanics WISP1, WISP2, and WISP3, the human genes encoding the WNT1 Inducible Signaling Pathway proteins 1, 2, and 3 Wireless Internet service...
    1 KB (218 words) - 14:53, 21 April 2024
  • ..., Sn) S1O1...SnO1 ... S1On...SnOn S1T1...SnT1 ... S1Tn...SnTn Weaknesses (W1, W2, ..., Wn) W1O1...WnO1 ... W1On...WnOn W1T1...WnT1 ... W1Tn...WnTn...
    15 KB (1,965 words) - 11:17, 23 November 2023
  • Thumbnail for FLP-FRT recombination
    recombinase in mice. The authors created a two transgenic mouse lines: a neuronal Wnt1::Flp fusion line and a line that possessed the FRT cassette flanking the...
    21 KB (2,655 words) - 10:31, 15 May 2024
  • Thumbnail for Primitive streak
    the streak-inducing ability of the marginal zone. Misexpression of Vg1 or Wnt1 alone failed to induce an ectopic streak in the chick, but together their...
    23 KB (2,803 words) - 21:33, 7 April 2024
  • Thumbnail for Myogenesis
    protein production. Meanwhile, Myf5 expression is regulated by Sonic hedgehog, Wnt1, and MyoD itself. By noting the role of MyoD in regulating Myf5, the crucial...
    24 KB (2,738 words) - 04:06, 17 June 2024
  • Thumbnail for Waardenburg syndrome type 1
    controls the neural crest development through regulation of c-RET, TGF-b2, and WNT1 which are essential controllers of migration and differentiation. PAX3 in...
    12 KB (1,465 words) - 20:49, 15 February 2024
  • involved creating the Wnt1 Zero-Mouse, a model demonstrating the dependence of oculomotoric and trochlear motoneurons on Wnt1 and Fgf8 proteins for normal...
    12 KB (1,182 words) - 09:32, 30 July 2024
  • Thumbnail for Gómez–López-Hernández syndrome
    Gómez–López-Hernández syndrome have also come from Brazil. Lack of expression from the WNT1, FGF8, FGF17, OTX2, fgf8, and fgf17 genes have all been implicated as possibly...
    14 KB (1,614 words) - 15:37, 2 November 2023
  • retroflexus and the habenula have been observed to be dependent of the presence Wnt1, as shown in a rat study. When FR are lesioned artificially, a reduction...
    9 KB (1,050 words) - 15:43, 30 July 2024
  • CCN3: Nephroblastoma overexpressed (NOV) CCN4: WNT1-inducible-signaling pathway protein 1 (WISP1) CCN5: WNT1-inducible-signaling pathway protein 2 (WISP2)...
    5 KB (570 words) - 01:53, 31 December 2020
  • University of California, San Francisco. In 1982, Nusse and Varmus discovered the Wnt1 gene. After his postdoctoral fellowship, Nusse joined the Netherlands Cancer...
    5 KB (339 words) - 15:33, 12 January 2023
  • Thumbnail for MyoD
    cis-element interactions with a distal enhancer and Wnt response element. Wnt1 from dorsal neural tube and Wnt6/Wnt7a from surface ectoderm have also been...
    27 KB (3,374 words) - 10:55, 15 July 2024
  • overexpressed) CCN4: WISP1 (WNT1 inducible signaling pathway protein-1) CCN5: WISP2 (WNT1 inducible signaling pathway protein-2) CCN6: WISP3 (WNT1 inducible signaling...
    7 KB (750 words) - 03:19, 20 July 2024
  • HGNC:14542 Q9Y3S1 18324 WNK3 HGNC:14543 Q9BYP7 18325 WNK4 HGNC:14544 Q96J92 18326 WNT1 HGNC:12774 P04628 18327 WNT2 HGNC:12780 P09544 18328 WNT2B HGNC:12781 Q93097...
    242 KB (17 words) - 23:17, 27 April 2024
  • Thumbnail for LBH (gene)
    breast cancers. Studies examining the role of Lbh in tumorigenesis in MMTV-Wnt1 transgenic mice as a model for Wnt induced breast cancer development. Lbh...
    13 KB (1,576 words) - 19:25, 10 December 2023
  • toe bones as well as other tubular bones. PPD is caused by changes in the Wnt1-inducible signalling protein 3 (WISP3) gene, also known as the CCN6 gene...
    5 KB (450 words) - 16:18, 3 December 2023
  • Thumbnail for SIX3
    whether the gene is active or inactive. Activity of the SIX3 gene represses Wnt1 gene activity which ensures development of the forebrain and establishes...
    12 KB (1,467 words) - 23:21, 28 December 2023
  • function. This complex enhances transcription of specific genes, including Wnt1 and the metastasis-associated protein KAI1, and thereby causes cancer growth...
    15 KB (1,889 words) - 13:44, 16 September 2021
  • firmly established for HBRV. The over-expression in human MCF7 cells of both WNT1 and FGF3 genes, main integration sites (INT) of MMTV in mouse, induces the...
    31 KB (3,398 words) - 09:34, 26 July 2024
  • Thumbnail for Subcommissural organ
    "Hydrocephalus and abnormal subcommissural organ in mice lacking presenilin-1 in Wnt1 cell lineages". Brain Research. 1382: 275–81. doi:10.1016/j.brainres.2011...
    29 KB (3,545 words) - 16:19, 23 May 2024