• Thumbnail for Hepatocyte
    A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 80% of the liver's mass. These cells are involved in: Protein...
    14 KB (1,621 words) - 06:14, 20 August 2024
  • Thumbnail for Hepatocyte growth factor
    Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells...
    23 KB (2,635 words) - 06:03, 24 August 2024
  • Thumbnail for Hepatocyte growth factor receptor
    Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity...
    59 KB (6,727 words) - 06:01, 27 October 2024
  • Thumbnail for Ballooning degeneration
    degeneration, formally ballooning degeneration of hepatocytes, is a form of liver parenchymal cell (i.e. hepatocyte) death. The name is derived from the fact...
    3 KB (332 words) - 21:11, 13 June 2024
  • Thumbnail for Ground glass hepatocyte
    In liver pathology, a ground glass hepatocyte, abbreviated GGH, is a liver parenchymal cell with a flat hazy and uniformly dull appearing cytoplasm on...
    4 KB (398 words) - 08:37, 10 June 2024
  • Hepatocyte nuclear factors (HNFs) are a group of phylogenetically unrelated transcription factors that regulate the transcription of a diverse group of...
    8 KB (585 words) - 20:31, 30 May 2024
  • Thumbnail for Feathery degeneration
    degeneration, formally feathery degeneration of hepatocytes, is a form of liver parenchymal cell (i.e. hepatocyte) death associated with cholestasis. Cells...
    2 KB (132 words) - 21:12, 29 July 2023
  • Thumbnail for Hepatocyte nuclear factor 4 alpha
    Hepatocyte nuclear factor 4 alpha (HNF4A) also known as NR2A1 (nuclear receptor subfamily 2, group A, member 1) is a nuclear receptor that in humans is...
    18 KB (2,230 words) - 15:35, 22 August 2024
  • When hepatocytes cannot proliferate, biliary epithelial cells are capable of turning into hepatocytes. The reverse can also occur, with hepatocytes turning...
    22 KB (2,475 words) - 05:46, 24 September 2024
  • Thumbnail for Dihexa
    oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met...
    7 KB (492 words) - 08:38, 3 October 2024
  • Thumbnail for Alcoholic hepatitis
    hepatitis also leads to impaired hepatocyte differentiation, impairments in hepatocyte regeneration and hepatocyte de-differentiation into cholangiocyte...
    21 KB (2,285 words) - 17:37, 21 October 2024
  • Thumbnail for Hepatocyte nuclear factor 4 gamma
    Hepatocyte nuclear factor 4 gamma (HNF4G) also known as NR2A2 (nuclear receptor subfamily 2, group A, member 2) is a nuclear receptor that in humans is...
    4 KB (417 words) - 13:51, 10 July 2024
  • Thumbnail for Perisinusoidal space
    Disse) is a space between a hepatocyte, and a sinusoid in the liver. It contains the blood plasma. Microvilli of hepatocytes extend into this space, allowing...
    4 KB (383 words) - 09:10, 29 September 2024
  • Thumbnail for MST1
    Macrophage-stimulating protein (MSP), also known as hepatocyte growth factor-like protein (HLP, HGFL, or HGFLP), is a protein that in humans is encoded...
    7 KB (901 words) - 22:17, 3 March 2023
  • HNF4 (Hepatocyte Nuclear Factor 4) is a nuclear receptor protein mostly expressed in the liver, gut, kidney, and pancreatic beta cells that is critical...
    5 KB (533 words) - 12:18, 21 October 2024
  • Thumbnail for Cholestasis
    hepatocytes. Bile infarcts are marked by a large amount of pigmented tissue surrounded by a ring of necrotic hepatocytes. In some cases, hepatocyte degeneration...
    112 KB (12,705 words) - 07:14, 11 September 2024
  • Thumbnail for Liver
    digestion. The liver's highly specialized tissue, consisting mostly of hepatocytes, regulates a wide variety of high-volume biochemical reactions, including...
    87 KB (10,331 words) - 07:56, 1 November 2024
  • Thumbnail for Hep G2
    model system for the study of polarized human hepatocytes. Another well-characterized polarized hepatocyte cell line is the rat hepatoma-derived hybrid...
    5 KB (577 words) - 05:27, 3 January 2023
  • Thumbnail for HNF1B
    homeobox B (hepatocyte nuclear factor 1 homeobox B), also known as HNF1B or transcription factor 2 (TCF2), is a human gene. HNF1B encodes hepatocyte nuclear...
    9 KB (1,254 words) - 20:30, 30 May 2024
  • performed analysis on transaminases in 1957. The proportion of AST to ALT in hepatocytes is about 2.5:1, but because AST is removed from serum by the liver sinusoidal...
    9 KB (974 words) - 04:11, 1 July 2024
  • Thumbnail for HepaRG
    injury. The HepaRG model is considered a surrogate for Primary Human Hepatocytes, which are the most pertinent model to reproduce the human liver functioning...
    25 KB (2,666 words) - 15:23, 29 June 2024
  • Thumbnail for Bile canaliculus
    called bile capillaries) is a thin tube that collects bile secreted by hepatocytes. The bile canaliculi empty into a series of progressively larger bile...
    1 KB (141 words) - 15:35, 11 February 2024
  • in charge of almost all the body’s metabolism. Main liver cells are hepatocytes, Kupffer cells, and hepatic stellate cells; each one with a specific...
    9 KB (1,239 words) - 16:34, 15 August 2024
  • with liver regeneration, with a specific focus on the significance of hepatocyte growth factor (HGF) and its receptor (MET), as well as the role of the...
    25 KB (2,734 words) - 13:16, 28 June 2024
  • mellitus. Oxytocin (OXT) Omentin Endothelin-1 Nesfatin-1 Irisin Betatrophin Hepatocyte growth factor (HGF) Fibroblast growth factor -Biomarkers with insulin-sensitizing...
    17 KB (2,133 words) - 18:38, 20 August 2024
  • Thumbnail for Madin-Darby canine kidney cells
    was shown to be a previously described protein secreted by fibroblasts, hepatocyte growth factor (HGF). This work solved an outstanding mystery of MDCK culture...
    22 KB (2,658 words) - 16:02, 7 April 2024
  • Thumbnail for Mammal
    (February 1985). "Ultraviolet light-induced DNA repair synthesis in hepatocytes from species of differing longevities". Mechanisms of Ageing and Development...
    222 KB (23,165 words) - 00:45, 27 October 2024
  • Thumbnail for 2C-B
    Mice hepatocytes produce 4-bromo-2,5-dimethoxy-phenol (BDMP), a previously unknown metabolite. Meanwhile, human, monkey and rabbit hepatocytes produce...
    38 KB (4,198 words) - 06:35, 6 October 2024
  • Thumbnail for Glycogenolysis
    membrane, and is therefore used solely by the myocytes that produce it. In hepatocytes (liver cells), the main purpose of the breakdown of glycogen is for the...
    6 KB (673 words) - 15:36, 24 October 2024
  • Thumbnail for Keratin
    cytoskeleton organization KRT18 extrinsic apoptotic signaling pathway KRT18 hepatocyte apoptotic process KRT18 cell-cell adhesion KRT19 Notch signaling pathway...
    39 KB (3,017 words) - 13:44, 1 September 2024