Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore. Their functions include establishing a resting membrane...
44 KB (5,175 words) - 04:08, 10 September 2024
Ligand-gated ion channels (LICs, LGIC), also commonly referred to as ionotropic receptors, are a group of transmembrane ion-channel proteins which open...
29 KB (2,597 words) - 03:43, 7 April 2024
Voltage-gated ion channels are a class of transmembrane proteins that form ion channels that are activated by changes in a cell's electrical membrane...
21 KB (2,298 words) - 12:09, 9 August 2024
Potassium channels are the most widely distributed type of ion channel found in virtually all organisms. They form potassium-selective pores that span...
57 KB (5,829 words) - 23:54, 16 July 2024
Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's membrane. They belong to the superfamily...
51 KB (5,597 words) - 08:29, 23 July 2024
Synthetic ion channels are de novo chemical compounds that insert into lipid bilayers, form pores, and allow ions to flow from one side to the other....
30 KB (3,035 words) - 23:30, 16 July 2024
calcium channel is an ion channel which shows selective permeability to calcium ions. It is sometimes synonymous with voltage-gated calcium channel, which...
10 KB (760 words) - 22:20, 16 July 2024
Membrane potential (section Ion channels)
the membrane, and ion channels allow ions to move across the membrane down those concentration gradients. Ion pumps and ion channels are electrically equivalent...
64 KB (8,202 words) - 08:03, 15 September 2024
Mechanosensitive channels (MSCs), mechanosensitive ion channels or stretch-gated ion channels are membrane proteins capable of responding to mechanical...
66 KB (7,825 words) - 22:28, 16 July 2024
Voltage-gated sodium channels (VGSCs), also known as voltage-dependent sodium channels (VDSCs), are a group of voltage-gated ion channels found in the membrane...
34 KB (3,587 words) - 12:35, 24 June 2024
Ion Plus is an American broadcast television network and FAST television channel owned by the Scripps Networks subsidiary of the E. W. Scripps Company...
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of the channels has been implicated in several diseases. IRK channels possess a pore domain, homologous to that of voltage-gated ion channels, and flanking...
22 KB (2,007 words) - 01:49, 26 March 2024
Ion Television (referred to on-air as simply Ion) is an American broadcast television network and FAST television channel owned by the Scripps Networks...
89 KB (11,369 words) - 13:48, 7 September 2024
structures embedded in the membrane called ion pumps and ion channels. In neurons, the types of ion channels in the membrane usually vary across different...
149 KB (16,431 words) - 05:24, 30 July 2024
nucleotide–gated ion channels or CNG channels are ion channels that function in response to the binding of cyclic nucleotides. CNG channels are nonselective...
39 KB (4,913 words) - 23:11, 11 January 2024
voltage-gated ion channels) and can act to open or close the channel. The pore formed by an ion channel is aqueous (water-filled) and allows the ion to rapidly...
46 KB (5,430 words) - 18:10, 24 April 2024
Channelopathy (redirect from Ion channelopathy)
Channelopathies are a group of diseases caused by the dysfunction of ion channel subunits or their interacting proteins. These diseases can be inherited...
14 KB (1,120 words) - 04:48, 30 August 2024
A channel blocker is the biological mechanism in which a particular molecule is used to prevent the opening of ion channels in order to produce a physiological...
26 KB (3,020 words) - 11:51, 16 January 2024
Barbiturate (category Calcium channel blockers)
ligand-gated ion channels, of which the GABAA receptor channel is only one of several representatives. This Cys-loop receptor superfamily of ion channels includes...
44 KB (4,711 words) - 08:01, 14 September 2024
currents will also result in a hyperpolarization. This voltage-gated ion channel response is how the hyperpolarization state is achieved. In neurons,...
9 KB (1,079 words) - 05:36, 13 October 2022
in channel selectivity. Chloride ion channels vary from many other ion channels due to being controlled by the anionic chloride ions. Chloride ion channels...
10 KB (1,163 words) - 06:29, 26 July 2023
sodium channel (ENaC), (also known as amiloride-sensitive sodium channel) is a membrane-bound ion channel that is selectively permeable to sodium ions (Na+)...
25 KB (2,956 words) - 20:54, 27 June 2024
The transmembrane cation channel superfamily was defined in InterPro and Pfam as the family of tetrameric ion channels. These include the sodium, potassium...
19 KB (1,692 words) - 03:53, 29 November 2023
Graded potential (section Ligand-gated ion channels)
ligand-gated ion channel proteins, and decrease over time and space. They do not typically involve voltage-gated sodium and potassium channels, but rather...
6 KB (736 words) - 18:59, 17 November 2023
An ion (/ˈaɪ.ɒn, -ən/) is an atom or molecule with a net electrical charge. The charge of an electron is considered to be negative by convention and this...
31 KB (3,168 words) - 02:41, 12 September 2024
referred to as two-pore channels". Below is a list of the 15 known two-pore-domain human potassium channels: Ion channel Potassium channel Goldstein SA, Bayliss...
9 KB (690 words) - 04:16, 23 November 2023
G protein-gated ion channels are a family of transmembrane ion channels in neurons and atrial myocytes that are directly gated by G proteins. Generally...
30 KB (3,706 words) - 21:03, 30 December 2023
channel modulator, or ion channel modulator, is a type of drug which modulates ion channels. They include channel blockers and channel openers. Ion channels...
3 KB (296 words) - 01:33, 5 October 2023
electrical signal, by regulating the activity of ion channels. The influx of ions through ion channels opened due to the binding of neurotransmitters to...
16 KB (1,590 words) - 01:49, 26 October 2023
David Colquhoun (section Work with single ion channels)
synaptic mechanisms, and in particular the theory and practice of single ion channel function. He held the A.J. Clark chair of Pharmacology at UCL from 1985...
33 KB (3,511 words) - 15:34, 26 August 2024