variants of histone H3. These are denoted as Histone H3.1, Histone H3.2, Histone H3.3, Histone H3.4 (H3T), Histone H3.5, Histone H3.X and Histone H3.Y but have...
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designated H1/H5 (linker histones), H2, H3, and H4 (core histones). The nucleosome core is formed of two H2A-H2B dimers and a H3-H4 tetramer. The tight...
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residues of histone proteins. The attachment of methyl groups occurs predominantly at specific lysine or arginine residues on histones H3 and H4. Two...
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of a lysine residue 14 on histone H3 is a tell-tale sign of active transcription. Well characterized modifications to histones include: Methylation: Both...
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H3F3A (redirect from Histone H3.3)
Histone H3.3 is a protein that in humans is encoded by the H3F3A and H3F3B genes. It plays an essential role in maintaining genome integrity during mammalian...
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Histone H3.1 is a protein in humans that is encoded by the H3C1 gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure...
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Nucleosome (redirect from Histone post-translational modification)
called histones, which are known as a histone octamer. Each histone octamer is composed of two copies each of the histone proteins H2A, H2B, H3, and H4...
56 KB (6,714 words) - 12:13, 2 November 2024
a bromodomain, and they are found to acetylate lysine residues on histones H2B, H3, and H4. All members of the GNAT family are characterized by up to...
53 KB (6,150 words) - 04:41, 26 August 2024
H3K4me3 (section Understanding histone modifications)
modification to the DNA packaging protein Histone H3 that indicates tri-methylation at the 4th lysine residue of the histone H3 protein and is often involved in...
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Histone variants are proteins that substitute for the core canonical histones (H3, H4, H2A, H2B) in nucleosomes in eukaryotes and often confer specific...
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NVC community H3, a heath community of the British National Vegetation Classification system Histamine H3 receptor, a human gene Histone H3, a component...
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residues of the H3 and H4 histones. There are instances of the core globular domains of histones being methylated as well. The histone methyltransferases...
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task. Histone methylation can cause transcription repression. Lysine can undergo mono-, di- and tri-methylation. Di- and tri-methylation of histone H3 at...
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Epigenetics (section Histone modifications)
For example, acetylation of the K14 and K9 lysines of the tail of histone H3 by histone acetyltransferase enzymes (HATs) is generally related to transcriptional...
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H3K27ac (section Histone modifications)
packaging protein histone H3. It is a mark that indicates acetylation of the lysine residue at N-terminal position 27 of the histone H3 protein. H3K27ac...
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other histone proteins are: H1, H2B, H3 and H4. Histones are proteins that package DNA into nucleosomes. Histones are responsible for maintaining the shape...
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H3K9ac (section Histone modifications)
packaging protein Histone H3. It is a mark that indicates the acetylation at the 9th lysine residue of the histone H3 protein. The H3K9 histone has two jobs...
20 KB (1,748 words) - 06:32, 11 January 2024
each of the four core histone proteins (H2A, H2B, H3, and H4). The octamer assembles when a tetramer, containing two copies of H3 and two of H4, complexes...
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H3K9me2 (section Understanding histone modifications)
the DNA packaging protein Histone H3. It is a mark that indicates the di-methylation at the 9th lysine residue of the histone H3 protein. H3K9me2 is strongly...
40 KB (2,617 words) - 04:48, 3 July 2024
H3K9me3 (section Understanding histone modifications)
DNA packaging protein Histone H3. It is a mark that indicates the tri-methylation at the 9th lysine residue of the histone H3 protein and is often associated...
16 KB (1,216 words) - 23:09, 11 April 2024
H3K27me3 (section Understanding histone modifications)
modification to the DNA packaging protein histone H3. It is a mark that indicates the tri-methylation of lysine 27 on histone H3 protein. This tri-methylation is...
28 KB (2,629 words) - 18:35, 18 September 2024
H3K36me3 (redirect from H3.3K36me3)
DNA packaging protein Histone H3. It is a mark that indicates the tri-methylation at the 36th lysine residue of the histone H3 protein and often associated...
19 KB (1,519 words) - 23:11, 11 April 2024
components of chromatin are histones. An octamer of two sets of four histone cores (Histone H2A, Histone H2B, Histone H3, and Histone H4) bind to DNA and function...
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is a protein which in humans is encoded by the CENPA gene. CENPA is a histone H3 variant which is the critical factor determining the kinetochore position(s)...
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Demethylase (redirect from Histone lysine demethylase)
Tolstorukov MY, Farcas AM, Park PJ, Klose RJ (Apr 2010). "CpG islands recruit a histone H3 lysine 36 demethylase". Molecular Cell. 38 (2): 179–90. doi:10.1016/j...
25 KB (3,087 words) - 22:52, 3 December 2023
protein complexes called histone cores. These histone cores are composed of 8 subunits, two each of H2A, H2B, H3 and H4 histones. This protein complex forms...
58 KB (7,036 words) - 21:48, 28 February 2024
safely store the eukaryotic genome, DNA is wrapped around four core histone proteins (H3, H4, H2A, H2B), which then join to form nucleosomes. These nucleosomes...
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H3F3B (gene) (redirect from H3-3B)
Histone H3.3 is a protein that in humans is encoded by the H3-3A, and the H3-3B genes. Histones are basic nuclear proteins that are responsible for the...
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H3K4me1 (section Understanding histone modifications)
DNA packaging protein Histone H3. It is a mark that indicates the mono-methylation at the 4th lysine residue of the histone H3 protein and often associated...
19 KB (1,611 words) - 23:11, 11 April 2024