encoded by the TRPV5 gene. The TRPV5 gene is a member of the transient receptor family and the TRPV subfamily. The calcium-selective channel, TRPV5, encoded...
8 KB (973 words) - 09:50, 22 December 2023
thiazide-sensitive Na-Cl cotransporter and are permeable to Ca, via the TRPV5 channel. On the basolateral surface (peritubular capillary side) there is...
5 KB (482 words) - 10:33, 21 August 2024
TRPV5. About 95% to 98% of Ca2+ filtered from the blood by the kidney is normally reabsorbed by the kidney's renal tubule, which is mediated by TRPV5...
38 KB (4,036 words) - 18:01, 9 November 2024
high Ca2+-selectivity of TRPV5 and TRPV6 makes these channels distinct from the other four TRPV channels (TRPV1-TRPV4). TRPV5 and TRPV6 are involved in...
94 KB (10,475 words) - 03:37, 24 March 2024
potent and selective inhibitor for the TRPV5 calcium channel, with an IC50 of 177 nM and high selectivity for TRPV5 over TRPV6 and the other subtypes of...
2 KB (99 words) - 04:14, 25 September 2024
the tubules to enter epithelial cells via apical Ca2+-selective channels (TRPV5). In other words, less Ca2+ in the cell increases the driving force for...
23 KB (2,442 words) - 22:05, 21 October 2024
"Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1". Proceedings of the National Academy...
16 KB (1,840 words) - 07:12, 2 November 2024
(CatSper1, TASK, RyR1, RyR2, RyR3, TRPM6, TRPM8, TRPV1, TRPV2, TRPV3, TRPV4, TRPV5, TRPV6, TRPA1, mCa1, mCa2, CALHM1) TRPP3, a plant ion channel, Ca2+-ATPase...
6 KB (487 words) - 19:02, 22 September 2023
cnidarians, nematodes, annelids, molluscs, and arthropods (possibly excluding arachnids) Inactive TRPV1 Specific to vertebrates TRPV2 TRPV3 TRPV4 TRPV5 TRPV6...
49 KB (5,517 words) - 15:04, 1 October 2024
through the interaction with p11. Some of these proteins include Nav1.8, TRPV5, TRPV6, TASK-1, and ASIC1a. Nav1.8 is a tetrodotoxin-resistant sodium channel...
39 KB (4,728 words) - 15:30, 23 December 2023
and internal organs; human sperm 6:1 aquaporin 5, calmodulin, pacsin 3 2 TRPV5 calcium-selective TRP channel intestine, kidney, placenta 100:1 TRPV6 annexin...
13 KB (1,271 words) - 23:41, 6 March 2024
G, Sauvé R, Parent L (February 2004). "Outer pore topology of the ECaC-TRPV5 channel by cysteine scan mutagenesis". The Journal of Biological Chemistry...
13 KB (1,621 words) - 02:21, 29 November 2023
associated with IH were selected for genetic screening, including VDR, TRPV5, CasR, and NPT2a. IH is also associated with many monogenic disorders, whether...
28 KB (3,178 words) - 04:55, 1 September 2024
the conductance of most TRP channels either positively or negatively. For TRPV5, binding of PIP2 to a site in the transmembrane domain caused a conformational...
16 KB (1,928 words) - 01:58, 26 June 2024
"Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1". Proceedings of the National Academy...
14 KB (1,756 words) - 10:15, 6 January 2024
TRP7; TRPA1; TRPC3; TRPC4; TRPC5; TRPC6; TRPC7; TRPV1; TRPV2; TRPV3; TRPV4; TRPV5; TRPV6; UACA; USH1G; ZDHHC13; ZDHHC17; DARPin (designed ankyrin repeat protein)...
14 KB (1,393 words) - 19:22, 1 December 2023
outer medullary K+ channel KCNJ1 (ROMK1) Renal epithelial Ca2+ channel TRPV5 Ubiquitous Cl− channel CLCN2 (ClC2) Cardiac voltage-gated Na+ channel SCN5A...
35 KB (4,214 words) - 16:52, 11 August 2024
Peng JB (2008). "WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway". Am. J. Physiol. Renal Physiol...
7 KB (929 words) - 05:27, 3 June 2024
TRPM2; TRPM3; TRPM4; TRPM5; TRPM6; TRPM7; TRPM8 TRPV1; TRPV2; TRPV3; TRPV4; TRPV5; TRPV6 MCOLN1; MCOLN2; MCOLN3; TRPA1 PKD1L3; CACNA1A; CACNA1B; CACNA1C;...
19 KB (1,692 words) - 03:53, 29 November 2023
Q9Y5S1 17482 TRPV3 HGNC:18084 Q8NET8 17483 TRPV4 HGNC:18083 Q9HBA0 17484 TRPV5 HGNC:3145 Q9NQA5 17485 TRPV6 HGNC:14006 Q9H1D0 17486 TRRAP HGNC:12347 Q9Y4A5...
242 KB (17 words) - 18:43, 6 October 2024
TRPM5 TRPM6 TRPM7 TRPM8 TRPML TRPN TRPP TRPP3 TRPV TRPV1 TRPV2 TRPV3 TRPV4 TRPV5 TRPV6 Talin protein Tandem pore domain potassium channel Tatyana Sapunova...
15 KB (1,545 words) - 18:32, 17 August 2024
the total and cell surface expression of these channels. WNK4 enhances TRPV5 by increasing its forward trafficking to the plasma membrane in a kinase-dependent...
31 KB (3,448 words) - 22:12, 9 October 2024