• Thumbnail for GSK-3
    Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase that mediates the addition of phosphate molecules onto serine and threonine amino...
    49 KB (5,789 words) - 23:55, 29 August 2024
  • Thumbnail for Glycogen synthase kinase-3 beta
    Glycogen synthase kinase-3 beta, (GSK-3 beta), is an enzyme that in humans is encoded by the GSK3B gene. In mice, the enzyme is encoded by the Gsk3b gene...
    17 KB (1,819 words) - 16:52, 22 May 2024
  • Thumbnail for Glycogen synthase
    Glycogen synthase (UDP-glucose-glycogen glucosyltransferase) is a key enzyme in glycogenesis, the conversion of glucose into glycogen. It is a glycosyltransferase...
    16 KB (1,741 words) - 06:57, 18 December 2023
  • Thumbnail for Tideglusib
    (NP-12, NP031112) is a potent and irreversible small molecule glycogen synthase kinase 3 (GSK-3) inhibitor. There are few classes of GSK-inhibitors, including...
    8 KB (685 words) - 20:45, 29 August 2024
  • Thumbnail for Tau-protein kinase
    protein kinase PK40erk, cdk5/p20, CDK5/p23, glycogen synthase kinase-3beta, GSK, protein tau kinase, STK31, tau kinase, [tau-protein] kinase, tau-protein...
    4 KB (404 words) - 15:58, 26 August 2023
  • Thumbnail for Lithium (medication)
    depolarization. Lithium both directly and indirectly inhibits GSK3β (glycogen synthase kinase 3β) which results in the activation of mTOR. This leads to an increase...
    92 KB (9,852 words) - 18:28, 14 August 2024
  • Thumbnail for MTOR
    rapamycin with phosphoinositide 3-kinase signaling pathway regulates protein phosphatase 2A- and glycogen synthase kinase-3 -dependent phosphorylation of...
    119 KB (12,654 words) - 00:05, 31 July 2024
  • Thumbnail for GSK3A
    GSK3A (category Protein kinases)
    Glycogen synthase kinase-3 alpha is an enzyme that in humans is encoded by the GSK3A gene. Glycogen synthase kinase 3-alpha EC 2.7.1.37 is a multifunctional...
    2 KB (212 words) - 06:36, 18 December 2023
  • Thumbnail for Insulin receptor
    Insulin receptor (category Tyrosine kinase receptors)
    PKB also phosphorylates and inhibits glycogen synthase kinase, which is an enzyme that inhibits glycogen synthase. Therefore, PKB acts to start the process...
    31 KB (3,785 words) - 16:28, 25 May 2024
  • Thumbnail for Protein kinase A
    known as cAMP-dependent protein kinase (EC 2.7.11.11). PKA has several functions in the cell, including regulation of glycogen, sugar, and lipid metabolism...
    27 KB (2,665 words) - 17:03, 6 April 2024
  • to: Galatasaray S.K., a Turkish sports club based in Istanbul Glycogen synthase kinase Golden State Killer, a California serial rapist and murderer GSK...
    338 bytes (72 words) - 06:52, 10 June 2022
  • Thumbnail for CTP synthetase
    CTP synthetase (redirect from CTP synthase)
    by glycogen synthase kinase 3 (GSK3) in response to low serum conditions. Additionally, Ser568 has been seen to be phosphorylated by casein kinase 1,...
    18 KB (1,977 words) - 23:19, 2 September 2023
  • Thumbnail for Protein kinase B
    plasma membrane. Glycogen synthase kinase 3 (GSK-3) could be inhibited upon phosphorylation by Akt, which results in increase of glycogen synthesis. GSK3...
    35 KB (3,831 words) - 18:08, 20 August 2024
  • Thumbnail for Insulin
    also phosphorylates glycogen synthase kinase (GSK), thereby inactivating this enzyme. This means that its substrate, glycogen synthase (GS), cannot be phosphorylated...
    121 KB (13,799 words) - 18:32, 22 August 2024
  • phosphorylase kinase. This activates glycogen phosphorylase and inhibits glycogen synthase. Glycogenolysis Glycogen synthase Glycogen storage disease...
    5 KB (608 words) - 13:58, 23 August 2024
  • Thumbnail for Glycogen phosphorylase
    activates glycogen phosphorylase kinase. Glycogen phosphorylase kinase activates glycogen phosphorylase in the same manner mentioned previously. Glycogen phosphorylase...
    26 KB (2,918 words) - 13:58, 23 August 2024
  • Thumbnail for Catenin beta-1
    capable to bind β-TrCP. Phosphorylation of the motif is performed by Glycogen Synthase Kinase 3 alpha and beta (GSK3α and GSK3β). GSK3s are constitutively active...
    107 KB (12,362 words) - 22:48, 10 July 2024
  • "Protein Kinase A Negatively Modulates the Nuclear Accumulation of NF-ATc1 by Priming for Subsequent Phosphorylation by Glycogen Synthase Kinase-3", The...
    45 KB (4,088 words) - 03:19, 30 July 2024
  • Thumbnail for Serine/threonine-specific protein kinase
    A serine/threonine protein kinase (EC 2.7.11.-) is a kinase enzyme, in particular a protein kinase, that phosphorylates the OH group of the amino-acid...
    14 KB (1,210 words) - 13:35, 14 June 2024
  • 2.125. Li X, Liu M, Cai Z, Wang G, Li X (2010). "Regulation of glycogen synthase kinase-3 during bipolar mania treatment". Bipolar Disord. 12 (7): 741–52...
    51 KB (5,619 words) - 23:00, 22 August 2024
  • Thumbnail for Glycogen storage disease
    / GSD9C / GSD9D. GSD type 0: Although glycogen synthase deficiency does not result in storage of extra glycogen in the liver, it is classified with the...
    68 KB (6,092 words) - 22:40, 28 August 2024
  • Thumbnail for Protein phosphorylation
    Burgering BM (May 1998). "Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative...
    67 KB (7,955 words) - 20:50, 29 July 2024
  • M500329-JLR200. PMID 16520488. Li T, Paudel HK (March 2006). "Glycogen synthase kinase 3beta phosphorylates Alzheimer's disease-specific Ser396 of...
    25 KB (3,066 words) - 02:55, 11 July 2024
  • Thumbnail for Ketamine
    tropomyosin receptor kinase B (TrkB), activation of the mammalian target of rapamycin (mTOR) pathway, deactivation of glycogen synthase kinase 3 (GSK-3), and...
    118 KB (11,362 words) - 03:08, 29 August 2024
  • Thumbnail for Lipid emulsion
    at the mitochondria. The Akt and ERK pathways converge to alter glycogen synthase kinase-3 beta (GSK-3β) activity. Specifically, Akt and ERK phosphorylate...
    12 KB (1,502 words) - 17:45, 10 June 2024
  • Thumbnail for Ribosomal s6 kinase
    Cytosolic substrates of p90rsk include protein phosphatase 1; glycogen synthase kinase 3 (GSK3); L1 CAM, a neural cell adhesion molecule; Son of Sevenless...
    5 KB (510 words) - 17:10, 16 September 2021
  • mammalian target of rapamycin (mTOR), glycogen synthase kinase-3 (GSK3), and elongation factor 2 (eEF2) kinase. Ketamine has also demonstrated its ability...
    21 KB (2,363 words) - 14:52, 21 August 2024
  • Thumbnail for Cyclin D
    et al. (October 2000). "The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding...
    39 KB (4,605 words) - 22:37, 27 March 2024
  • PI3K/Akt pathway. It does so by activating Akt while inactivating glycogen synthase kinase-3β (GSK-3β), an inhibitor of the Akt pathway. Emodin specifically...
    9 KB (952 words) - 11:12, 20 May 2024
  • Thumbnail for Myelin
    myelination during development and myelin repair in older age. Glycogen synthase kinase 3β inhibitors such as lithium chloride have been found to promote...
    33 KB (4,053 words) - 14:01, 12 July 2024