cellular biology, the Wnt signaling pathways are a group of signal transduction pathways which begin with proteins that pass signals into a cell through...

cellular biology, paracrine signaling is a form of cell signaling, a type of cellular communication in which a cell produces a signal to induce changes in nearby...

Autocrine signaling is a form of cell signaling in which a cell secretes a hormone or chemical messenger (called the autocrine agent) that binds to autocrine...

WNT or Wnt may refer to: Windows NT WNT (Women's National Team) Wnt signaling pathway, a complex protein network The Weymouth New Testament (1902), translation...

could be attributed to Wnt signaling and that Vg1 and Wnt must cooperate to induce this process. Misexpression of Vg1 along with Wnt antagonists, Crescent...

the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and...

through a SOX-like high mobility group domain. They are involved in the Wnt signaling pathway, particularly during embryonic and stem-cell development, but...

with another family member, WNT10B, in the chromosome 12q13 region. Wnt signaling pathway GRCh38: Ensembl release 89: ENSG00000125084 – Ensembl, May 2017...

Protein Wnt-5a is a protein that in humans is encoded by the WNT5A gene. The WNT gene family consists of structurally related genes that encode secreted...

attachment and signaling. The activity of one protein in particular, beta-catenin, is controlled by the APC protein (see: Wnt signaling pathway). Regulation...

antagonist of the Wnt/β-catenin signalling pathway that acts by isolating the LRP6 co-receptor so that it cannot aid in activating the WNT signaling pathway. This...

laboratory reported a breakthrough in being able to recapitulate canonical Wnt signaling using water-soluble bispecific ligands that dimerize Frizzled and Lrp6...

collectively suggest a critical role of presenilin 1 in the Notch signaling pathway. Wnt signaling pathway has been shown to be involved in several critical steps...

BMP-induced bone formation by sclerostin is mediated by Wnt signaling, but not BMP signaling pathways. Sclerostin is expressed in osteocytes and some...

(Dsh) is a family of proteins involved in canonical and non-canonical Wnt signalling pathways. Dsh (Dvl in mammals) is a cytoplasmic phosphoprotein that...

APC, WNT signaling pathway regulator is a protein that in humans is encoded by the APC gene. This gene encodes a tumor suppressor protein that acts as...

regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion...

A biochemical cascade, also known as a signaling cascade or signaling pathway, is a series of chemical reactions that occur within a biological cell when...

Protein Wnt-3a is a protein that in humans is encoded by the WNT3A gene. The WNT gene family consists of structurally related genes that encode secreted...

function were the supramolecular complexes (Wnt signalosomes) formed by components of the Wnt signaling pathway. The Dishevelled (Dsh or Dvl) protein...

domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP1 and SFRP5 may be involved...

female to male sex reversal. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been...

function as regulators of signal transduction pathways in most eukaryotic cell types. CK1 isoforms are involved in Wnt signaling, circadian rhythms, nucleo-cytoplasmic...

negatively regulate wnt signaling by ubiquitinating frizzled receptors. Thereby, R-spondin binding to LGR5 potentiates wnt signaling. LGR5 are well-established...

The Notch signaling pathway is a highly conserved cell signaling system present in most animals. Mammals possess four different notch receptors, referred...

secretion of Wnt-7a to mossy fiber cells causes growth cone enlargement by spreading microtubules. Furthermore, Wnt-7a retrograde signaling recruits synaptic...

phosphorylation. Reduction of canonical Wnt signals upon depletion of LRP5 and LRP6 results in p120-catenin degradation. The Wnt signaling pathway was first linked to...

transducing signals by Wnt proteins through the canonical Wnt pathway. A LRP6 mutant lacking the intracellular domain is defective in Wnt signaling while LRP6...

transcription factors can have large effects on the Wnt signalling pathway. Stimulation of the Wnt signaling pathway leads to the association of β-catenin with...

female to male sex reversal. Furthermore, it promotes canonical WNT/β catenin signaling. The protein has two cysteine-rich, furin-like domains and one...