iPSCs are typically derived by introducing products of specific sets of pluripotency-associated genes, or "reprogramming factors", into a given cell type...

totipotency to designate a cell with the most differentiation potential, pluripotency, multipotency, oligopotency, and finally unipotency. Totipotency (Latin:...

share many similar properties, such as pluripotency and differentiation potential, the expression of pluripotency genes, epigenetic patterns, embryoid body...

The pluripotency of biological compounds describes the ability of certain substances to produce several distinct biological responses. Pluripotent is also...

embryonic stem cells and are necessary for the maintenance of their pluripotency. It is thought that they achieve this through alterations in chromatin...

ability to maintain pluripotency throughout embryonic development. Recently, it has been noted that OCT-4 not only maintains pluripotency in embryonic cells...

Stimulus-triggered acquisition of pluripotency (STAP) was a proposed method of generating pluripotent stem cells by subjecting ordinary cells to certain...

Physical Review, also retracted papers by Schön. In 2024, a paper titled "Pluripotency of mesenchymal stem cells derived from adult marrow," published in 2002...

cells that in subsequently differentiate into the desired cell types. Pluripotency distinguishes embryonic stem cells from adult stem cells, which are multipotent...

Oct4: Oct4 is expressed in the ICM and participate in maintaining its pluripotency, a role that has been recapitulated in ICM derived mouse embryonic stem...

more restricted in the differentiation potential and eventually lose pluripotency. In 1962, John B. Gurdon demonstrated that the nucleus from a differentiated...

turn into neurons by virtue of their stem cell-like characteristic of pluripotency. Like all animal cells, the cell body of every neuron is enclosed by...

coding potential, have been found associated with regulation of stem cell pluripotency and cell division. The third major group of regulatory RNAs is called...

has indicated that it was possible to replicate cells and reestablish pluripotency, or "the potential of an embryonic cell to grow into any one of the numerous...

response and inflammation Neural and muscular degeneration Maintenance of pluripotency Morphogenesis of neural networks Modulation of cell surface receptors...

(February 2014). "Protein post-translational modifications and regulation of pluripotency in human stem cells". Cell Research. 24 (2): 143–160. doi:10.1038/cr...

transcription factor that is essential for maintaining self-renewal, or pluripotency, of undifferentiated embryonic stem cells. Sox2 has a critical role in...

and remarkably easy way to generate stimulus-triggered acquisition of pluripotency (STAP) cells that could be grown into tissue for use anywhere in the...

of pluripotency maintenance genes. The expression of transcription factors such as the SON factor and epigenetic modifiers regulate the pluripotency of...

as a major determinant for transition between totipotency and naïve pluripotency states. From 2013, Hanna worked as the Robertson Stem Cell Investigator...

expression of pluripotency. The main indicator that the initiation phase has completed is that the first genes associated with pluripotency are expressed...

Zernicka-Goetz, Magdalena (2007). "Histone arginine methylation regulates pluripotency in the early mouse embryo". Nature. 445 (7124): 214–218. Bibcode:2007Natur...

Soncin, F.; Ward, M.C. (2011). "The Function of E-Cadherin in Stem Cell Pluripotency and Self-Renewal". Genes. 2 (1): 229–259. doi:10.3390/genes2010229. PMC 3924836...

Lygerou Z, Taraviras S (June 2014). "Licensing of DNA replication, cancer, pluripotency and differentiation: an interlinked world?". Seminars in Cell & Developmental...

PMC 3471363. PMID 23021216. Gearhart J, Pashos EE, Prasad MK (October 2007). "Pluripotency redux--advances in stem-cell research". The New England Journal of Medicine...

"Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28". Nature Structural & Molecular Biology. 19 (1): 84–89....

until nothing remains, at which time the cells cease to divide. Induced pluripotency can lengthen telomere cap such that the cells divide indefinitely. Cell...

FOXO4 (widely expressed), FOXO6 (liver, skeletal muscle, brain) FOXP1 (pluripotency then brain, heart and lung), FOXP2 (widely expressed? brain; language)...

these TADs of interest, and found significant participation of major pluripotency factors such as OCT4, NANOG, and SOX2 in the interaction network during...

R, Radzisheuskaya A, et al. (March 2014). "Citrullination regulates pluripotency and histone H1 binding to chromatin". Nature. 507 (7490): 104–8. Bibcode:2014Natur...