• Thumbnail for Patch clamp
    The patch clamp technique is a laboratory technique in electrophysiology used to study ionic currents in individual isolated living cells, tissue sections...
    30 KB (3,853 words) - 01:56, 5 June 2024
  • Thumbnail for Electrophysiology
    involves impaling a cell with a fine electrode; patch-clamp recording takes a different approach. A patch-clamp microelectrode is a micropipette with a relatively...
    39 KB (4,513 words) - 10:23, 25 August 2024
  • Automated patch clamping is beginning to replace manual patch clamping as a method to measure the electrical activity of individual cells. Different techniques...
    19 KB (2,412 words) - 03:08, 13 April 2024
  • Thumbnail for Voltage clamp
    fluid while clamping, which is possible using patch clamp techniques. Another disadvantage involves "space clamp" issues. Cole's voltage clamp used a long...
    26 KB (3,681 words) - 06:30, 11 January 2024
  • study the function of bacterial ion channels through a technique called patch clamp, which was originally designed for characterizing the behavior of neurons...
    13 KB (1,333 words) - 04:16, 22 June 2024
  • Look up clamp or clamps in Wiktionary, the free dictionary. Clamp may refer to: Brick clamp, an early method of baking bricks Clamp (tool), a device or...
    2 KB (326 words) - 17:56, 22 September 2022
  • Patch-sequencing (patch-seq) is a modification of patch-clamp technique that combines electrophysiological, transcriptomic and morphological characterization...
    43 KB (5,261 words) - 16:24, 6 December 2023
  • Thumbnail for Erwin Neher
    for liquid junction potentials in patch clamp experiments". Correction for liquid junction potentials in patch clamp experiments. Methods in Enzymology...
    10 KB (811 words) - 09:08, 13 September 2024
  • membrane potential. Neuroscientists measure it using a technique known as patch clamping that allows them to record ion currents passing through individual channels...
    9 KB (1,079 words) - 05:36, 13 October 2022
  • Thumbnail for Ion transporter
    transport chain is regulated by the presence of H+ ions (pH) in solution. A patch clamp is an electrophysiology technique used to study channels and transporters...
    17 KB (2,039 words) - 00:13, 6 August 2024
  • Thumbnail for Action potential
    patch clamp by Erwin Neher and Bert Sakmann. For this discovery, they were awarded the Nobel Prize in Physiology or Medicine in 1991. Patch-clamping verified...
    149 KB (16,431 words) - 05:24, 30 July 2024
  • Thumbnail for Dendritic spike
    tool for studying dendritic spikes due to its high level of precision. Patch clamp recording is used to measure electrical activity in neurons. The technique...
    22 KB (2,986 words) - 13:19, 29 December 2023
  • Thumbnail for Inchworm motor
    connecting the motor to a feedback system. The inchworm motor can be used in patch clamping of biological cells. This technique is most often performed with an...
    4 KB (502 words) - 03:30, 11 July 2021
  • ethanol. Voltage clamp recordings have been done on the aplysia neuron. VGCCs were isolated and calcium current was recorded using patch clamp technique having...
    29 KB (3,270 words) - 15:49, 13 July 2024
  • (intracellular recording of the properties of single neurons), such as patch clamp, voltage clamp, extracellular single-unit recording and recording of local field...
    16 KB (1,839 words) - 13:22, 8 August 2024
  • Thumbnail for Ion channel
    electrophysiology, and pharmacology, while using techniques including voltage clamp, patch clamp, immunohistochemistry, X-ray crystallography, fluoroscopy, and RT-PCR...
    44 KB (5,175 words) - 04:08, 10 September 2024
  • Retrieved 2022-03-03. Molleman, Areles (2003). "Patch Clamping: An Introductory Guide to Patch Clamp Electrophysiology". Wiley & Sons. ISBN 978-0-471-48685-5...
    18 KB (1,796 words) - 04:15, 9 May 2024
  • proportional to magnitude of the disturbance in the electric field. Patch-Clamp Electrophysiology was developed by Neher and Sakmann in 1976. This technique...
    10 KB (1,321 words) - 07:09, 13 August 2024
  • Thumbnail for Bert Sakmann
    function of single ion channels in cells," and the invention of the patch clamp. Bert Sakmann was Professor at Heidelberg University and is an Emeritus...
    8 KB (642 words) - 09:12, 13 September 2024
  • Thumbnail for Single-molecule experiment
    molecules have been developed. The first single-molecule experiments were patch clamp experiments performed in the 1970s, but these were limited to studying...
    18 KB (2,203 words) - 04:23, 12 February 2024
  • single cells due to their low spatial resolution compared to patch clamp and dynamic clamp systems. The complexity of signals an MEA electrode could effectively...
    39 KB (4,674 words) - 20:17, 3 September 2024
  • Thumbnail for Vesicle (biology and chemistry)
    more easily investigated with patch clamp techniques, vesicles can also be isolated from objects for which a patch clamp is not applicable. Artificial...
    36 KB (3,649 words) - 05:36, 29 June 2024
  • Thumbnail for Stimulus (physiology)
    potential across the membrane can be obtained by microelectrode recording. Patch clamp techniques allow for the manipulation of the intracellular or extracellular...
    31 KB (3,971 words) - 21:25, 25 May 2024
  • Thumbnail for Saltatory conduction
    electric signals Neurotransmission – Impulse transmission between neurons Patch clamp – Laboratory technique in electrophysiology Quantitative models of the...
    7 KB (733 words) - 13:43, 29 July 2024
  • essential to creation of the glass pipettes used for the patch clamp technique of voltage clamping. Various machines and torches/gas burners are used in...
    2 KB (275 words) - 07:57, 22 June 2023
  • Thumbnail for Orphenadrine
    uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist: binding and patch clamp studies". Journal of Neural Transmission. General Section. 102 (3): 237–46...
    18 KB (1,550 words) - 11:17, 22 March 2024
  • Thumbnail for Lipid bilayer
    Biacore Inc. Retrieved Feb 12, 2009. Nanion Technologies. Automated Patch Clamp Archived 31 March 2010 at the Wayback Machine. Retrieved Feb 28, 2010...
    81 KB (9,779 words) - 13:40, 28 May 2024
  • Thumbnail for Neuronal noise
    contributed much to discovering many of the new sources of ion channel noise. Patch clamp technique was crucial to determine shot noise because the use of intercellular...
    18 KB (2,370 words) - 00:01, 27 April 2024
  • simultaneously from both sides of the die was produced by Yale e-Lab) patch-clamp amplifiers energy harvesting devices three-dimensional (3D) integration...
    11 KB (1,165 words) - 18:03, 13 September 2024
  • Thumbnail for Nystatin
    Nystatin is also used as a tool by scientists performing "perforated" patch-clamp electrophysiological recordings of cells. When loaded in the recording...
    29 KB (2,600 words) - 08:44, 6 August 2024