In molecular biology, the HMG-box (high mobility group box) is a protein domain which is involved in DNA binding. The domain is composed of approximately...
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High-mobility group (redirect from HMG protein)
containing any of these embedded in their sequence are known as HMG motif proteins. HMG-box proteins are found in a variety of eukaryotic organisms. They...
5 KB (545 words) - 02:57, 18 June 2024
SOX genes (SRY-related HMG-box genes) encode a family of transcription factors that bind to the minor groove in DNA, and belong to a super-family of genes...
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HMGB1 (redirect from High-mobility group box 1)
group box 1 protein, also known as high-mobility group protein 1 (HMG-1) and amphoterin, is a protein that in humans is encoded by the HMGB1 gene. HMG-1 belongs...
26 KB (3,169 words) - 07:01, 25 July 2024
sequence also changes; while the core of the gene, the high-mobility group (HMG) box, is conserved between species, other regions of the gene are not. SRY is...
39 KB (4,855 words) - 12:42, 9 August 2024
DNA-binding domain (section HMG-box)
another helix. The larger helix typically contains the DNA-binding regions. HMG-box domains are found in high mobility group proteins which are involved in...
19 KB (2,157 words) - 07:17, 19 July 2024
HMGXB4 (redirect from Hmg-box containing 4)
HMG-box containing 4 is a protein that in humans is encoded by the HMGXB4 gene. High mobility group (HMG) proteins are nonhistone chromosomal proteins...
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mobility group protein 1). Some high mobility group (HMG) box proteins (e.g., LEF1) contain a single HMG box motif and bind DNA in a sequence-specific manner...
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tongue groove This condition is caused by mutations in the SRY-related HMG-box (SOX5) gene. This gene encodes a protein in the family of transcription...
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heterozygous SOX9 mutations can cause CMD: amino acid substitutions in the HMG-box, truncations or frameshifts that alter the C-terminal end, mutations at...
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Medicine. "Entrez Gene: TCF7 transcription factor 7 (T-cell specific, HMG-box)". van de Wetering M, Oosterwegel M, Holstege F, et al. (1992). "The human...
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WD repeat and HMG-box DNA binding protein 1 is a protein in humans that is encoded by the WDHD1 gene. The protein encoded by this gene contains multiple...
1 KB (160 words) - 06:53, 29 June 2024
HMG-box containing 3 is a protein that in humans is encoded by the HMGXB3 gene. This gene is one of the non-canonical high mobility group (HMG) genes....
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chromosome 11 [citation needed]. UBTF contains six high mobility group boxes (HMG-boxes) that allow it to bind to DNA. UBTF also contains a hyperacidic carboxy-terminal...
19 KB (2,154 words) - 04:04, 28 November 2023
simulation software DNA-binding domain Helix-loop-helix Helix-turn-helix HMG-box Leucine zipper Lexitropsin (a semi-synthetic DNA-binding ligand) Deoxyribonucleoprotein...
22 KB (2,629 words) - 04:17, 19 August 2024
encoded by the SOX3 gene. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic...
11 KB (1,396 words) - 05:30, 5 August 2024
regions devoid of histones become very fragile after transcription; HMO1, an HMG-box protein, helps in stabilizing nucleosomes-free chromatin. A variety of...
53 KB (5,924 words) - 18:46, 4 August 2024
determining region Y)-box 30 is a protein that in humans is encoded by the SOX30 gene. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription...
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factors 4.6 Class: TATA binding proteins 4.6.1 Family: TBP 4.7 Class: HMG-box 4.7.1 Family: SOX genes, SRY 4.7.2 Family: TCF-1 (TCF1) 4.7.3 Family: HMG2-related...
75 KB (8,057 words) - 04:44, 25 July 2024
Transcription factor 7-like 2 (T-cell specific, HMG-box), also known as TCF7L2 or TCF4, is a protein acting as a transcription factor that, in humans...
43 KB (4,341 words) - 10:56, 25 July 2024
SOX4 gene. This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic...
11 KB (1,188 words) - 10:22, 25 July 2024
HMG-box transcription factor 1, also known as HBP1, is a human protein. HBP1 has been shown to interact with SIN3A and Retinoblastoma protein. ENSG00000283847...
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The two evolutionarily conserved domains of the protein are HMG-box (high-mobility group box) and the C1 domain: they work together to recognize specific...
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SoxC group is group C of Sry-related HMG box proteins transcription factors. SoxC genes play an important role in determining the cell fate of neuronal...
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PMID 7664264. Lavender P, Vandel L, Bannister AJ, Kouzarides T (June 1997). "The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A"....
79 KB (9,500 words) - 18:16, 10 June 2024
family shares highly conserved DNA binding domains known as HMG (High-mobility group) box domains containing approximately 80 amino acids. Sox2 holds...
29 KB (3,346 words) - 23:18, 17 August 2024
HMG box transcription factor BBX also known as bobby sox homolog or HMG box-containing protein 2 is a protein that in humans is encoded by the BBX gene...
3 KB (401 words) - 06:30, 18 December 2023
almost identical HMG-box DNA-binding domains which function to modify chromatin structure. "Entrez Gene: TOX high mobility group box family member 2"...
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protein FAM227A FBLN1 GTPBP1: GTP-binding protein 1 HMGXB4: encoding protein HMG-box containing 4 IFT27: encoding protein intraflagellar transport 27 IGL@ IGLJ3...
27 KB (2,209 words) - 17:18, 18 August 2024
hypopigmentation syndrome is a condition caused by a mutation on the SRY-related HMG-box gene 10 (not SOX10). It was characterized in 1990, after being seen in...
4 KB (263 words) - 06:20, 5 January 2021