Afatinib, sold under the brand name Gilotrif among others, is a medication which is used to treat non-small cell lung carcinoma (NSCLC). It belongs to...
15 KB (1,122 words) - 15:16, 4 August 2024
Quinazoline (section Afatinib)
approved afatinib, a drug developed by Boehringer Ingelheim, as an irreversible, competitive inhibitor of HER2 and EGFR kinases. While afatinib demonstrates...
14 KB (1,240 words) - 01:14, 27 July 2024
sofosbuvir/daclatasvir, osimertinib, crizotinib, daclatasvir, sofosbuvir, afatinib, axitinib, brigatinib, baricitinib, cabozantinib, dasatinib, neratinib...
5 KB (232 words) - 10:23, 8 March 2024
Angiokinase inhibitors (section BIBW 2992 (afatinib))
targeting receptor tyrosine kinases. Examples include nintedanib (BIBF 1120), afatinib (BIBW 2992) and motesanib (AMG 706). The term angiokinase was first documented...
12 KB (1,445 words) - 03:23, 5 December 2023
other EGFR tyrosine kinase inhibitors, such as gefitinib, erlotinib, and afatinib. In the US, EGFR exon 19 deletions, exon 21 L858R mutations or the T790M...
17 KB (1,559 words) - 21:20, 27 September 2024
(INN) afalanine (INN) afamelanotide (INN) afamitresgene autoleucel (INN) afatinib (INN, (USAN) Afaxin afegostat (USAN, INN) afelimomab (INN) afimoxifene...
5 KB (341 words) - 03:58, 5 August 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
31 KB (3,430 words) - 05:24, 28 August 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
68 KB (5,999 words) - 20:41, 31 August 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
121 KB (13,799 words) - 18:31, 13 September 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
92 KB (8,688 words) - 04:50, 27 September 2024
and infliximab are alternatives, including quality-assured biosimilars Afatinib and gefitinib are alternatives Pembrolizumab is an alternative, including...
67 KB (4,835 words) - 05:59, 17 August 2024
can be treated with EGFR inhibitors osimertinib, erlotinib, gefitinib, afatinib, or dacomitinib – with osimertinib known to be superior to erlotinib and...
90 KB (9,784 words) - 14:55, 18 September 2024
EGFR (called "EGFR inhibitors", EGFRi), including gefitinib, erlotinib, afatinib, brigatinib and icotinib for lung cancer, and cetuximab for colon cancer...
60 KB (6,879 words) - 14:26, 16 July 2024
known as tyrosine kinase inhibitors specifically, erlotinib, gefitinib, afatinib, or osimertinib. Reliable identification of mutations in lung cancer needs...
51 KB (5,333 words) - 22:13, 7 September 2024
(ipratropium bromide / salbutamol) Cosela (trilaciclib) Gilotrif / Giotrif (afatinib) Jardiance (empagliflozin) Jentadueto / TrajentaDuo (linagliptin / metformin)...
40 KB (3,324 words) - 23:21, 18 September 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
24 KB (1,710 words) - 19:18, 30 August 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
13 KB (1,177 words) - 02:19, 4 September 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
21 KB (1,808 words) - 17:43, 7 September 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
22 KB (1,787 words) - 05:10, 1 July 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
16 KB (1,784 words) - 04:08, 6 January 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
25 KB (2,086 words) - 02:24, 16 July 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
67 KB (5,974 words) - 16:40, 28 September 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
26 KB (2,420 words) - 02:40, 26 September 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
24 KB (2,872 words) - 06:27, 22 July 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
20 KB (1,566 words) - 08:58, 12 August 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
71 KB (6,702 words) - 05:32, 9 August 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
46 KB (5,344 words) - 03:26, 11 August 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
105 KB (12,338 words) - 00:34, 29 September 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
39 KB (3,854 words) - 21:20, 3 September 2024
Nepidermin Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin...
14 KB (1,689 words) - 01:31, 19 August 2024