• Thumbnail for TRPV5
    encoded by the TRPV5 gene. The TRPV5 gene is a member of the transient receptor family and the TRPV subfamily. The calcium-selective channel, TRPV5, encoded...
    8 KB (973 words) - 09:50, 22 December 2023
  • Thumbnail for Distal convoluted tubule
    thiazide-sensitive Na-Cl cotransporter and are permeable to Ca, via the TRPV5 channel. On the basolateral surface (peritubular capillary side) there is...
    5 KB (482 words) - 10:33, 21 August 2024
  • Thumbnail for Klotho (biology)
    TRPV5. About 95% to 98% of Ca2+ filtered from the blood by the kidney is normally reabsorbed by the kidney's renal tubule, which is mediated by TRPV5...
    38 KB (4,036 words) - 18:01, 9 November 2024
  • Thumbnail for TRPV6
    high Ca2+-selectivity of TRPV5 and TRPV6 makes these channels distinct from the other four TRPV channels (TRPV1-TRPV4). TRPV5 and TRPV6 are involved in...
    94 KB (10,475 words) - 03:37, 24 March 2024
  • Thumbnail for ZINC17988990
    potent and selective inhibitor for the TRPV5 calcium channel, with an IC50 of 177 nM and high selectivity for TRPV5 over TRPV6 and the other subtypes of...
    2 KB (99 words) - 04:14, 25 September 2024
  • Thumbnail for Thiazide
    the tubules to enter epithelial cells via apical Ca2+-selective channels (TRPV5). In other words, less Ca2+ in the cell increases the driving force for...
    23 KB (2,442 words) - 22:05, 21 October 2024
  • Thumbnail for Fibroblast growth factor 23
    "Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1". Proceedings of the National Academy...
    16 KB (1,840 words) - 07:12, 2 November 2024
  • Thumbnail for Ruthenium red
    (CatSper1, TASK, RyR1, RyR2, RyR3, TRPM6, TRPM8, TRPV1, TRPV2, TRPV3, TRPV4, TRPV5, TRPV6, TRPA1, mCa1, mCa2, CALHM1) TRPP3, a plant ion channel, Ca2+-ATPase...
    6 KB (487 words) - 19:02, 22 September 2023
  • cnidarians, nematodes, annelids, molluscs, and arthropods (possibly excluding arachnids) Inactive TRPV1 Specific to vertebrates TRPV2 TRPV3 TRPV4 TRPV5 TRPV6...
    49 KB (5,517 words) - 15:04, 1 October 2024
  • Thumbnail for S100A10
    through the interaction with p11. Some of these proteins include Nav1.8, TRPV5, TRPV6, TASK-1, and ASIC1a. Nav1.8 is a tetrodotoxin-resistant sodium channel...
    39 KB (4,728 words) - 15:30, 23 December 2023
  • Thumbnail for TRPV
    and internal organs; human sperm 6:1 aquaporin 5, calmodulin, pacsin 3 2 TRPV5 calcium-selective TRP channel intestine, kidney, placenta 100:1 TRPV6 annexin...
    13 KB (1,271 words) - 23:41, 6 March 2024
  • G, Sauvé R, Parent L (February 2004). "Outer pore topology of the ECaC-TRPV5 channel by cysteine scan mutagenesis". The Journal of Biological Chemistry...
    13 KB (1,621 words) - 02:21, 29 November 2023
  • Thumbnail for Idiopathic hypercalcinuria
    associated with IH were selected for genetic screening, including VDR, TRPV5, CasR, and NPT2a. IH is also associated with many monogenic disorders, whether...
    28 KB (3,178 words) - 04:55, 1 September 2024
  • Thumbnail for Lipid-gated ion channels
    the conductance of most TRP channels either positively or negatively. For TRPV5, binding of PIP2 to a site in the transmembrane domain caused a conformational...
    16 KB (1,928 words) - 01:58, 26 June 2024
  • Thumbnail for ROMK
    "Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1". Proceedings of the National Academy...
    14 KB (1,756 words) - 10:15, 6 January 2024
  • Thumbnail for Ankyrin repeat
    TRP7; TRPA1; TRPC3; TRPC4; TRPC5; TRPC6; TRPC7; TRPV1; TRPV2; TRPV3; TRPV4; TRPV5; TRPV6; UACA; USH1G; ZDHHC13; ZDHHC17; DARPin (designed ankyrin repeat protein)...
    14 KB (1,393 words) - 19:22, 1 December 2023
  • Thumbnail for SGK1
    outer medullary K+ channel KCNJ1 (ROMK1) Renal epithelial Ca2+ channel TRPV5 Ubiquitous Cl− channel CLCN2 (ClC2) Cardiac voltage-gated Na+ channel SCN5A...
    35 KB (4,214 words) - 16:52, 11 August 2024
  • Thumbnail for WNK3
    Peng JB (2008). "WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway". Am. J. Physiol. Renal Physiol...
    7 KB (929 words) - 05:27, 3 June 2024
  • Thumbnail for Cation channel superfamily
    TRPM2; TRPM3; TRPM4; TRPM5; TRPM6; TRPM7; TRPM8 TRPV1; TRPV2; TRPV3; TRPV4; TRPV5; TRPV6 MCOLN1; MCOLN2; MCOLN3; TRPA1 PKD1L3; CACNA1A; CACNA1B; CACNA1C;...
    19 KB (1,692 words) - 03:53, 29 November 2023
  • Q9Y5S1 17482 TRPV3 HGNC:18084 Q8NET8 17483 TRPV4 HGNC:18083 Q9HBA0 17484 TRPV5 HGNC:3145 Q9NQA5 17485 TRPV6 HGNC:14006 Q9H1D0 17486 TRRAP HGNC:12347 Q9Y4A5...
    242 KB (17 words) - 18:43, 6 October 2024
  • TRPM5 TRPM6 TRPM7 TRPM8 TRPML TRPN TRPP TRPP3 TRPV TRPV1 TRPV2 TRPV3 TRPV4 TRPV5 TRPV6 Talin protein Tandem pore domain potassium channel Tatyana Sapunova...
    15 KB (1,545 words) - 18:32, 17 August 2024
  • Thumbnail for WNK4
    the total and cell surface expression of these channels. WNK4 enhances TRPV5 by increasing its forward trafficking to the plasma membrane in a kinase-dependent...
    31 KB (3,448 words) - 22:12, 9 October 2024