Subtilisin is a protease (a protein-digesting enzyme) initially obtained from Bacillus subtilis. Subtilisins belong to subtilases, a group of serine proteases...

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1. It is the 9th member of the proprotein...

categories based on their structure: chymotrypsin-like (trypsin-like) or subtilisin-like. The MEROPS protease classification system counts 16 superfamilies...

(and should not be pronounced as such), but a serine protease of the subtilisin family (99.5% identical with aprE). Rather, it is named for the fact that...

DNA polymerase I from E. coli is enzymatically cleaved by the protease subtilisin. First reported in 1970, it retains the 5' → 3' polymerase activity and...

family S8, furin is a subtilisin-like peptidase. The protein encoded by this gene is an enzyme that belongs to the subtilisin-like proprotein convertase...

bacterial dysentery; its efficacy (probably attributable to the antibiotic subtilisin from Bacillus subtilis) was anecdotally confirmed by German soldiers in...

In molecular biology the protein SSI is a Subtilisin inhibitor-like which stands for Streptomyces subtilisin inhibitor. This is a protease inhibitor. These...

substrate). It is related to the bacterial enzyme known as subtilisin. There are nine subtilisin homologs in mammals; in addition to proprotein convertase...

preventing the enzyme from sucking in the chain past the first residue. 1969 – Subtilisin (PDB file 1sbt ) was a second type of serine protease with a near-identical...

Ottesen M, Richards FM (February 1955). "Degradation of ribonuclease by subtilisin". Biochimica et Biophysica Acta. 16 (2): 297–299. doi:10.1016/0006-3002(55)90224-9...

a fully human monoclonal antibody that inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9). PCSK9 is a protein that targets LDL receptors for...

Subtilases are a family of subtilisin-like serine proteases. They appear to have independently and convergently evolved an Asp/Ser/His catalytic triad...

licheniformis one of the most important bacteria in industrial enzyme production. Subtilisin Carlsberg (P00780) secreted by B. licheniformis is used as a detergent...

sp, subtilisin-like pernisine from Aeropyrum pernix, alkaline protease from Nocardiopsis sp, nattokinase from B. subtilis, engineered subtilisins from...

production of alpha amylase used in starch hydrolysis and the protease subtilisin used in detergents. B. subtilis is a valuable model for bacterial research...

site serines and are part of inhibitors for porcine pancreatic lipase, subtilisin and the protease Kex2. Furthermore, boronic acid derivatives constitute...

organisation of acid-base-nucleophile in different protease superfamilies. Shown are the triads of subtilisin, prolyl oligopeptidase, TEV protease, and papain....

Searching for "Subtilisin" returns the protein, "Subtilisin from Bacillus subtilis, carlsberg", with the following lineage. Subtilisin from Bacillus subtilis...

specifically, inhibiting translation of the protein termed proprotein convertase subtilisin/kexin type 9 (PCSK9). Small interfering RNA molecules (siRNAs) are designed...

for its broad specificity. This enzyme belongs to Peptidase family S8 (subtilisin). The molecular weight of Proteinase K is 28,900 daltons (28.9 kDa). Activated...

oligonucleopeptides (such as Pelacarsen and Olpasiran), and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors. The American Academy of Pediatrics now...

Digestive aid Urokinase Pharmaceutical Anticoagulant β-Lactamase Pharmaceutical Penicillin allergy treatment Subtilisin Consumer Goods Laundry detergent...

2019. Bogacheva AM, Rudenskaya GN, Preusser A, et al. (1999). "A new subtilisin-like proteinase from roots of the dandelion Taraxacum officinale Webb...

Proprotein convertase subtilisin/kexin type 1 inhibitor is a protein by the name of proSAAS that in humans is encoded by the PCSK1N gene. This protein...

antibody Type Whole antibody Source Human Target Proprotein convertase subtilisin/kexin type 9 (PCSK9) Clinical data Trade names Praluent AHFS/Drugs.com...

organisation of acid-base-nucleophile in different protease superfamilies. Shown are the triads of subtilisin, prolyl oligopeptidase, TEV protease, and papain....

similar strategy of employing an inactive zymogen or prezymogen is used. Subtilisin, which is produced by Bacillus subtilis, is produced as preprosubtilisin...

Phytaspase is a member of the plant subtilisin-like protease family, and is commonly distinguished from the other members by its unusual and extremely...

Simultaneously, the structures of the evolutionarily unrelated papain and subtilisin proteases were found to contain analogous triads. The 'charge-relay' mechanism...