Myostatin (also known as growth differentiation factor 8, abbreviated GDF8) is a protein that in humans is encoded by the MSTN gene. Myostatin is a myokine...

Myostatin inhibitors are a class of drugs that work by blocking the effects of myostatin, which inhibits muscle growth. In animal models and limited human...

Myostatin-related muscle hypertrophy is a rare genetic condition characterized by reduced body fat and increased skeletal muscle size. Affected individuals...

natural mutation in the myostatin gene which codes for the protein, myostatin ("myo" meaning muscle and "statin" meaning stop). Myostatin is a protein that...

known mutations that limits and reduces the activity of the myostatin protein. Normally, myostatin limits the number of muscle fibers present at birth, and...

injury/inflammation in response to stress) are increased in sarcopenic obesity. Myostatin is also increased. In the fat, lipotoxicity and chronic inflammation are...

identified a natural variant of the myostatin gene found in Limousins which has a significant influence on them. The myostatin gene is found in all mammals and...

the term myokine first occurred in 2003. In 2008, the first myokine, myostatin, was identified. The gp130 receptor cytokine IL-6 (Interleukin 6) was...

Piedmontese cattle carry a unique gene mutation identified as an inactive myostatin allele that causes hypertrophic muscle growth, or double muscling. Purebred...

amount of myostatin portray deficiency in muscle development and increase of fat; on the other hand, smaller than normal amounts of myostatin greatly increase...

PMID 23995658. Lee SJ, Gharbi A, Shin JE, Jung ID, Park YM (March 2021). "Myostatin inhibitor YK11 as a preventative health supplement for bacterial sepsis"...

Stamulumab (MYO-029) is an experimental myostatin inhibiting drug developed by Wyeth Pharmaceuticals for the treatment of muscular dystrophy (MD). Stamulumab...

naturally occurring gene identified as the myostatin allele mutation, or inactive myostatin gene. Myostatin prohibits muscle growth whereas an inactive...

second leading cause of mortality in Whippets. A 2007 study identified a myostatin mutation particular to Whippets that is significantly associated with...

small interfering RNA. Myostatin is a protein responsible for inhibiting muscle differentiation and growth. Removing the myostatin gene or otherwise limiting...

its role in regulation of muscle growth in mice, as an antagonist to myostatin (also known as GDF-8, a TGF superfamily member) which inhibits excessive...

binds to myostatin, it lowers the amount of myostatin that can bind to the native receptor in the membrane (ActRIIB), preventing myostatin from delivering...

precursor to myostatin, which limits the size of skeletal muscle tissue, as well as inactive myostatin. It does not bind to active myostatin, activin A...

(Drm) LTBP1 Noggin TGIF Thrombospondin 1 (THBS1) Tomoregulin 1 Antibodies: Stamulumab (against myostatin) TRC105 (against endoglin) Others: Endoglin...

; McPherron, Alexandra C. (October 2011). "Expression and Function of Myostatin in Obesity, Diabetes, and Exercise Adaptation". Medicine and Science in...

monoclonal antibody that blocks the activation of the skeletal muscle protein myostatin, thereby promoting muscle tissue growth. As of 2021, the molecule showed...

to myostatin, a negative regulator of muscle growth, both structurally and phylogenetically. Though GDF11 is 90% structurally similar to myostatin, GDF11's...

total carcass fat—especially seam fat. A mutation in the 3' UTR of the myostatin gene in Texel sheep creates target sites for the microRNAs miR-1 and miR-206...

2013). "Hyperammonemia in cirrhosis induces transcriptional regulation of myostatin by an NF-κB–mediated mechanism". Proceedings of the National Academy of...

receptors regulate muscle growth. Myostatin, a TGF-beta superfamily member, is a negative regulator of muscle growth. Myostatin binds to ACVR2B and to a lesser...

Library of Medicine. Lee SJ, Gharbi A, Shin JE, Jung ID, Park YM (2021). "Myostatin inhibitor YK11 as a preventative health supplement for bacterial sepsis"...

may refer to: Kocher–Debré–Semelaigne syndrome Adrenogenital syndrome Myostatin mutation resulting in hypertrophy and increased strength This disambiguation...

follicle-stimulating hormone; it also has many other systemic effects. Myocytes use myostatin to tell each other to inhibit myogenesis. Melanocyte-inhibiting factor...

(Drm) LTBP1 Noggin TGIF Thrombospondin 1 (THBS1) Tomoregulin 1 Antibodies: Stamulumab (against myostatin) TRC105 (against endoglin) Others: Endoglin...

protein (MSP), also known as hepatocyte growth factor-like protein (HGFLP) Myostatin (GDF-8) Neuregulins Neuregulin 1 (NRG1) Neuregulin 2 (NRG2) Neuregulin...