CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a...
15 KB (1,738 words) - 05:58, 17 August 2024
infusion. The medication consists of a humanized monoclonal antibody against CD22 (inotuzumab), linked to a cytotoxic agent from the class of calicheamicins...
13 KB (1,246 words) - 02:44, 14 August 2024
An anti-CD22 immunotoxin is a monoclonal antibody targeting CD22 linked to a cytotoxic agent. As of August 2009, it was studied in the treatment of some...
9 KB (859 words) - 17:11, 13 September 2024
Moxetumomab pasudotox, sold under the brand name Lumoxiti, is an anti-CD22 immunotoxin medication for the treatment of adults with relapsed or refractory...
17 KB (1,438 words) - 04:13, 16 July 2024
endpoint. Epratuzumab binds to the glycoprotein CD22 of mature and malignant B-cells. Elevated CD22 and other B-cell receptor (BCR) proteins are associated...
5 KB (377 words) - 23:53, 14 June 2023
patients were treated with the recombinant immunotoxin which targets the CD22 cell surface receptor on these leukemic cells. In two uncontrolled clinical...
4 KB (573 words) - 11:44, 13 August 2023
Parallel studies by Ajit Varki and colleagues on the previously cloned CD22 (a B cell surface protein involved in adhesion and activation) showed direct...
35 KB (3,968 words) - 06:48, 16 September 2024
district RAND California Election Returns: District Definitions California Voter Foundation map - CD22 35°12′N 119°54′W / 35.2°N 119.9°W / 35.2; -119.9...
65 KB (792 words) - 04:29, 7 October 2024
B-cells based on their expression of B-cell marker proteins (e.g. CD20, CD19, CD22, CD79, PAX5, BOB1, OCT2, an immunoglobulin [usually IgM but occasionally...
69 KB (8,143 words) - 18:36, 22 January 2024
cell therapy targeting CD22 for the treatment of relapsed/refractory ALL and will be leading a trial using a combinatorial CD19/CD22 targeted CAR-T cell...
12 KB (1,198 words) - 16:53, 14 May 2024
monoclonal antibody, inotuzumab ozogamicin (marketed as Besponsa), an anti-CD22-directed antibody-drug conjugate, was approved by the U.S. Food and Drug...
16 KB (1,506 words) - 18:06, 10 February 2024
ATC code L01 Antineoplastic agents is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes...
12 KB (877 words) - 15:36, 25 January 2024
other small B-cell NHLs. B-cell-associated antigens such as CD19, CD20, CD22, and CD79a are usually expressed. In contrast to small lymphocytic lymphoma...
19 KB (2,138 words) - 02:22, 25 July 2024
M, Sato S (April 2007). "B cell signaling and autoimmune diseases: CD19/CD22 loop as a B cell signaling device to regulate the balance of autoimmunity"...
32 KB (3,916 words) - 10:07, 6 October 2024
differentiation, cell surface proteins – namely CD30, with CD19, CD20 and CD22, and with the absence of CD15. Other markers may also be used to confirm...
43 KB (5,063 words) - 02:46, 15 September 2024
T cell CD45+, CD3+, CD8+ B lymphocyte CD45+, CD19+, CD20+, CD24+, CD38, CD22 Thrombocyte CD45+, CD61+ Natural killer cell CD16+, CD56+, CD3-, CD31, CD30...
14 KB (1,368 words) - 17:53, 4 September 2024
CD8 a CD9 CD10 CD11 a b c d CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36...
33 KB (3,930 words) - 21:04, 3 September 2024
as a monotherapy for the treatment of adults with relapsed or refractory CD22-positive B-cell precursor acute lymphoblastic leukemia (ALL) on June 30,...
41 KB (4,305 words) - 11:56, 24 August 2024
for a chimeric antigen receptor (CAR-T) cell product candidate targeting CD22. In April 2015 the company entered into a collaboration with MedImmune (a...
9 KB (828 words) - 14:45, 24 September 2024
cadmium in a mixture of cadmium chloride and aluminium chloride, forming the Cd22+ cation, which is similar to the Hg22+ cation in mercury(I) chloride. Cd...
66 KB (7,364 words) - 18:14, 18 September 2024
phospho-proteins involved in hematopoietic cell signaling, (e.g., the LYN-CD22-SHP-1 pathway). Multiple alternatively spliced variants of this gene, which...
20 KB (2,292 words) - 02:56, 28 March 2024
67020 GBIF: 1237285 iNaturalist: 377629 IRMNG: 1335409 NCBI: 2877358 NZOR: b532eec5-cd22-4017-b56d-edaaf8829b87 Open Tree of Life: 4612255 WoRMS: 989807...
5 KB (422 words) - 21:58, 31 August 2024
AMIGO1 AMIGO2 AXL BCAM BOC BSG BTLA C10orf72 C20orf102 CADM1 CADM3 CD200 CD22 CD276 CD33 CD4 CDON CEACAM1 CEACAM16 CEACAM20 CEACAM21 CEACAM5 CEACAM6 CEACAM8...
6 KB (493 words) - 18:09, 13 July 2024
CD8 a CD9 CD10 CD11 a b c d CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36...
30 KB (3,464 words) - 22:51, 24 May 2024
CD8 a CD9 CD10 CD11 a b c d CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36...
12 KB (1,369 words) - 13:37, 10 May 2024
2007. The most promising seemed to be the anti-CD20 rituximab and the anti-CD22 epratuzumab, while the anti-TNF-α and IFN-α seemed less effective. In 2014...
86 KB (9,160 words) - 03:09, 6 October 2024
larger than normal and positive for CD19, CD20, CD22, CD11c, CD25, CD103, and FMC7 antigens. (CD103, CD22, and CD11c are strongly expressed.) Hairy cell...
57 KB (7,246 words) - 00:23, 27 June 2024
Immunological markers B cell Lineage T cell Lineage B cell lineage CD19, CD22, CD79a + − CD10 − or + (common ALL) cytoplasmic Ig − or + (pre-B ALL) surface...
78 KB (7,755 words) - 17:38, 17 September 2024
CD8 a CD9 CD10 CD11 a b c d CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36...
11 KB (1,311 words) - 20:50, 18 October 2022
from atypical/mixed CLL for the five markers' expression (CD5, CD23, FMC7, CD22, and immunoglobulin light chain) Matutes's CLL scoring system is very helpful...
73 KB (7,597 words) - 22:02, 28 August 2024