• Thumbnail for Melanocyte
    Melanocytes are melanin-producing neural crest-derived cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer...
    20 KB (2,274 words) - 09:10, 28 July 2024
  • neuropeptides consisting of α-melanocyte-stimulating hormone (α-MSH), β-melanocyte-stimulating hormone (β-MSH), and γ-melanocyte-stimulating hormone (γ-MSH)...
    10 KB (940 words) - 05:25, 31 October 2023
  • α-Melanocyte-stimulating hormone (α-MSH) is an endogenous peptide hormone and neuropeptide of the melanocortin family, with a tridecapeptide structure...
    8 KB (456 words) - 17:58, 15 September 2024
  • Thumbnail for Melanocyte-inhibiting factor
    Melanocyte-inhibiting factor (also known as Pro-Leu-Gly-NH2, Melanostatin, MSH release–inhibiting hormone or MIF-1) is an endogenous peptide fragment derived...
    17 KB (1,892 words) - 23:03, 6 August 2024
  • Thumbnail for Vitiligo
    produced by skin cells called melanocytes. Variations in genes that are part of the immune system or part of melanocytes have both been associated with...
    42 KB (4,423 words) - 08:11, 11 October 2024
  • Thumbnail for Lentigo
    harmless (benign) hyperplasia of melanocytes which is linear in its spread. This means the hyperplasia of melanocytes is restricted to the cell layer directly...
    6 KB (604 words) - 16:35, 27 January 2024
  • Thumbnail for Acral lentiginous melanoma
    Melanoma is a group of serious skin cancers that arise from pigment cells (melanocytes); acral lentiginous melanoma is a kind of lentiginous skin melanoma....
    15 KB (1,427 words) - 19:06, 3 September 2024
  • Thumbnail for Pituitary gland
    secreting prolactin). The intermediate lobe synthesizes and secretes melanocyte-stimulating hormone. The posterior pituitary (or neurohypophysis) is a...
    25 KB (2,790 words) - 14:46, 29 September 2024
  • Thumbnail for Freckle
    an increased number of the melanin-producing cells, or melanocytes, but instead have melanocytes that overproduce melanin granules (melanosomes) changing...
    11 KB (1,293 words) - 16:54, 4 September 2024
  • Thumbnail for Tortoiseshell cat
    extreme case, no melanocytes make it to the skin and the cat is entirely white (but not an albino). In intermediate cases, melanocyte migration is slowed...
    18 KB (2,044 words) - 23:00, 20 August 2024
  • Thumbnail for Heterochromia iridum
    heterochromia. Piebaldism – similar to Waardenburg's syndrome, a rare disorder of melanocyte development characterized by a white forelock and multiple symmetrical...
    26 KB (2,873 words) - 21:06, 1 October 2024
  • Thumbnail for Skin whitening
    of which CREB is a transcription factor. Alpha-melanocyte stimulating hormone (α-MSH), beta-melanocyte stimulating hormone (β-MSH), and adrenocorticotropic...
    67 KB (7,644 words) - 13:03, 4 October 2024
  • release in hair follicles. This overproduction causes depletion of the melanocyte stem cells which are required to produce melanin, the pigment responsible...
    6 KB (728 words) - 03:48, 19 September 2024
  • Thumbnail for Poliosis
    poliosis is marked by the lack of melanin or melanocytes in the hair bulbs, though epidermal melanocytes typically remain unaffected unless associated...
    11 KB (1,037 words) - 05:27, 27 September 2024
  • Thumbnail for Blue nevus
    nevus (also known as an "acquired dermal melanocytosis", and "dermal melanocyte hamartoma") is a cutaneous condition characterized by a diffusely gray-blue...
    6 KB (488 words) - 21:51, 12 September 2024
  • Thumbnail for Keratinocyte
    containing the endogenous photoprotectant melanin, from epidermal melanocytes. Each melanocyte in the epidermis has several dendrites that stretch out to connect...
    25 KB (2,752 words) - 22:34, 25 April 2024
  • Thumbnail for Β-Melanocyte-stimulating hormone
    β-Melanocyte-stimulating hormone (β-MSH) is an endogenous peptide hormone and neuropeptide. It is a melanocortin, specifically, one of the three types...
    3 KB (245 words) - 18:24, 15 September 2024
  • Thumbnail for Greying of hair
    of hair follicles produce melanocytes, the cells that produce and store pigment in hair and skin. The death of the melanocyte stem cells causes the onset...
    16 KB (1,854 words) - 11:53, 6 October 2024
  • Thumbnail for Melanin
    Melanin pigments are produced in a specialized group of cells known as melanocytes. There are five basic types of melanin: eumelanin, pheomelanin, neuromelanin...
    64 KB (6,759 words) - 04:33, 24 September 2024
  • Thumbnail for Grey
    specialized cell, the melanocyte, which is found in each hair follicle, from which the hair grows. As hair grows, the melanocyte injects melanin into the...
    30 KB (3,724 words) - 22:04, 5 October 2024
  • Melanosomes are synthesised in the skin in melanocyte cells, as well as the eye in choroidal melanocytes and retinal pigment epithelial (RPE) cells....
    11 KB (1,183 words) - 06:09, 10 June 2024
  • Thumbnail for Amelanism
    are phaeomelanosomes. Melanocyte-stimulating hormone (MSH) binds to the Melanocortin 1 receptor (MC1R) and commits melanocytes to the production of eumelanin...
    14 KB (1,537 words) - 21:02, 20 September 2023
  • γ-Melanocyte-stimulating hormone (γ-MSH) is an endogenous peptide hormone and neuropeptide. It is a melanocortin, specifically, one of the three types...
    4 KB (261 words) - 18:52, 15 September 2024
  • Thumbnail for Melanocytic nevus
    pigmented growth on the skin, formed mostly of a type of cell known as a melanocyte. The high concentration of the body's pigmenting agent, melanin, is responsible...
    28 KB (3,037 words) - 05:00, 7 August 2024
  • Thumbnail for Piebaldism
    melanin-forming cells (melanocytes) in certain areas of the skin and hair. It is a rare autosomal dominant disorder of melanocyte development.: 867  Common...
    8 KB (836 words) - 17:07, 1 January 2024
  • Thumbnail for Melanocortin 1 receptor
    The melanocortin 1 receptor (MC1R), also known as melanocyte-stimulating hormone receptor (MSHR), melanin-activating peptide receptor, or melanotropin...
    33 KB (3,769 words) - 04:57, 6 May 2024
  • Thumbnail for Radical surgery
    Immunohistochemistry with SOX10 (staining the cell nuclei of melanocytes) of lentigo maligna, showing malignant melanocytes all the way to the resection margin (inked in...
    2 KB (173 words) - 00:19, 5 March 2024
  • Thumbnail for Lentigo maligna
    Lentigo maligna is where melanocyte cells have become malignant and grow continuously along the stratum basale of the skin, but have not invaded below...
    11 KB (1,307 words) - 06:51, 15 April 2024
  • Thumbnail for Zinc
    of PARP-dependent energy crisis in cultured human keratinocytes and melanocytes. In 1982, the US Mint began minting pennies coated in copper but containing...
    143 KB (16,228 words) - 07:01, 9 October 2024
  • Thumbnail for Human skin color
    pigment melanin. Melanin is produced within the skin in cells called melanocytes and it is the main determinant of the skin color of darker-skin humans...
    129 KB (14,413 words) - 19:17, 7 October 2024