Spironolactone, sold under the brand name Aldactone among others, is a diuretic medication primarily used to treat fluid build-up due to heart failure...

The pharmacodynamics of spironolactone, an antimineralocorticoid and antiandrogen medication, concern its mechanisms of action, including its biological...

combination with other drugs, for the management of chronic heart failure. Spironolactone, the first member of the class, is also used in the management of hyperaldosteronism...

antagonists can also be used for treatment of primary hyperaldosteronism. Spironolactone, a steroidal aldosterone antagonist, is also used in management of female...

derived from spironolactone by the introduction of a 9α,11α-epoxy bridge and by substitution of the 17α-thoacetyl group of spironolactone with a carbomethoxy...

inhibitors finasteride and dutasteride and the steroidal AR antagonist spironolactone have been associated with significantly reduced risk of prostate cancer...

Generally, the starting dose is oral spironolactone 100 mg/day (max 400 mg/day). 40% of people will respond to spironolactone. For nonresponders, a loop diuretic...

to spironolactone which is used as a diuretic in Europe, including in Italy and Belgium. It is also an important active metabolite of spironolactone, and...

(RALES) trial is a landmark clinical study that assessed the impact of spironolactone, an aldosterone antagonist, on morbidity and mortality in patients with...

and spironolactone has mixed and inconsistent effects on hormone levels. In any case, testosterone levels are usually unchanged by spironolactone. Studies...

that have their effect at similar locations: Aldosterone antagonists: spironolactone, which is a competitive antagonist of aldosterone. Aldosterone normally...

typically with medications known as aldosterone antagonists such as spironolactone or eplerenone. Other medications for high blood pressure and a low salt...

and medications such as digitalis, methyldopa (an antihypertensive), spironolactone, certain diuretics, oxymetholone (an anabolic steroid), and chlorpromazine...

brand name Yasmin among others. The medication is an analog of the drug spironolactone. Drospirenone is taken by mouth. Common side effects include acne, headache...

steroidal antimineralocorticoid of the spirolactone group related to spironolactone that was never marketed. It is the lactonic form of mexrenoic acid (mexrenoate)...

currently available aldosterone antagonists such as eplerenone and spironolactone, which should result in fewer adverse effects like gynaecomastia, impotence...

birth control pill, spironolactone has shown a 33 to 85% reduction in acne lesions in women. The effectiveness of spironolactone for acne appears to be...

(spirolactone) SC-8109 SC-11927 (CS-1) SC-19886 SC-27169 Spirorenone Spironolactone Spiroxasone Tibolone Trimegestone Vamorolone ZK-91587 ZK-97894 Nonsteroidal:...

Promegestone Prorenone Rosterolone RU-15328 SC-5233 (spirolactone) Spironolactone Spirorenone Spiroxasone Topterone Trimegestone Trimethyltrienolone (R-2956)...

Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin Tacrolimus...

with more significant symptoms, birth control pills or the diuretic spironolactone may be useful. Over 90% of women report having some premenstrual symptoms...

chronic CSR had improved visual acuity compared to control patients. Spironolactone is a mineralocorticoid receptor antagonist that may help reduce the...

(spirolactone) SC-8109 SC-11927 (CS-1) SC-19886 SC-27169 Spirorenone Spironolactone Spiroxasone Tibolone Trimegestone Vamorolone ZK-91587 ZK-97894 Nonsteroidal:...

Promegestone Prorenone Rosterolone RU-15328 SC-5233 (spirolactone) Spironolactone Spirorenone Spiroxasone Topterone Trimegestone Trimethyltrienolone (R-2956)...

Anti-seborrheics Antiandrogens Bicalutamide Cyproterone acetate Flutamide Spironolactone Antifungals Bifonazole Cetrimonium bromide (cetrimide) Ciclopirox olamine...

Bisoprolol Digoxin Enalapril Furosemide Hydrochlorothiazide Losartan Spironolactone Complementary: Digoxinα Dopamineα Acetylsalicylic acid (aspirin) Clopidogrel...

Anti-seborrheics Antiandrogens Bicalutamide Cyproterone acetate Flutamide Spironolactone Antifungals Bifonazole Cetrimonium bromide (cetrimide) Ciclopirox olamine...

xipamide clopamide Potassium-sparing diuretics: amiloride triamterene spironolactone eplerenone In the United States, the JNC8 (Eighth Joint National Committee...

sodium loss induced by spironolactone in the urine, however this does not reduce the antihypertensive effects of spironolactone. Furthermore, antiplatelet...

producing putrescine for stabilizing their DNA. Antiandrogens, including spironolactone, cyproterone acetate, flutamide, bicalutamide, and finasteride, can...