• Thumbnail for Benzanilide
    Benzanilide is the organic compound with the formula C6H5C(O)NHC6H5. It is a white solid. Commercially available, it may be prepared by treating benzoic...
    2 KB (41 words) - 19:23, 5 June 2023
  • is named after Anton Vilsmeier and Albrecht Haack [de]. For example, benzanilide and dimethylaniline react with phosphorus oxychloride to produce an unsymmetrical...
    5 KB (457 words) - 18:59, 26 September 2024
  • Thumbnail for Anilide
    Herbicides Fungicides - Oxycarboxin, Carboxin Carl N. Webb (1941). "Benzanilide". Organic Syntheses; Collected Volumes, vol. 1, p. 82. "Anilide herbicides"...
    2 KB (141 words) - 00:50, 24 January 2023
  • Thumbnail for Schmidt reaction
    in 1924 by successfully converting benzophenone and hydrazoic acid to benzanilide. The intramolecular reaction was not reported until 1991 but has become...
    8 KB (909 words) - 14:03, 26 September 2024
  • Thumbnail for Suramin
    Suramin (category Benzanilides)
    Suramin is a medication used to treat African sleeping sickness and river blindness. It is the treatment of choice for sleeping sickness without central...
    23 KB (2,122 words) - 20:06, 9 October 2024
  • Thumbnail for Aniline
    York: Wiley-Interscience, ISBN 978-0-471-72091-1 Carl N. Webb (1941). "Benzanilide". Organic Syntheses; Collected Volumes, vol. 1, p. 82. Panda, Dr H (2019)...
    38 KB (4,052 words) - 14:06, 10 September 2024
  • Thumbnail for Imatinib
    Imatinib (category Benzanilides)
    Imatinib, sold under the brand names Gleevec and Glivec (both marketed worldwide by Novartis) among others, is an oral targeted therapy medication used...
    71 KB (6,702 words) - 05:32, 9 August 2024
  • Otilonium bromide (category Benzanilides)
    Otilonium bromide, sold under the trade name Spasmomen among others, is an antimuscarinic and calcium channel blocker used to relieve spasmodic pain of...
    5 KB (352 words) - 19:39, 24 June 2023
  • Thumbnail for Tolvaptan
    Tolvaptan (category Benzanilides)
    Tolvaptan, sold under the brand name Samsca among others, is an aquaretic drug that functions as a selective, competitive vasopressin receptor 2 (V2) antagonist...
    11 KB (763 words) - 16:45, 26 June 2024
  • Thumbnail for Mepronil
    Mepronil (category Benzanilides)
    Industries in 1981 using their brand name Basitac. The compound is a benzanilide which combines 2-methylbenzoic acid with the O-isopropyl derivative of...
    7 KB (618 words) - 11:38, 25 May 2024
  • Thumbnail for Nilotinib
    Nilotinib (category Benzanilides)
    Nilotinib, sold under the brand name Tasigna marketed worldwide by Novartis, is a medication used to treat chronic myelogenous leukemia (CML) which has...
    20 KB (1,697 words) - 00:44, 27 August 2024
  • Thumbnail for Succinate dehydrogenase
    basidiomycetes such as stem rusts and Rhizoctonia diseases. In the 1980s simple benzanilides were found to have comparable activity to carboxin and a number of these...
    27 KB (2,940 words) - 06:32, 3 October 2024
  • Thumbnail for Fominoben
    Fominoben (category Benzanilides)
    Fominoben is an antitussive agent of the benzanilide class, formerly marketed under the name Noleptan. It binds poorly to the sigma-1 receptor, a receptor...
    4 KB (279 words) - 08:49, 8 January 2024
  • Thumbnail for Vismodegib
    Vismodegib (category Benzanilides)
    Vismodegib, sold under the brand name Erivedge, is a medication used for the treatment of basal-cell carcinoma (BCC). The approval of vismodegib on January...
    7 KB (483 words) - 19:42, 20 December 2023
  • Law B, Major J, Plant H, Slater AM (September 2011), "The discovery of benzanilides as c-Met receptor tyrosine kinase inhibitors by a directed screening...
    32 KB (3,542 words) - 19:34, 2 July 2024
  • Thumbnail for Fostedil
    marketed. It has antihypertensive and antiarrhythmic effects. Treatment of benzanilide with phosphorus pentasulfide or Lawesson's reagent gives thioamide. Oxidative...
    4 KB (353 words) - 16:53, 15 August 2023
  • Thumbnail for Ebselen
    with 2-(chloroseleno)benzoyl chloride (Route I), by ortho-lithiation of benzanilides followed by oxidative cyclization (Route II) mediated by cupric bromide...
    10 KB (909 words) - 11:12, 10 October 2023
  • Thumbnail for Mozavaptan
    Mozavaptan (category Benzanilides)
    Mozavaptan (INN) is a vasopressin receptor antagonist marketed by Otsuka. In Japan, it was approved in October 2006 for hyponatremia (low blood sodium...
    3 KB (72 words) - 00:15, 5 November 2022
  • Thumbnail for Tolvaptan phosphate
    Tolvaptan phosphate (category Benzanilides)
    Tolvaptan phosphate is a drug used for the treatment of cardiac edema. It is a prodrug of tolvaptan, formulated as the salt tolvaptan sodium phosphate...
    5 KB (222 words) - 20:40, 22 November 2023
  • Thumbnail for Tariquidar
    Tariquidar (category Benzanilides)
    Tariquidar (INN/USAN) is a P-glycoprotein inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Robey RW, Shukla S, Finley...
    3 KB (79 words) - 13:29, 2 April 2023
  • Thumbnail for Encainide
    Encainide (category Benzanilides)
    Encainide (trade name Enkaid) is a class Ic antiarrhythmic agent. It is no longer used because of its frequent proarrhythmic side effects. Iferanserin...
    3 KB (113 words) - 16:37, 23 September 2024
  • Thumbnail for Mocetinostat
    Mocetinostat (category Benzanilides)
    Mocetinostat (MGCD0103) is a benzamide histone deacetylase inhibitor undergoing clinical trials for treatment of various cancers including follicular lymphoma...
    6 KB (378 words) - 09:05, 10 January 2024
  • Thumbnail for SB-216641
    SB-216641 (category Benzanilides)
    SB-216641 is a drug which is a selective antagonist for the serotonin receptor 5-HT1B, with around 25x selectivity over the closely related 5-HT1D receptor...
    4 KB (312 words) - 17:15, 29 September 2024
  • Thumbnail for GR-127935
    GR-127935 (category Benzanilides)
    GR-127935 is a drug which acts as a selective antagonist at the serotonin receptors 5-HT1B and 5-HT1D. It has little effect when given by itself but blocks...
    3 KB (226 words) - 12:59, 5 August 2024
  • Thumbnail for Ameltolide
    Ameltolide (category Benzanilides)
    Ameltolide, a 4-aminobenzamide derivative, is an experimental anticonvulsant agent, effective at inhibiting seizures in animal models. It is non-toxic...
    2 KB (109 words) - 12:38, 13 May 2023
  • Thumbnail for DPI-3290
    DPI-3290 (category Benzanilides)
    DPI-3290 was discovered by scientists at Burroughs Wellcome and licensed to Delta Pharmaceutical and is a drug that is used in scientific research. It...
    3 KB (249 words) - 12:15, 5 September 2024
  • Thumbnail for Ibrolipim
    Ibrolipim (category Benzanilides)
    Ibrolipim (NO-1886) is a cholesterol lowering drug from the statin family, which acts as a lipoprotein lipase activator. The discovery of the "statin"...
    2 KB (105 words) - 18:46, 30 January 2023
  • Thumbnail for Iobenzamic acid
    Iobenzamic acid (category Benzanilides)
    Iobenzamic acid is a pharmaceutical drug used as an X-ray contrast agent. It is a water-soluble, hepatotropic contrast medium, meaning it is taken up by...
    2 KB (60 words) - 17:42, 4 February 2024