Poly(A)-binding protein (PAB or PABP) is an RNA-binding protein which triggers the binding of eukaryotic initiation factor 4 complex (eIF4G) directly to...
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Polyadenylation (redirect from Poly-A tail)
spliceosome, a complex that removes introns from RNAs. The poly(A) tail acts as the binding site for poly(A)-binding protein. Poly(A)-binding protein promotes...
57 KB (7,094 words) - 23:56, 6 August 2024
Poly(A) binding protein interacting protein 2B is a protein that in humans is encoded by the PAIP2B gene. Most mRNAs, except for histones, contain a 3-prime...
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Three prime untranslated region (section Poly(A) tail)
several hundred adenine residues called the poly(A) tail to the end of the mRNA transcript. Poly(A) binding protein (PABP) binds to this tail, contributing...
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Single-strand binding protein Telomere-binding protein RNA-binding protein Poly(A)-binding protein Nuclear cap-binding protein complex CREB-binding protein Calcium-binding...
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PABPC1 (redirect from Poly(a)-binding proteins)
the role of that protein and its function with RNA. The poly(A)-binding protein (PAB or PABP), which is found complexed to the 3' poly(A) tail of eukaryotic...
14 KB (1,663 words) - 02:04, 8 April 2024
PCBP1 (redirect from Poly(rC)-binding protein)
Poly(rC)-binding protein 1 is a protein that in humans is encoded by the PCBP1 gene. This intronless gene is thought to have been generated by retrotransposition...
8 KB (1,155 words) - 11:40, 8 April 2024
gene. PABN1 is a member of a larger family of poly(A)-binding proteins in the human genome. This gene encodes an abundant nuclear protein that binds with...
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Messenger RNA (category Protein biosynthesis)
eIF-4E and eIF-4G, and poly(A)-binding protein. eIF-4E and eIF-4G block the decapping enzyme (DCP2), and poly(A)-binding protein blocks the exosome complex...
49 KB (5,922 words) - 14:24, 18 August 2024
poly(A)-binding protein, recruits and stimulates the activity of poly(A) polymerase. Poly(A) polymerase is inactive on its own and requires the binding of these...
39 KB (4,540 words) - 18:39, 20 July 2024
poly-A binding protein (PABP) appears to play a role in this stability. It has been demonstrated in other studies that the presence of this protein near...
29 KB (3,394 words) - 21:28, 16 March 2024
PMC 1524897. PMID 16804161. "Entrez Gene: PAIP2 poly(A) binding protein interacting protein 2". Khaleghpour K, Kahvejian A, De Crescenzo G, Roy G, Svitkin YV, Imataka...
6 KB (789 words) - 09:51, 17 October 2022
Polyadenylate-binding protein 3 is a protein that in humans is encoded by the PABPC3 gene. PABPC3 is a member of a larger family of poly(A)-binding proteins in the...
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Polyadenylate-binding protein 4 (PABPC4) is a protein that in humans is encoded by the PABPC4 gene. Poly(A)-binding proteins (PABPs) bind to the poly(A) tail...
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half-life of mRNA. In addition, a long poly(A) tail can increase translation. Poly(A)-binding protein (PABP) binds to a long poly(A) tail and mediates the interaction...
27 KB (3,383 words) - 23:03, 16 March 2024
As the poly(A) tail is synthesized, it binds multiple copies of poly(A)-binding protein, which protects the 3'end from ribonuclease digestion by enzymes...
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PAIP1 (category Protein stubs)
Polyadenylate-binding protein-interacting protein 1 is a protein that in humans is encoded by the PAIP1 gene. The protein encoded by this gene interacts with poly(A)-binding...
5 KB (601 words) - 00:08, 3 December 2023
A ribosome binding site, or ribosomal binding site (RBS), is a sequence of nucleotides upstream of the start codon of an mRNA transcript that is responsible...
12 KB (1,336 words) - 13:08, 20 June 2024
PABPC4L (category Human proteins)
Poly(A) binding protein, cytoplasmic 4-like is a protein that in humans is encoded by the PABPC4L gene. GRCh38: Ensembl release 89: ENSG00000254535 – Ensembl...
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ADP-ribosylation (redirect from Poly(ADP-ribosyl)ation)
to the synthesis of poly(ADP-ribose). The PBZ domain is present in many proteins involved in DNA repair and allows for the binding of the PARP and thus...
29 KB (3,535 words) - 13:23, 4 January 2024
PABPC5 (category Proteins)
Poly(A) binding protein cytoplasmic 5 is a protein that in humans is encoded by the PABPC5 gene. This gene encodes a poly(A)-binding protein that binds...
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Poly(a) binding protein interacting protein 2b PARK3 encoding protein Parkinson disease 3 (autosomal dominant, Lewy body) PCBP1-AS1: encoding protein...
40 KB (2,534 words) - 05:56, 28 July 2024
Example metal binding proteins Metal-binding proteins are proteins or protein domains that chelate a metal ion. Binding of metal ions via chelation is...
5 KB (500 words) - 02:41, 22 June 2024
40S ribosomal subunits, translation initiation factors, poly(A)+ mRNAs and RNA-binding proteins (RBPs). While they are membraneless organelles, stress...
183 KB (12,458 words) - 20:40, 1 July 2024
Poly(rC)-binding protein 2 is a protein that in humans is encoded by the PCBP2 gene. The protein encoded by this gene appears to be multifunctional. It...
10 KB (1,285 words) - 04:09, 30 April 2024
Housekeeping gene (section RNA binding protein)
heterogeneous nuclear ribonucleoprotein K (HNRPK), transcript PABPN1 poly(A) binding protein, nuclear 1 SRSF3 splicing factor, arginine/serine-rich EIF1 aka...
48 KB (4,612 words) - 23:41, 12 December 2023
of a human cytoplasmic poly(A) nuclease complex stimulated by poly(A)-binding protein". J. Biol. Chem. 279 (2): 1383–91. doi:10.1074/jbc.M309125200....
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gov/gene/8106 Archived 2021-05-07 at the Wayback Machine "PABPN1 poly(A) binding protein, nuclear 1 [ Homo sapiens (human) ]"]11 OCT 2014. "Oculopharyngeal...
20 KB (1,189 words) - 14:53, 24 August 2024