Eicosanoids are signaling molecules made by the enzymatic or non-enzymatic oxidation of arachidonic acid or other polyunsaturated fatty acids (PUFAs)...
86 KB (9,651 words) - 05:53, 21 September 2024
Nonclassic eicosanoids are biologically active signaling molecules made by oxygenation of twenty-carbon fatty acids other than the classic eicosanoids. "Eicosanoid"...
6 KB (556 words) - 02:37, 7 October 2021
Essential fatty acid interactions (category Eicosanoids)
along with the major eicosanoids from AA, EPA, and DGLA. Dietary ω-3 and GLA counter the inflammatory effects of AA's eicosanoids in three ways: displacement...
27 KB (2,975 words) - 17:27, 3 August 2024
Prostaglandins (PG) are a group of physiologically active lipid compounds called eicosanoids that have diverse hormone-like effects in animals. Prostaglandins have...
25 KB (2,453 words) - 09:31, 24 September 2024
In molecular biology the MAPEG (Membrane-Associated Proteins in Eicosanoid and Glutathione metabolism) family of proteins are a group of membrane associated...
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(also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation and is also...
20 KB (1,687 words) - 20:55, 12 September 2024
Most of the eicosanoid receptors are integral membrane protein G protein-coupled receptors (GPCRs) that bind and respond to eicosanoid signaling molecules...
24 KB (2,893 words) - 07:17, 15 May 2024
(when combatting bacterial infection for example) and pro-inflammatory eicosanoids have completed their function, healing proceeds in 4 phases. In the recall...
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release vasoactive amines such as histamine and serotonin, as well as eicosanoids such as prostaglandin E2 and leukotriene B4 to remodel the local vasculature...
94 KB (9,537 words) - 11:59, 30 September 2024
and oils. Examples of biologically important fatty acids include the eicosanoids, derived primarily from arachidonic acid and eicosapentaenoic acid, that...
71 KB (7,373 words) - 18:28, 13 September 2024
ω−6 strongly affects function. They are modified to make the classic eicosanoids (affecting inflammation and many other cellular functions) the endocannabinoids...
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inflammatory exudate for up to 15 hours, although there was less effect on eicosanoid production when compared to the effects produced by NSAIDs such as phenylbutazone...
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(ω-6). Eicosanoids, a diverse family of signaling molecules, are produced by oxygenation of polyunsaturated eicosatetraenoic acids. The eicosanoids, working...
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acids Glyco- sphingolipids Sphingolipids Waxes Polyunsaturated fatty acids Neurotransmitters & thyroid hormones Steroids Endo- cannabinoids Eicosanoids...
49 KB (5,447 words) - 09:39, 19 September 2024
contains 20 carbon atoms, including a 5-carbon ring. They are a subclass of eicosanoids and form the prostanoid class of fatty acid derivatives. The prostaglandins...
50 KB (5,561 words) - 07:03, 13 August 2024
preferentially produced by eosinophil peroxidase) Lipid mediators like the eicosanoids from the leukotriene (e.g., LTC4, LTD4, LTE4) and prostaglandin (e.g...
29 KB (3,166 words) - 00:19, 9 September 2024
synthesis. Lipocortin-1 both suppresses phospholipase A2, thereby blocking eicosanoid production, and inhibits various leukocyte inflammatory events (epithelial...
54 KB (5,544 words) - 02:02, 8 October 2024
infected tissues. By 1979, eicosanoids were further identified, including thromboxanes, prostacyclins, and leukotrienes. The eicosanoids typically have a short...
115 KB (12,761 words) - 02:00, 21 September 2024
acids Glyco- sphingolipids Sphingolipids Waxes Polyunsaturated fatty acids Neurotransmitters & thyroid hormones Steroids Endo- cannabinoids Eicosanoids...
30 KB (3,290 words) - 17:06, 4 October 2024
242) Pravadoline RCS-4 WIN 54,461 Cyclohexylphenols CP-47,947 CP-55,940 Eicosanoids AM-883 AM-1346 ACEA ACPA Methanandamide (AM-356) O-585 O-689 O-1812 O-1860...
124 KB (11,374 words) - 18:23, 14 October 2024
hydroxeicosatetraenoic acids, e.g. 18-HETE, 17-HETE, and 16-HETE, see eicosanoid and lipoxygenase pages. This disambiguation page lists articles associated...
543 bytes (92 words) - 20:34, 9 November 2022
Thromboxane (category Eicosanoids)
Thromboxane is a member of the family of lipids known as eicosanoids. The two major thromboxanes are thromboxane A2 and thromboxane B2. The distinguishing...
10 KB (1,144 words) - 03:09, 15 September 2024
acids Glyco- sphingolipids Sphingolipids Waxes Polyunsaturated fatty acids Neurotransmitters & thyroid hormones Steroids Endo- cannabinoids Eicosanoids...
88 KB (9,672 words) - 15:08, 30 September 2024
uncommon fatty acid, found only in trace amounts in animal products. The eicosanoid metabolites of DGLA are: Series-1 thromboxanes (thromboxanes with 1 double-bond)...
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242) Pravadoline RCS-4 WIN 54,461 Cyclohexylphenols CP-47,947 CP-55,940 Eicosanoids AM-883 AM-1346 ACEA ACPA Methanandamide (AM-356) O-585 O-689 O-1812 O-1860...
165 KB (17,242 words) - 10:41, 9 October 2024
(DHA) and eicosapentaenoic acid (EPA), which inhibits pro-inflammatory eicosanoids and cytokines (TNF-a, IL-1b and IL-6), decreasing both lymphocyte proliferation...
148 KB (16,086 words) - 19:54, 2 October 2024
Γ-Linolenic acid (section Source of eicosanoids)
dihomo-γ-linolenic acid (DGLA). This is one of the body's three sources of eicosanoids (along with AA and EPA.) DGLA is the precursor of the prostaglandin PGH1...
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Biomolecule families Carbohydrates: Alcohols Glycoproteins Glycosides Lipids: Eicosanoids Fatty acids Fatty-acid metabolism Glycerides Phospholipids Sphingolipids...
113 KB (12,407 words) - 18:55, 25 September 2024
activity in metabolizing arachidonic acid to the blood pressure-regulating eicosanoid, 20-hydroxyeicosatetraenoic acid. A study has shown that humans bearing...
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aminoalkylindoles, 1,5-diarylpyrazoles, quinolines, and arylsulfonamides as well as eicosanoids related to endocannabinoids. Medical uses include the treatment of nausea...
74 KB (7,813 words) - 19:14, 23 September 2024