• Thumbnail for Peroxisome
    A peroxisome (IPA: [pɛɜˈɹɒksɪˌsoʊm]) is a membrane-bound organelle, a type of microbody, found in the cytoplasm of virtually all eukaryotic cells. Peroxisomes...
    33 KB (3,863 words) - 06:13, 27 July 2024
  • Thumbnail for Peroxisome proliferator-activated receptor
    In the field of molecular biology, the peroxisome proliferator–activated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription...
    18 KB (1,897 words) - 23:57, 4 October 2024
  • Thumbnail for Peroxisome proliferator-activated receptor gamma
    Peroxisome proliferator-activated receptor gamma (PPAR-γ or PPARG), also known as the glitazone reverse insulin resistance receptor, or NR1C3 (nuclear...
    19 KB (2,091 words) - 05:22, 13 July 2024
  • Thumbnail for Peroxisome proliferator-activated receptor alpha
    Peroxisome proliferator-activated receptor alpha (PPAR-α), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor...
    22 KB (2,567 words) - 20:42, 4 October 2024
  • Thumbnail for Peroxisomal disorder
    conditions caused by defects in peroxisome functions. This may be due to defects in single enzymes important for peroxisome function or in peroxins, proteins...
    8 KB (578 words) - 19:15, 22 July 2024
  • Thumbnail for Peroxisome proliferator-activated receptor delta
    Peroxisome proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that...
    18 KB (1,964 words) - 09:49, 12 October 2024
  • Thumbnail for Telmisartan
    renin–angiotensin system, telmisartan acts as a selective modulator of peroxisome proliferator-activated receptor gamma (PPAR-γ), a central regulator of...
    14 KB (1,192 words) - 05:32, 13 September 2024
  • In enzymology, a peroxisome-assembly ATPase (EC 3.6.4.7) is an enzyme that catalyzes the chemical reaction ATP + H2O ⇌ {\displaystyle \rightleftharpoons...
    3 KB (221 words) - 15:20, 26 August 2023
  • Thumbnail for PPAR agonist
    PPAR agonists are drugs which act upon the peroxisome proliferator-activated receptor. They are used for the treatment of symptoms of the metabolic syndrome...
    9 KB (1,045 words) - 20:41, 4 October 2024
  • Thumbnail for Pparg coactivator 1 alpha
    Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) is a protein that in humans is encoded by the PPARGC1A gene. PPARGC1A is...
    31 KB (3,777 words) - 20:49, 25 September 2024
  • Thumbnail for Zellweger syndrome
    congenital disorder characterized by the reduction or absence of functional peroxisomes in the cells of an individual. It is one of a family of disorders called...
    14 KB (1,378 words) - 09:58, 25 July 2024
  • plants, protozoa, and animals. Organelles in the microbody family include peroxisomes, glyoxysomes, glycosomes and hydrogenosomes. In vertebrates, microbodies...
    4 KB (490 words) - 22:29, 11 February 2024
  • Thumbnail for GW501516
    lowered very-low-density lipoprotein (VLDL). Acadesine GFT505 GW0742 Irisin Peroxisome proliferator-activated receptor Sodelglitazar SR9009 Koh B (2013-03-22)...
    20 KB (1,953 words) - 10:00, 20 October 2024
  • Thumbnail for Micrognathism
    heterotopia 7 Perlman syndrome Peroxisome biogenesis disorder 10A (Zellweger) Peroxisome biogenesis disorder 13A (Zellweger) Peroxisome biogenesis disorder 1A...
    14 KB (1,343 words) - 23:07, 16 October 2024
  • Thumbnail for Fibrate
    contraindicated due to an increased risk of rhabdomyolysis. Fibrates stimulate peroxisome proliferator activated receptor (PPAR) alpha, which controls the expression...
    10 KB (1,091 words) - 01:14, 8 October 2024
  • mitochondrial membrane, although very long chain fatty acids are oxidized in peroxisomes. The overall reaction for one cycle of beta oxidation is: Cn-acyl-CoA...
    32 KB (3,377 words) - 04:07, 4 September 2024
  • Thumbnail for GW0742
    antidiabetic drug, and has anti-inflammatory effects. GW501516 Elafibranor Peroxisome proliferator-activated receptor "Cayman Chemical GW0742". Retrieved 31...
    9 KB (827 words) - 19:19, 6 May 2024
  • Thumbnail for Christian de Duve
    biochemist. He made serendipitous discoveries of two cell organelles, peroxisomes and lysosomes, for which he shared the Nobel Prize in Physiology or Medicine...
    49 KB (5,605 words) - 14:20, 23 October 2024
  • Thumbnail for Perfluorooctanoic acid
    mortality. PFOA alters lipid metabolism. It is an agonist of PPARα and is a peroxisome proliferator in rodents contributing to a well understood form of oxidative...
    127 KB (13,076 words) - 18:19, 17 September 2024
  • Thumbnail for Fenofibrate
    acid linked to an isopropyl ester. It lowers lipid levels by activating peroxisome proliferator-activated receptor alpha (PPARα). PPARα activates lipoprotein...
    26 KB (2,514 words) - 21:09, 28 September 2024
  • Thumbnail for PEX14
    component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with...
    11 KB (1,407 words) - 11:53, 24 December 2023
  • biogenesis factor 11 (PEX11) are peroxisomal membrane proteins which promote peroxisome division in eukaryotic cells. PEX11A PEX11B PEX11G Gould SJ, Smith KD...
    1 KB (95 words) - 07:15, 16 April 2022
  • Thumbnail for Thiazolidinedione
    and rosiglitazone. Thiazolidinediones or TZDs act by activating PPARs (peroxisome proliferator-activated receptors), a group of nuclear receptors, specific...
    20 KB (2,167 words) - 15:13, 20 September 2024
  • proconvulsively. Another potential target of antiepileptic drugs is the peroxisome proliferator-activated receptor alpha. Some anticonvulsants have shown...
    70 KB (5,714 words) - 11:37, 30 September 2024
  • Glyoxysomes are specialized peroxisomes found in plants (particularly in the fat storage tissues of germinating seeds) and also in filamentous fungi....
    2 KB (242 words) - 21:18, 8 June 2024
  • Thumbnail for Rhizomelic chondrodysplasia punctata
    this condition involves a defect in PEX7, whose product is involved in peroxisome assembly. There are 3 pathways that depend on peroxisomal biogenesis factor...
    10 KB (727 words) - 16:52, 26 August 2024
  • Thumbnail for Gemfibrozil
    increasing lipoprotein triglyceride lipolysis. It does so by activating peroxisome proliferator-activated receptor alpha (PPARα) 'transcription factor ligand'...
    12 KB (950 words) - 06:13, 1 April 2024
  • Thumbnail for PEX1
    Peroxisome biogenesis factor 1, also known as PEX1, is a protein which in humans is encoded by the PEX1 gene. This gene encodes a member of the AAA protein...
    11 KB (1,212 words) - 07:43, 4 January 2024
  • Thumbnail for Partial agonist
    buprenorphine, nalmefene and norclozapine. Examples of ligands activating peroxisome proliferator-activated receptor gamma as partial agonists are honokiol...
    4 KB (429 words) - 04:01, 14 February 2024
  • Thumbnail for Eukaryote
    syngamy), a dormant cyst with a cell wall of chitin or cellulose, and peroxisomes. An endosymbiotic union between a motile anaerobic archaean and an aerobic...
    61 KB (6,102 words) - 11:22, 19 October 2024