are known, 2-imidazolines, 3-imidazolines, and 4-imidazolines. The 2- and 3-imidazolines contain an imine center, whereas the 4-imidazolines contain an...

Imidazoline receptors are the primary receptors on which clonidine and other imidazolines act. There are three main classes of imidazoline receptor: I1...

2-Imidazoline (Preferred IUPAC name: 4,5-dihydro-1H-imidazole) is one of three isomers of the nitrogen-containing heterocycle imidazoline, with the formula...

peripheral vasomotor structures. Rilmenidine shows greater selectivity for imidazoline receptors than for cerebral alpha2-adrenergic receptors, distinguishing...

Moxonidine (INN) is a new-generation alpha-2/imidazoline receptor agonist antihypertensive drug licensed for the treatment of mild to moderate essential...

example of autoreceptor. However, it is now known that clonidine binds to imidazoline receptors with a much greater affinity than α2 receptors, which would...

symptoms). Selected examples are: Clonidine (mixed alpha2-adrenergic and imidazoline-I1 receptor agonist) Dexmedetomidine Fadolmidine Guanfacine, (preference...

ingested the drug. There is no antidote for tetryzoline or other similar imidazoline analogue poisoning, but the symptoms can be alleviated. With treatment...

targets: Neurotransmitter receptors and receptor ionophores. Nicotinic, imidazoline I1 and I2, α2-adrenergic, glutamate NMDAr, and serotonin 5-HT2A and 5HT-3...

vascular resistance.: 201–203  Clonidine also acts as an agonist at imidazoline-1 (I1) receptors in the brain, and it is hypothesized that this effect...

selective α2 adrenergic receptor antagonist, and an antagonist for the imidazoline receptor. Idazoxan has been under investigation as an antidepressant...

certain oral medications (e.g., sympathomimetic amines and various 2-imidazolines) that constrict blood vessels in the lining of the nose, although evidence...

Benzimidazole, an analog with a fused benzene ring Dihydroimidazole or imidazoline, an analog where the 4,5-double bond is saturated Pyrrole, an analog...

2868802A, Hüni, Albrecht, "2-(γ-TERT-BUTYL-O,O'-DIMETHYL-PHENYL-METHYL)-IMIDAZOLINE AND SALTS", issued 1959-01-13, assigned to Ciba Pharmaceutical Products...

(NAR) up to 35.7% and reduce nasal mucosal blood flow up to 50%. Since imidazolines are sympathomimetic agents, their primary effects appear on α adrenergic...

molecule: Amino acids (Arg) Arginine Arg, R α2-Adrenergic receptors, imidazoline receptors NMDA receptors Small: Amino acids Aspartate Asp, D – NMDA receptors...

ATC code C02 Antihypertensives is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed...

Tolonidine is an antihypertensive. It is an imidazoline receptor agonist, like moxonidine and rilmenidine. Clonidine Cosnier, D.; Duchene-Marullaz, P...

the σ1 receptor (Ki = 3.2 nM) and with very high affinity to the I2 imidazoline receptor (Ki = 40 pM). Clorgiline is also a multidrug efflux pump inhibitor...

W.C.; Liu, I.M.; Chung, H.H.; Cheng, J.T. (2008). "Activation of I2-imidazoline receptors may ameliorate insulin resistance in fructose-rich chow-fed...

receptor modulators Nicotinic acetylcholine receptor modulators Others: Imidazoline receptor modulators Purine receptor modulators Sigma receptor modulators...

easily. Cationic emulsifiers primarily include long-chain amines such as imidazolines, amido-amines, and diamines, which acquire a positive charge when an...

Nutlins are cis-imidazoline analogs which inhibit the interaction between mdm2 and tumor suppressor p53, and which were discovered by screening a chemical...

ATC code C04 Peripheral vasodilators is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes...

fungicides under the brand names Maneb, Mancozeb, Zineb, and Metiram. Some imidazoline-containing fungicides are derived from ethylenediamine. Ethylenediamine...

receptor agonists agomelatine, melatonin, ramelteon, tasimelteon Imidazoline receptor Imidazoline receptor agonists apraclonidine, clonidine, moxonidine, rilmenidine...

α2A-adrenergic receptor but also α2B- and α2C-adrenergic receptors and the imidazoline receptor. It is weaker than clonidine in producing hypotension and sedation...

affinity and substantially reduces DAT and SERT affinity. Expansion of the imidazoline ring system in mazindol to the corresponding six-membered homolog increases...

↑intracellular Ca2+ → ↑NOS activity → ↑NO → (see nitric oxide) L-arginine imidazoline and α-2 receptor? Gi → ↓cAMP → activation of Na+/K+-ATPase → ↓intracellular...

Products containing nicotine such as cigarettes, chewing tobacco or gum Imidazolines such as clonidine, naphazoline, oxymetazoline and tetrahydrozoline Antipsychotics...