• The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide, referring to...
    7 KB (751 words) - 22:09, 29 July 2024
  • group, the C-terminus, and an end with an unbound amine group, the N-terminus. Proteins are naturally synthesized starting from the N-terminus and ending...
    5 KB (583 words) - 18:03, 18 April 2024
  • Thumbnail for Ubiquitin
    threonine residues through an ester bond, or the amino group of the protein's N-terminus via a peptide bond. The protein modifications can be either a single ubiquitin...
    98 KB (11,068 words) - 18:25, 16 July 2024
  • Thumbnail for Post-translational modification
    O-acylation (esters), N-acylation (amides), S-acylation (thioesters) acetylation, the addition of an acetyl group, either at the N-terminus of the protein or...
    33 KB (3,189 words) - 03:12, 28 March 2024
  • Thumbnail for Protein
    as the N-terminus or amino terminus, whereas the end of the protein with a free carboxyl group is known as the C-terminus or carboxy terminus (the sequence...
    102 KB (11,357 words) - 18:03, 29 July 2024
  • Thumbnail for XPG N terminus
    molecular biology the protein domain XPG refers to, in this case, the N-terminus of XPG. The XPG protein can be corrected by a 133 kDa nuclear protein...
    5 KB (559 words) - 03:21, 29 November 2023
  • myristoyl group at the N-terminus being able to covalently attach to the membranes. Other amino acid residues at the N-terminus are important for membrane...
    10 KB (1,215 words) - 03:15, 19 April 2024
  • bond to the C-terminus, but entropically it was more favorable to hydrogen bond with the N-terminus. Specifically, they found that C-terminus hydrogen bonding...
    22 KB (3,074 words) - 18:57, 8 July 2024
  • (usually 16-30 amino acids long) present at the N-terminus (or occasionally nonclassically at the C-terminus or internally) of most newly synthesized proteins...
    15 KB (1,741 words) - 18:05, 31 December 2023
  • Thumbnail for Protein primary structure
    in the opposite order (starting at the C-terminus) to biological protein synthesis (starting at the N-terminus). Protein sequence is typically notated...
    21 KB (2,595 words) - 15:26, 27 May 2024
  • Thumbnail for N,N'-Dicyclohexylcarbodiimide
    DMAP. In protein synthesis (such as Fmoc solid-state synthesizers), the N-terminus is often used as the attachment site on which the amino acid monomers...
    14 KB (1,191 words) - 13:39, 7 July 2024
  • Western blotting. The peptide sequence of the FLAG-tag from the N-terminus to the C-terminus is: DYKDDDDK (1012 Da). Additionally, FLAG-tags may be used in...
    7 KB (846 words) - 23:15, 23 May 2024
  • the N-terminus glycosylations that occur post-translation and contribute to an increase in apparent size of the mature receptor. The amino terminus of...
    8 KB (963 words) - 00:05, 3 April 2024
  • Thumbnail for Chhatrapati Shivaji Terminus
    Chhatrapati Shivaji Terminus (officially Chhatrapati Shivaji Maharaj Terminus since 2017, formerly Victoria Terminus (VT), Bombay station code: CSMT (mainline)/ST...
    24 KB (2,167 words) - 06:51, 26 July 2024
  • Thumbnail for Protein sequencing
    Edman degradation remains a valuable tool for characterizing a protein's N-terminus. It is often desirable to know the unordered amino acid composition of...
    21 KB (2,836 words) - 10:57, 8 February 2024
  • Thumbnail for Arginylation
    fully intact proteins, not just on the N-terminus of protein fragments or pre-processed proteins. In 1986, the N-end rule was elucidated, and it states...
    21 KB (2,495 words) - 23:15, 20 February 2024
  • Thumbnail for Peptide synthesis
    starts at the carboxyl end of the peptide (C-terminus), and proceeds toward the amino-terminus (N-terminus). Protein biosynthesis (long peptides) in living...
    51 KB (5,773 words) - 14:34, 7 June 2024
  • Thumbnail for Angiotensin
    other proteins of the serpin family, but angiotensinogen has an elongated N-terminus compared to other serpin family proteins. Obtaining actual crystals for...
    28 KB (3,125 words) - 13:46, 21 July 2024
  • Thumbnail for G protein-coupled receptor
    seven-transmembrane receptors. Ligands can bind either to the extracellular N-terminus and loops (e.g. glutamate receptors) or to the binding site within transmembrane...
    82 KB (9,384 words) - 18:56, 11 June 2024
  • Thumbnail for Integral membrane protein
    positioned such that their carboxyl-terminus is towards the cytosol, or Type II, which have their amino-terminus towards the cytosol. Type III proteins...
    9 KB (1,035 words) - 19:59, 25 January 2024
  • Thumbnail for Directionality (molecular biology)
    a 5′-to-3′ direction, and will extend the protein from its N-terminus toward its C-terminus. For example, in a typical gene a start codon (5′-ATG-3′) is...
    9 KB (1,191 words) - 13:38, 29 May 2024
  • Thumbnail for Teriparatide
    Forteo, is a form of parathyroid hormone (PTH) consisting of the first (N-terminus) 34 amino acids, which is the bioactive portion of the hormone. It is...
    27 KB (2,054 words) - 06:31, 7 July 2024
  • Thumbnail for Z-DNA
    to the E3L protein that determine virulence are the N-terminus and the C-terminus. The N-terminus is made of up a sequence similar to that of the Zα domain...
    34 KB (4,308 words) - 22:59, 25 November 2023
  • atomic mass and has 10 amino acids. It can be fused to the C-terminus and the N-terminus of a protein. It is advisable not to fuse the myc-tag directly...
    2 KB (296 words) - 22:15, 4 April 2024
  • Thumbnail for Phage display
    (within the N2 domain) and at the N-terminus (inserted between the N-terminal secretion sequence and the N-terminus of pIII). However, when using the...
    38 KB (4,630 words) - 03:13, 22 June 2024
  • mitochondrial matrix have specific signal sequences at their beginning (N-terminus) that consist of a string of 20 to 50 amino acids. These sequences are...
    52 KB (6,394 words) - 03:48, 19 March 2024
  • Thumbnail for Annexin
    amino (N)-terminus. The annexin core is highly conserved across the annexin family and the N-terminus varies greatly. The variability of the N-terminus is...
    28 KB (3,526 words) - 09:12, 10 June 2024
  • sequence ("arginine 3"), and also has an additional 13 amino acids at its N-terminus (MFPAMPLLSLFVN) ("long"), for a total of 83 amino acids (relative to the...
    5 KB (412 words) - 23:17, 19 June 2023
  • Thumbnail for Pyroglutamic acid
    pyroglutamic acid. The enzyme pyroglutamate aminopeptidase can restore a free N-terminus by cleaving off the pyroglutamate residue. Pyroglutamic acid exists as...
    10 KB (786 words) - 12:06, 12 April 2024
  • Thumbnail for Beta sheet
    Because peptide chains have a directionality conferred by their N-terminus and C-terminus, β-strands too can be said to be directional. They are usually...
    26 KB (3,100 words) - 18:37, 22 December 2023