• Thumbnail for Antithrombin
    Antithrombin (AT) is a small glycoprotein that inactivates several enzymes of the coagulation system. It is a 464-amino-acid protein produced by the liver...
    46 KB (5,418 words) - 12:45, 29 August 2024
  • Antithrombin III deficiency (abbreviated ATIII deficiency) is a deficiency of antithrombin III. This deficiency may be inherited or acquired. It is a rare...
    5 KB (474 words) - 23:41, 27 November 2023
  • Thumbnail for Coagulation
    Factor V or high levels of FVIII, also may lead to a thrombotic tendency. Antithrombin is a serine protease inhibitor (serpin) that degrades the serine proteases:...
    64 KB (6,553 words) - 17:35, 26 October 2024
  • Thumbnail for Anticoagulant
    approves Antithrombin as an anticoagulant for preventing clots before, during, or after surgery or birthing in patients with hereditary antithrombin deficiency...
    78 KB (8,755 words) - 07:51, 27 October 2024
  • Thrombin–antithrombin complex (TAT) is a protein complex of thrombin and antithrombin. It is a marker of net activation of coagulation. TAT is formed in...
    6 KB (648 words) - 03:34, 13 August 2023
  • and in vitro studies have demonstrated that protamine neutralizes the antithrombin activity of LMWHs, normalizing the aPTT and thrombin time. However, protamine...
    27 KB (3,060 words) - 14:59, 21 August 2024
  • Thumbnail for Fondaparinux
    direct factor Xa inhibitors, it mediates its effects indirectly through antithrombin III, but unlike heparin, it is selective for factor Xa. Fondaparinux...
    9 KB (711 words) - 10:19, 16 August 2023
  • transaccional (Spanish for "transactional analysis"), a psychological method Antithrombin, a small protein molecule Ataxia–telangiectasia, an immunodeficiency...
    3 KB (434 words) - 08:58, 14 July 2024
  • Thumbnail for Fresh frozen plasma
    and rechecking laboratory values. Use in antithrombin III deficiency: FFP can be used as a source of antithrombin III in patients who are deficient of this...
    17 KB (1,769 words) - 09:45, 14 January 2024
  • 774–77. PMID 9666418. MedlinePlus Encyclopedia: 003652 Antithrombin III at eMedicine Antithrombin CO000300 in Coagulation Test Handbook at Massachusetts...
    108 KB (6,105 words) - 10:44, 2 July 2024
  • Thumbnail for Thrombin
    the coagulation cascade. In human adults, the normal blood level of antithrombin activity has been measured to be around 1.1 units/mL. Newborn levels...
    25 KB (2,932 words) - 09:48, 19 October 2024
  • Thumbnail for Heparin
    glycosaminoglycan. Heparin is a blood anticoagulant that increases the activity of antithrombin. It is used in the treatment of heart attacks and unstable angina. It...
    77 KB (7,855 words) - 18:45, 29 August 2024
  • Thumbnail for ATryn
    ATryn is the brand name of the anticoagulant antithrombin manufactured by the Massachusetts-based U.S. company rEVO Biologics (formerly known as GTC Biotherapeutics)...
    6 KB (521 words) - 21:10, 27 April 2023
  • Thumbnail for Thrombophilia
    first major form of thrombophilia to be identified by medical science, antithrombin deficiency, was identified in 1965, while the most common abnormalities...
    47 KB (5,585 words) - 01:20, 24 September 2024
  • Thumbnail for Serpin
    reported in the late 1800s, but it was not until the 1950s that the serpins antithrombin and alpha 1-antitrypsin were isolated, with the subsequent recognition...
    137 KB (14,301 words) - 14:45, 2 November 2024
  • Thumbnail for Hirudin
    principal inhibitor of thrombin in normal blood circulation is antithrombin. Similar to antithrombin, the anticoagulant activity of hirudin is based on its ability...
    7 KB (818 words) - 22:18, 26 June 2024
  • Thumbnail for CSL Limited
    Rhophylac (Rh(D) immunoglobulin G) Tetanus Immunoglobulin-VF Thrombotrol-VF (antithrombin III) Vivaglobin, sub-cutaneous human immune globulin indicated for the...
    31 KB (2,916 words) - 01:35, 15 August 2024
  • lead to mutations through intrastrand and interstrand switching. The antithrombin III gene's coding region is an example of an imperfect inverted repeat...
    31 KB (3,451 words) - 20:17, 11 September 2024
  • Thumbnail for Deep vein thrombosis
    VTE rates. Genetic factors include non-O blood type, deficiencies of antithrombin, protein C, and protein S and the mutations of factor V Leiden and prothrombin...
    144 KB (14,633 words) - 21:58, 16 October 2024
  • Thumbnail for Thrombus
    cascade. Heparin works by binding to and activating the enzyme inhibitor antithrombin III, an enzyme that acts by inactivating thrombin and factor Xa. In contrast...
    21 KB (2,279 words) - 02:02, 18 September 2024
  • "Role of the antithrombin-binding pentasaccharide in heparin acceleration of antithrombin-proteinase reactions. Resolution of the antithrombin conformational...
    25 KB (3,112 words) - 19:03, 28 February 2024
  • the Antithrombin molecules in neonates and children is larger than in adults. Antithrombin: the levels of antithrombin increase with age. Antithrombin levels...
    9 KB (1,184 words) - 13:48, 7 June 2022
  • Thumbnail for Nephrotic syndrome
    particularly those caused by a decrease in blood antithrombin III levels due to leakage. Antithrombin III counteracts the action of thrombin. Thrombosis...
    57 KB (6,362 words) - 01:53, 28 October 2024
  • Thumbnail for Thrombocythemia
    By cause Clotting factors Antithrombin III deficiency Protein C deficiency Activated protein C resistance Protein S deficiency Factor V Leiden Prothrombin...
    11 KB (1,066 words) - 01:55, 17 March 2024
  • Thumbnail for Fibrinogen
    reduces the activity of thrombin. This activity, sometimes referred to as antithrombin I, limits clotting. Fibrin also mediates blood platelet and endothelial...
    37 KB (3,908 words) - 07:09, 11 May 2024
  • Thumbnail for Grifols
    Human immunoglobulin for anti-tetanus use and antithrombin produced by Grifols....
    13 KB (1,154 words) - 22:31, 30 October 2024
  • Thumbnail for Intraventricular hemorrhage
    determine the safety, dosing, and effectiveness of prophylactic heparin and antithrombin treatment for preterm neonates. In infants, germinal matrix hemorrhage...
    20 KB (2,150 words) - 22:13, 24 October 2024
  • Thumbnail for Alpha-1 antitrypsin
    An extremely rare form of Pi, termed PiPittsburgh, functions as an antithrombin (a related serpin), due to a mutation (Met358Arg). One person with this...
    33 KB (3,383 words) - 08:00, 21 August 2024
  • Thumbnail for Pulmonary heart disease
    screen- to detect chronic venous thromboembolism (proteins C and S, antithrombin III, homocysteine levels) The diagnosis of pulmonary heart disease is...
    14 KB (1,323 words) - 04:52, 10 April 2024
  • Thumbnail for Protease
    excessive protease-triggered activation of its own complement system), antithrombin (which protects the body from excessive coagulation), plasminogen activator...
    26 KB (2,799 words) - 15:02, 30 June 2024