A peroxisome (IPA: [pɛɜˈɹɒksɪˌsoʊm]) is a membrane-bound organelle, a type of microbody, found in the cytoplasm of virtually all eukaryotic cells. Peroxisomes...
33 KB (3,863 words) - 06:13, 27 July 2024
In the field of molecular biology, the peroxisome proliferator–activated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription...
18 KB (1,897 words) - 23:57, 4 October 2024
Peroxisome proliferator-activated receptor gamma (PPAR-γ or PPARG), also known as the glitazone reverse insulin resistance receptor, or NR1C3 (nuclear...
19 KB (2,091 words) - 05:22, 13 July 2024
Peroxisome proliferator-activated receptor alpha (PPAR-α), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor...
22 KB (2,567 words) - 20:42, 4 October 2024
Peroxisomal disorder (redirect from Peroxisome biogenesis disorders)
conditions caused by defects in peroxisome functions. This may be due to defects in single enzymes important for peroxisome function or in peroxins, proteins...
8 KB (578 words) - 19:15, 22 July 2024
Peroxisome proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that...
18 KB (1,964 words) - 09:49, 12 October 2024
renin–angiotensin system, telmisartan acts as a selective modulator of peroxisome proliferator-activated receptor gamma (PPAR-γ), a central regulator of...
14 KB (1,192 words) - 05:32, 13 September 2024
In enzymology, a peroxisome-assembly ATPase (EC 3.6.4.7) is an enzyme that catalyzes the chemical reaction ATP + H2O ⇌ {\displaystyle \rightleftharpoons...
3 KB (221 words) - 15:20, 26 August 2023
PPAR agonist (redirect from Peroxisome proliferator-activated receptor agonist)
PPAR agonists are drugs which act upon the peroxisome proliferator-activated receptor. They are used for the treatment of symptoms of the metabolic syndrome...
9 KB (1,045 words) - 20:41, 4 October 2024
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) is a protein that in humans is encoded by the PPARGC1A gene. PPARGC1A is...
31 KB (3,777 words) - 20:49, 25 September 2024
congenital disorder characterized by the reduction or absence of functional peroxisomes in the cells of an individual. It is one of a family of disorders called...
14 KB (1,378 words) - 09:58, 25 July 2024
Microbody (section Peroxisomes)
plants, protozoa, and animals. Organelles in the microbody family include peroxisomes, glyoxysomes, glycosomes and hydrogenosomes. In vertebrates, microbodies...
4 KB (490 words) - 22:29, 11 February 2024
lowered very-low-density lipoprotein (VLDL). Acadesine GFT505 GW0742 Irisin Peroxisome proliferator-activated receptor Sodelglitazar SR9009 Koh B (2013-03-22)...
20 KB (1,953 words) - 10:00, 20 October 2024
heterotopia 7 Perlman syndrome Peroxisome biogenesis disorder 10A (Zellweger) Peroxisome biogenesis disorder 13A (Zellweger) Peroxisome biogenesis disorder 1A...
14 KB (1,343 words) - 23:07, 16 October 2024
contraindicated due to an increased risk of rhabdomyolysis. Fibrates stimulate peroxisome proliferator activated receptor (PPAR) alpha, which controls the expression...
10 KB (1,091 words) - 01:14, 8 October 2024
mitochondrial membrane, although very long chain fatty acids are oxidized in peroxisomes. The overall reaction for one cycle of beta oxidation is: Cn-acyl-CoA...
32 KB (3,377 words) - 04:07, 4 September 2024
antidiabetic drug, and has anti-inflammatory effects. GW501516 Elafibranor Peroxisome proliferator-activated receptor "Cayman Chemical GW0742". Retrieved 31...
9 KB (827 words) - 19:19, 6 May 2024
Christian de Duve (section Discovery of peroxisome)
biochemist. He made serendipitous discoveries of two cell organelles, peroxisomes and lysosomes, for which he shared the Nobel Prize in Physiology or Medicine...
49 KB (5,605 words) - 14:20, 23 October 2024
mortality. PFOA alters lipid metabolism. It is an agonist of PPARα and is a peroxisome proliferator in rodents contributing to a well understood form of oxidative...
127 KB (13,076 words) - 18:19, 17 September 2024
acid linked to an isopropyl ester. It lowers lipid levels by activating peroxisome proliferator-activated receptor alpha (PPARα). PPARα activates lipoprotein...
26 KB (2,514 words) - 21:09, 28 September 2024
component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with...
11 KB (1,407 words) - 11:53, 24 December 2023
biogenesis factor 11 (PEX11) are peroxisomal membrane proteins which promote peroxisome division in eukaryotic cells. PEX11A PEX11B PEX11G Gould SJ, Smith KD...
1 KB (95 words) - 07:15, 16 April 2022
and rosiglitazone. Thiazolidinediones or TZDs act by activating PPARs (peroxisome proliferator-activated receptors), a group of nuclear receptors, specific...
20 KB (2,167 words) - 15:13, 20 September 2024
proconvulsively. Another potential target of antiepileptic drugs is the peroxisome proliferator-activated receptor alpha. Some anticonvulsants have shown...
70 KB (5,714 words) - 11:37, 30 September 2024
Glyoxysomes are specialized peroxisomes found in plants (particularly in the fat storage tissues of germinating seeds) and also in filamentous fungi....
2 KB (242 words) - 21:18, 8 June 2024
this condition involves a defect in PEX7, whose product is involved in peroxisome assembly. There are 3 pathways that depend on peroxisomal biogenesis factor...
10 KB (727 words) - 16:52, 26 August 2024
increasing lipoprotein triglyceride lipolysis. It does so by activating peroxisome proliferator-activated receptor alpha (PPARα) 'transcription factor ligand'...
12 KB (950 words) - 06:13, 1 April 2024
Peroxisome biogenesis factor 1, also known as PEX1, is a protein which in humans is encoded by the PEX1 gene. This gene encodes a member of the AAA protein...
11 KB (1,212 words) - 07:43, 4 January 2024
buprenorphine, nalmefene and norclozapine. Examples of ligands activating peroxisome proliferator-activated receptor gamma as partial agonists are honokiol...
4 KB (429 words) - 04:01, 14 February 2024
syngamy), a dormant cyst with a cell wall of chitin or cellulose, and peroxisomes. An endosymbiotic union between a motile anaerobic archaean and an aerobic...
61 KB (6,102 words) - 11:22, 19 October 2024