• Nucleophile (redirect from Nucleophilicity)
    nucleophilic substitution, whereby a nucleophile becomes attracted to a full or partial positive charge, and nucleophilic addition. Nucleophilicity is...
    18 KB (2,190 words) - 20:08, 25 November 2024
  • In chemistry, a nucleophilic substitution (SN) is a class of chemical reactions in which an electron-rich chemical species (known as a nucleophile) replaces...
    12 KB (1,415 words) - 13:08, 26 August 2024
  • Thumbnail for SN2 reaction
    The bimolecular nucleophilic substitution (SN2) is a type of reaction mechanism that is common in organic chemistry. In the SN2 reaction, a strong nucleophile...
    21 KB (2,555 words) - 19:00, 17 December 2024
  • In organic chemistry, a nucleophilic addition (AN) reaction is an addition reaction where a chemical compound with an electrophilic double or triple bond...
    8 KB (910 words) - 13:13, 26 August 2024
  • Thumbnail for Nucleophilic aromatic substitution
    Aromatic rings are usually nucleophilic, but some aromatic compounds do undergo nucleophilic substitution. Just as normally nucleophilic alkenes can be made...
    11 KB (1,295 words) - 06:15, 27 December 2024
  • Nucleophilic abstraction is a type of an organometallic reaction which can be defined as a nucleophilic attack on a ligand which causes part or all of...
    6 KB (807 words) - 15:35, 29 March 2024
  • reactions in organic chemistry are classified either as electrophilic or nucleophilic depending upon the reagent involved, whether a reactive intermediate...
    12 KB (1,456 words) - 13:55, 26 August 2024
  • Thumbnail for Catalytic triad
    β-lactamases). An acid-base-nucleophile triad is a common motif for generating a nucleophilic residue for covalent catalysis. The residues form a charge-relay network...
    57 KB (5,838 words) - 22:13, 1 December 2024
  • The unimolecular nucleophilic substitution (SN1) reaction is a substitution reaction in organic chemistry. The Hughes-Ingold symbol of the mechanism expresses...
    15 KB (1,970 words) - 03:54, 24 October 2024
  • Thumbnail for Acyl group
    esters, and amides. Carboxylate ions are essentially unreactive towards nucleophilic substitution, since they possess no leaving group. The reactivity of...
    18 KB (1,913 words) - 21:16, 5 November 2024
  • Radical-nucleophilic aromatic substitution or SRN1 in organic chemistry is a type of substitution reaction in which a certain substituent on an aromatic...
    4 KB (454 words) - 19:31, 27 October 2022
  • As the name suggests, a non-nucleophilic base is a sterically hindered organic base that is a poor nucleophile. Normal bases are also nucleophiles, but...
    3 KB (354 words) - 02:44, 22 March 2024
  • Thumbnail for Nucleophilic conjugate addition
    Nucleophilic conjugate addition is a type of organic reaction. Ordinary nucleophilic additions or 1,2-nucleophilic additions deal mostly with additions...
    6 KB (625 words) - 20:20, 5 March 2024
  • Thumbnail for Alkylation
    dealkylation. Alkylating agents are often classified according to their nucleophilic or electrophilic character. In oil refining contexts, alkylation refers...
    15 KB (1,651 words) - 13:59, 24 August 2024
  • Thumbnail for Vicarious nucleophilic substitution
    In organic chemistry, the vicarious nucleophilic substitution is a special type of nucleophilic aromatic substitution in which a nucleophile replaces...
    2 KB (182 words) - 19:34, 27 October 2022
  • Thumbnail for Aromatic compound
    due to high C:H ratio Undergo electrophilic substitution reactions and nucleophilic aromatic substitutions Arenes are typically split into two categories...
    21 KB (2,120 words) - 04:56, 12 January 2025
  • Thumbnail for Ketone
    electronegativity of the oxygen is greater than that for carbon. Thus, ketones are nucleophilic at oxygen and electrophilic at carbon. Because the carbonyl group interacts...
    24 KB (2,895 words) - 01:11, 8 January 2025
  • Nucleophilic epoxidation is the formation of epoxides from electron-deficient double bonds through the action of nucleophilic oxidants. Nucleophilic epoxidation...
    14 KB (1,634 words) - 16:11, 7 March 2021
  • Thumbnail for Ether
    intramolecular nucleophilic substitution of a halohydrin. Many ethers, ethoxylates and crown ethers, are produced from epoxides. Nucleophilic displacement...
    19 KB (1,843 words) - 18:54, 16 December 2024
  • Thumbnail for Chemical reaction
    electron density and enter nucleophilic aromatic substitution only with very strong electron withdrawing groups. Nucleophilic substitution can take place...
    66 KB (8,043 words) - 01:08, 14 October 2024
  • Thumbnail for SNi
    (substitution nucleophilic internal) refers to a specific, regio-selective but not often encountered reaction mechanism for nucleophilic aliphatic substitution...
    5 KB (514 words) - 15:18, 27 December 2024
  • S2CID 4326584. Bender ML (1 January 1962). "Metal Ion Catalysis of Nucleophilic Organic Reactions in Solution". Reactions of Coordinated Ligands. Advances...
    43 KB (5,001 words) - 18:45, 7 August 2024
  • Thumbnail for Alcohol (chemistry)
    Primary alkyl halides react with aqueous NaOH or KOH to give alcohols in nucleophilic aliphatic substitution. Secondary and especially tertiary alkyl halides...
    35 KB (3,855 words) - 08:18, 21 November 2024
  • reactive. Their reactivity can be classified in three main classes: (1) nucleophilic additions, (2) pericyclic reactions, and (3) bond-insertion. Upon treatment...
    28 KB (3,128 words) - 04:03, 9 November 2024
  • Thumbnail for Amino sugar
    with glycosidic bond formation at the same time in a one-pot procedure. Nucleophilic displacement can be an effective strategy for the synthesis of amino...
    6 KB (732 words) - 17:50, 11 August 2024
  • Thumbnail for Maillard reaction
    pronounced. The reactive carbonyl group of the sugar reacts with the nucleophilic amino group of the amino acid and forms a complex mixture of poorly characterized...
    15 KB (1,566 words) - 15:08, 27 December 2024
  • In organic chemistry, vinylation is the process of attaching a vinyl group (CH2=CH−) to a substrate. Many organic compounds contain vinyl groups, so the...
    6 KB (602 words) - 21:23, 21 July 2024
  • substitution Nucleophilic aromatic substitution Electrophilic substitution Nucleophilic substitution SN1 reaction SN2 reaction Vicarious nucleophilic substitution...
    8 KB (576 words) - 12:14, 30 October 2023
  • product mixture. Methylation sometimes involve use of nucleophilic methyl reagents. Strongly nucleophilic methylating agents include methyllithium (CH3Li)...
    28 KB (3,059 words) - 12:32, 12 January 2025
  • Thumbnail for Aldehyde
    tautomer in strong acid or base solutions, and enolized aldehydes undergo nucleophilic attack at the α position. The formyl group can be readily reduced to...
    30 KB (3,092 words) - 03:52, 26 December 2024