p53, also known as Tumor protein P53, cellular tumor antigen p53 (UniProt name), or transformation-related protein 53 (TRP53) is a regulatory protein that...
127 KB (13,339 words) - 03:27, 2 December 2024
p53 is a tumor suppressor protein. P53 may also refer to: p53 (band), an experimental music group p53 (album), their 1996 live album Curtiss XP-53, an...
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Pattern 1853 Enfield (redirect from P53 Enfield)
Enfield Pattern 1853 rifle-musket (also known as the Pattern 1853 Enfield, P53 Enfield, and Enfield rifle-musket) was a .577 calibre MiniƩ-type muzzle-loading...
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INS Savitri (P53) is a Sukanya class patrol vessel of the Indian Navy. Wikimedia Commons has media related to INS Savitri (P53). "Surface Ships of Indian...
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as certain mutations in the p53 gene product. p53 mutations can function as a dominant negative, meaning that a mutated p53 protein can prevent the function...
30 KB (3,409 words) - 03:26, 14 November 2024
Mdm2 (section Ubiquitination target: p53)
p53 tumor suppressor. Mdm2 protein functions both as an E3 ubiquitin ligase that recognizes the N-terminal trans-activation domain (TAD) of the p53 tumor...
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suppressor, p53. p53 is an apoptosis transcription factor normally found in the cytosol. When cellular DNA is damaged beyond repair, p53 is transported...
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p53 was an experimental music group commissioned by English percussionist Chris Cutler to play at the 25th Frankfurt Jazz Festival in Germany in September...
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p53 is a 1996 live album by experimental music group p53. It was their debut album and was recorded at the 25th Frankfurt Jazz Festival in Germany on 16...
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cyclin-CDK complexes. The p53 tumor-suppressor protein plays a crucial role at the G1/S checkpoint and the G2/M checkpoint. Activated p53 proteins result in...
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gene. It consists of recombinant adenovirus engineered to code for p53 protein (rAd-p53) and is manufactured by Shenzhen SiBiono GeneTech. Gendicine was...
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The p53 upregulated modulator of apoptosis (PUMA) also known as Bcl-2-binding component 3 (BBC3), is a pro-apoptotic protein, member of the Bcl-2 protein...
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Oncovirus (section Inactivation of p53)
tumor proteins p53 and the retinoblastoma proteins (Rb). It is evolutionarily advantageous for viruses to inactivate p53 because p53 can trigger cell...
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P21 (section p53 dependent response)
primarily associated with inhibition of CDK2. p21 represents a major target of p53 activity and thus is associated with linking DNA damage to cell cycle arrest...
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The p53 p63 p73 family is a family of tumor suppressor genes. This gene family codes the proteins: p53 TP73L (also known as "p63") p73 They are sometimes...
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respectively. The mutation of the P53 gene is the most common gene mutation found in cancer cells. A study has shown that p53 mutations are common in tobacco-related...
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Tumor suppressor p53-binding protein 1 also known as p53-binding protein 1 or 53BP1 is a protein that in humans is encoded by the TP53BP1 gene. 53BP1...
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P53 regulation associated lncRNA is a protein that in humans is encoded by the PRAL gene. "Human PubMed Reference:". National Center for Biotechnology...
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ThinkPad P series (redirect from ThinkPad P53)
processors and Nvidia Quadro Pascal-based graphics. A redesign of the P52, the P53 features a 4K UHD OLED Touch display, Wi-Fi 6, Intel 9th Gen Coffee Lake...
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G1/S transition (section p53 as a regulator)
S phase. The G1/S transition is highly regulated by transcription factor p53 in order to halt the cell cycle when DNA is damaged. It is a "point of no...
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Protein acetylation (section p53)
and post-translational modification of proteins, for example, histones, p53, and tubulins. Among these proteins, chromatin proteins and metabolic enzymes...
42 KB (4,895 words) - 08:33, 15 January 2024
P53-responsive gene 1 is a protein that in humans is encoded by the PRG1 gene. "Human PubMed Reference:". National Center for Biotechnology Information...
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P53 road is a regional road (P-Highway) in Zakarpattia Oblast, Ukraine. It runs north-south and connects Malyi Bereznyi with a Slovakia-Ukraine border...
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Cyclin B (section Cyclin B and p53)
cyclin B and the tumor suppressor gene p53. In general levels of p53 and cyclin B are negatively correlated. When p53 build-up triggers cell cycle arrest...
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2-Imidazoline (section As p53 activators)
antagonists of MDM2. These compounds bind MDM2/X in the p53-binding pocket and activate the p53 pathway in cancer cells, leading to cell cycle arrest,...
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Apoptosis (section Dysregulation of p53)
induce transcription of the p53 gene, resulting in the increase of p53 protein level and enhancement of cancer cell-apoptosis. p53 prevents the cell from replicating...
91 KB (10,621 words) - 14:34, 6 December 2024
USP7 (section Regulation of the p53 tumor suppressor)
tumor suppressor protein, p53. Normally, p53 levels are kept low in part due to Mdm2-mediated ubiquitylation and degradation of p53. In response to oncogenic...
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analogs which inhibit the interaction between mdm2 and tumor suppressor p53, and which were discovered by screening a chemical library by Vassilev et...
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Heterogeneous ribonucleoprotein particle (section p53)
coordination with p53. hnRNP K is rapidly induced after DNA damage by ionizing radiation. It cooperates with p53 to induce the activation of p53 target genes...
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SV40 (section p53 damage and carcinogenicity)
SV40 is an abbreviation for simian vacuolating virus 40 or simian virus 40, a polyomavirus that is found in both monkeys and humans. Like other polyomaviruses...
19 KB (2,247 words) - 15:34, 14 December 2024