• Thumbnail for P53
    p53, also known as Tumor protein P53, cellular tumor antigen p53 (UniProt name), or transformation-related protein 53 (TRP53) is a regulatory protein that...
    127 KB (13,339 words) - 03:27, 2 December 2024
  • p53 is a tumor suppressor protein. P53 may also refer to: p53 (band), an experimental music group p53 (album), their 1996 live album Curtiss XP-53, an...
    616 bytes (115 words) - 22:50, 23 October 2022
  • Thumbnail for Pattern 1853 Enfield
    Enfield Pattern 1853 rifle-musket (also known as the Pattern 1853 Enfield, P53 Enfield, and Enfield rifle-musket) was a .577 calibre MiniƩ-type muzzle-loading...
    17 KB (2,303 words) - 06:15, 12 November 2024
  • Thumbnail for INS Savitri (P53)
    INS Savitri (P53) is a Sukanya class patrol vessel of the Indian Navy. Wikimedia Commons has media related to INS Savitri (P53). "Surface Ships of Indian...
    2 KB (45 words) - 08:03, 23 August 2022
  • Thumbnail for Tumor suppressor gene
    as certain mutations in the p53 gene product. p53 mutations can function as a dominant negative, meaning that a mutated p53 protein can prevent the function...
    30 KB (3,409 words) - 03:26, 14 November 2024
  • Thumbnail for Mdm2
    p53 tumor suppressor. Mdm2 protein functions both as an E3 ubiquitin ligase that recognizes the N-terminal trans-activation domain (TAD) of the p53 tumor...
    34 KB (4,010 words) - 17:12, 19 August 2024
  • suppressor, p53. p53 is an apoptosis transcription factor normally found in the cytosol. When cellular DNA is damaged beyond repair, p53 is transported...
    42 KB (4,944 words) - 11:56, 4 April 2024
  • p53 was an experimental music group commissioned by English percussionist Chris Cutler to play at the 25th Frankfurt Jazz Festival in Germany in September...
    8 KB (754 words) - 12:55, 6 April 2024
  • p53 is a 1996 live album by experimental music group p53. It was their debut album and was recorded at the 25th Frankfurt Jazz Festival in Germany on 16...
    6 KB (522 words) - 05:01, 20 January 2021
  • Thumbnail for Cell division
    cyclin-CDK complexes. The p53 tumor-suppressor protein plays a crucial role at the G1/S checkpoint and the G2/M checkpoint. Activated p53 proteins result in...
    41 KB (4,735 words) - 04:45, 17 December 2024
  • gene. It consists of recombinant adenovirus engineered to code for p53 protein (rAd-p53) and is manufactured by Shenzhen SiBiono GeneTech. Gendicine was...
    7 KB (447 words) - 06:36, 11 October 2024
  • Thumbnail for P53 upregulated modulator of apoptosis
    The p53 upregulated modulator of apoptosis (PUMA) also known as Bcl-2-binding component 3 (BBC3), is a pro-apoptotic protein, member of the Bcl-2 protein...
    28 KB (3,387 words) - 06:12, 27 December 2023
  • Thumbnail for Oncovirus
    tumor proteins p53 and the retinoblastoma proteins (Rb). It is evolutionarily advantageous for viruses to inactivate p53 because p53 can trigger cell...
    52 KB (6,092 words) - 07:15, 10 December 2024
  • Thumbnail for P21
    primarily associated with inhibition of CDK2. p21 represents a major target of p53 activity and thus is associated with linking DNA damage to cell cycle arrest...
    34 KB (3,978 words) - 08:00, 23 February 2024
  • The p53 p63 p73 family is a family of tumor suppressor genes. This gene family codes the proteins: p53 TP73L (also known as "p63") p73 They are sometimes...
    4 KB (469 words) - 10:59, 23 December 2023
  • Thumbnail for Transversion
    respectively. The mutation of the P53 gene is the most common gene mutation found in cancer cells. A study has shown that p53 mutations are common in tobacco-related...
    7 KB (745 words) - 01:39, 4 August 2024
  • Thumbnail for TP53BP1
    Tumor suppressor p53-binding protein 1 also known as p53-binding protein 1 or 53BP1 is a protein that in humans is encoded by the TP53BP1 gene. 53BP1...
    15 KB (1,857 words) - 04:37, 2 December 2024
  • P53 regulation associated lncRNA is a protein that in humans is encoded by the PRAL gene. "Human PubMed Reference:". National Center for Biotechnology...
    408 bytes (43 words) - 17:51, 8 November 2024
  • Thumbnail for ThinkPad P series
    processors and Nvidia Quadro Pascal-based graphics. A redesign of the P52, the P53 features a 4K UHD OLED Touch display, Wi-Fi 6, Intel 9th Gen Coffee Lake...
    76 KB (1,998 words) - 14:05, 15 December 2024
  • Thumbnail for G1/S transition
    S phase. The G1/S transition is highly regulated by transcription factor p53 in order to halt the cell cycle when DNA is damaged. It is a "point of no...
    17 KB (2,136 words) - 14:28, 17 December 2024
  • and post-translational modification of proteins, for example, histones, p53, and tubulins. Among these proteins, chromatin proteins and metabolic enzymes...
    42 KB (4,895 words) - 08:33, 15 January 2024
  • P53-responsive gene 1 is a protein that in humans is encoded by the PRG1 gene. "Human PubMed Reference:". National Center for Biotechnology Information...
    2 KB (238 words) - 15:56, 12 August 2023
  • P53 road is a regional road (P-Highway) in Zakarpattia Oblast, Ukraine. It runs north-south and connects Malyi Bereznyi with a Slovakia-Ukraine border...
    2 KB (85 words) - 18:57, 15 July 2022
  • Thumbnail for Cyclin B
    cyclin B and the tumor suppressor gene p53. In general levels of p53 and cyclin B are negatively correlated. When p53 build-up triggers cell cycle arrest...
    11 KB (1,334 words) - 23:16, 17 December 2024
  • Thumbnail for 2-Imidazoline
    antagonists of MDM2. These compounds bind MDM2/X in the p53-binding pocket and activate the p53 pathway in cancer cells, leading to cell cycle arrest,...
    10 KB (902 words) - 20:21, 28 August 2022
  • Thumbnail for Apoptosis
    induce transcription of the p53 gene, resulting in the increase of p53 protein level and enhancement of cancer cell-apoptosis. p53 prevents the cell from replicating...
    91 KB (10,621 words) - 14:34, 6 December 2024
  • Thumbnail for USP7
    tumor suppressor protein, p53. Normally, p53 levels are kept low in part due to Mdm2-mediated ubiquitylation and degradation of p53. In response to oncogenic...
    19 KB (2,276 words) - 18:30, 20 September 2024
  • Thumbnail for Nutlin
    analogs which inhibit the interaction between mdm2 and tumor suppressor p53, and which were discovered by screening a chemical library by Vassilev et...
    6 KB (603 words) - 02:44, 3 December 2024
  • Thumbnail for Heterogeneous ribonucleoprotein particle
    coordination with p53. hnRNP K is rapidly induced after DNA damage by ionizing radiation. It cooperates with p53 to induce the activation of p53 target genes...
    17 KB (2,057 words) - 19:45, 8 December 2024
  • Thumbnail for SV40
    SV40 is an abbreviation for simian vacuolating virus 40 or simian virus 40, a polyomavirus that is found in both monkeys and humans. Like other polyomaviruses...
    19 KB (2,247 words) - 15:34, 14 December 2024