synthetase family member 3 is an enzyme that in humans is encoded by the ACSF3 gene. The ACSF3 gene is located on the 16th chromosome, with its specific location...
5 KB (599 words) - 15:20, 8 July 2024
fatty acid synthesis (mtFASII) from malonic acid by malonyl-CoA synthetase (ACSF3). MCAT is also involved in bacterial polyketide biosynthesis. The enzyme...
6 KB (574 words) - 09:54, 7 March 2024
of the mitochondrial enzyme Acyl-CoA synthetase family member 3 (ACSF3). The ACSF3 gene is located on chromosome 16 locus q24.3 and consists of 11 exons...
31 KB (3,256 words) - 19:45, 30 October 2024
Huizing, Marjan; Barshop, Bruce A (2011). "Exome sequencing identifies ACSF3 as a cause of combined malonic and methylmalonic aciduria". Nature Genetics...
42 KB (983 words) - 18:14, 6 October 2024
it is converted to malonyl-CoA by acyl-CoA synthetase family member 3 (ACSF3). Additionally, the coenzyme A derivative of malonate, malonyl-CoA, is an...
20 KB (1,985 words) - 02:27, 6 September 2024
malonyl-CoA is formed from malonic acid with the help of malonyl-CoA synthetase (ACSF3), which then becomes the final product octanoyl-ACP (C8) via further intermediate...
41 KB (4,751 words) - 20:26, 4 September 2024
malonyl-CoA for mitochondrial fatty acid synthesis (mtFASII) in tandem with ACSF3. The regulation of mammalian ACC is complex, in order to control two distinct...
27 KB (2,990 words) - 21:27, 4 July 2024
enzymes: methylmalonyl-CoA mutase (MUT) acyl-CoA synthetase family member 3 (ACSF3) methylmalonyl-CoA epimerase (MCEE) enzymes involved in adenosylcobalamin...
48 KB (4,435 words) - 15:54, 30 October 2024
D-methylmalonyl-CoA hydrolase. The enzyme acyl-CoA synthetase family member 3 (ACSF3) is in turn responsible for the conversion of methylmalonic acid and CoA...
13 KB (1,215 words) - 14:50, 12 October 2024
metabolic disease combined malonic and methylmalonic aciduria (CMAMMA) due to ACSF3 deficiency, mitochondrial fatty acid synthesis (mtFASII), which is the precursor...
48 KB (4,967 words) - 06:52, 17 October 2024
Dorward HM, Huizing M, Barshop BA (2011). "Exome sequencing identifies ACSF3 as a cause of combined malonic and methylmalonic aciduria". Nature Genetics...
65 KB (6,264 words) - 07:22, 23 October 2024
and methylmalonic aciduria (CMAMMA), acyl-CoA synthetase family member 3 (ACSF3) is reduced, which converts toxic methylmalonic acid to methylmalonyl-CoA...
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metabolic disease combined malonic and methylmalonic aciduria (CMAMMA) due to ACSF3 deficiency, mitochondrial fatty acid synthesis (mtFASII) is impaired, which...
17 KB (1,893 words) - 16:48, 27 June 2024
chromosome 16. For complete list, see the link in the infobox on the right. ACSF3: encoding enzyme Acyl-CoA synthetase family member 3 ACSM2B: encoding enzyme...
24 KB (1,670 words) - 21:40, 18 September 2024
needed] In combined malonic and methylmalonic aciduria (CMAMMA) due to ACSF3 deficiency, glycolysis is reduced by -50%, which is caused by reduced lipoylation...
82 KB (8,731 words) - 00:06, 5 November 2024
Carrillo-Carrasco N, et al. (August 2011). "Exome sequencing identifies ACSF3 as a cause of combined malonic and methylmalonic aciduria". Nat Genet. 43...
106 KB (11,283 words) - 02:43, 30 October 2024
metabolic disease combined malonic and methylmalonic aciduria (CMAMMA) due to ACSF3, a massive altered composition of complex lipids occurs as a result of impaired...
30 KB (3,361 words) - 11:32, 4 November 2024
HGNC:29567 Q96GR2 185 ACSBG2 HGNC:24174 Q5FVE4 186 ACSF2 HGNC:26101 Q96CM8 187 ACSF3 HGNC:27288 Q4G176 188 ACSL1 HGNC:3569 P33121 189 ACSL3 HGNC:3570 O95573...
277 KB (17 words) - 18:34, 6 October 2024
referred to as combined malonic and methylmalonic aciduria (CMAMMA). Although ACSF3 deficiency was not discovered until later, the term combined malonic and...
15 KB (1,717 words) - 19:44, 16 May 2024
disorder of combined malonic and methylmalonic aciduria (CMAMMA) due to ACSF3 deficiency, there is a massively increased expression of PGC-1α, which is...
32 KB (3,863 words) - 10:06, 3 November 2024
metabolic disease combined malonic and methylmalonic aciduria (CMAMMA) due to ACSF3 deficiency, there is an altered composition of complex lipids as a result...
32 KB (3,791 words) - 18:56, 19 August 2024
312863; IL2RG Combined malonic and methylmalonic aciduria (CMAMMA); 614265; ACSF3 Combined malonic and methylmalonic aciduria (CMAMMA); 248360; MLYCD Combined...
234 KB (18,877 words) - 06:16, 6 November 2024