springs and hydrothermal vents, and Taq polymerase was identified as an enzyme able to withstand the protein-denaturing conditions (high temperature)...

The polymerase chain reaction (PCR) is a method widely used to make millions to billions of copies of a specific DNA sample rapidly, allowing scientists...

In molecular biology, RNA polymerase (abbreviated RNAP or RNApol), or more specifically DNA-directed/dependent RNA polymerase (DdRP), is an enzyme that...

bind the RNA polymerase responsible for transcription, either directly or through other mediator proteins; this locates the polymerase at the promoter...

eukaryotic DNA polymerases and their accessory proteins". The Journal of Biological Chemistry. 266 (3): 1950–60. doi:10.1016/S0021-9258(18)52385-1. PMID 1671045...

(October 1996). "Influenza virus polymerase basic protein 1 interacts with influenza virus polymerase basic protein 2 at multiple sites". J Virol. 70...

into structural proteins by host cell machinery. During replication of the negative-sense viral genome, RNA-dependent RNA polymerase synthesizes a positive-sense...

pairing can potentially result in dysfunctional proteins and could lead to cancer. Many DNA polymerases contain an exonuclease domain, which acts in detecting...

in the PR reading frame. The N protein is an antiterminator, and functions by engaging the transcribing RNA polymerase at specific sites of the nascently...

Protein biosynthesis (or protein synthesis) is a core biological process, occurring inside cells, balancing the loss of cellular proteins (via degradation...

of proteins are associated with the replication fork to help in the initiation and continuation of DNA synthesis. Most prominently, DNA polymerase synthesizes...

Protein phosphatase 1 (PP1) belongs to a certain class of phosphatases known as protein serine/threonine phosphatases. This type of phosphatase includes...

recombinant protein under the control of the T7 promoter is 8x faster than protein expression under the control of E. coli RNA polymerase. Basal levels...

TFIIB recruits RNA polymerase II and TFIIF to the promoter. TFIIE joins the growing complex and recruits TFIIH which has protein kinase activity (phosphorylates...

from DNA to messenger RNA. GTFs, RNA polymerase, and the mediator (a multi-protein complex) constitute the basic transcriptional apparatus that first...

terminators require a large protein called a Rho factor which exhibits RNA helicase activity to disrupt the mRNA-DNA-RNA polymerase transcriptional complex...

secure initial binding site for RNA polymerase and for proteins called transcription factors that recruit RNA polymerase. These transcription factors have...

heat-resistant enzyme Taq DNA polymerase, one of the most important enzymes in molecular biology because of its use in the polymerase chain reaction (PCR) DNA...

Basic helix-loop-helix ARNT-like protein 1 or aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL), or brain and muscle ARNT-like 1 is...

supported the sequencing of complex proteins. In 1999, Roger Kornberg sequenced the highly complex structure of RNA polymerase using high intensity X-rays from...

protein to bind to DNA during the formation of the transcription preinitiation complex of RNA polymerase II (RNA Pol II). As one of the few proteins in...

Retrieved 2018-05-07. "PB2 - Polymerase basic protein 2 - Influenza A virus (strain A/Wilson-Smith/1933 H1N1) - PB2 gene & protein". www.uniprot.org. Retrieved...

polymerase requires a host factor, E. coli thioredoxin, in order to carry out its function. This helps stabilize the binding of the necessary protein...

H and N proteins in the viral envelope; for example, "H1N1" designates an IAV subtype that has a type-1 hemagglutinin (H) protein and a type-1 neuraminidase...

rRNA genes are transcribed as a single unit within the nucleolus by RNA polymerase I. In order for this transcription to occur, several pol I-associated...

tertiary, and/or quaternary structures of proteins or nucleic acids resulting in a loss of bioactivity. Note 1: Modified from the definition given in ref...

RNA polymerase and other proteins for the successful initiation of transcription directly upstream of the gene. Operators recognize repressor proteins that...

factor 2 (FGF-2), also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by the FGF2 gene. It binds...

protein factors, RNA polymerase transcription factor II B, CCAAT binding factors, or CCAAT enhancer binding proteins were found. The TMEM251 protein is...

of RNA Polymerase. CAP activates transcription through protein-protein interactions with the α-subunit of RNA Polymerase. This protein-protein interaction...