11b-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin 6-(5H)-one) Delorazepam (7-chloro-5-(o-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one) Diazepam (7-chloro-1...
53 KB (6,685 words) - 06:12, 11 June 2024
the Leuckart reaction is its use in the synthesis of tetrahydro-1,4 benzodiazepin-5-one, a molecule that is part of the benzodiazepine family. Many compounds...
6 KB (635 words) - 05:39, 24 May 2024
1-methyltriazolobenzodiazepines (alprazolam type) is possible by heating 1,4-benzodiazepin-2-thiones with hydrazine and acetic acid in n-butanol under reflux....
1 KB (107 words) - 20:56, 6 July 2023
An alternate isomer, 5-(2-bromophenyl)-7-fluoro-1,3-dihydro-2H-1,4-benzodiazepin-2-one or "iso-flubromazepam", may have been sold under the same name...
6 KB (461 words) - 18:58, 24 August 2024
June 2020. US patent 3371085, Sternbach LH, Reeder E, "5-ARYL-3H-1,4-BENZODIAZEPIN-2(1H)-ONES", published 1968-02-27, issued 1968-02-27, assigned to Hoffmann...
103 KB (10,001 words) - 13:47, 14 July 2024
"Electronic factors in the structure-activity relationship of some 1,4-benzodiazepin-2-ones". Journal of Medicinal Chemistry. 20 (9): 1206–1210. doi:10.1021/jm00219a019...
108 KB (3,088 words) - 07:42, 22 July 2024
2-dihydro-3H-1,4-benzodiazepin-2-on-4-oxide, a second reaction with acetic anhydride gives 7-chloro-1,3-dihydro-3-acetoxy-5-(2′-chlorphenyl)-2H-benzodiazepin-2-one...
5 KB (441 words) - 22:59, 4 April 2024
[1,2-a] [1,4] benzodiazepin-1-one) Lormetazepam (7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl- 2H-1,4-benzodiazepin-2-one) Midazolam...
5 KB (735 words) - 07:09, 21 June 2021
"Pharmacological studies on 1-methyl-7-nitro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one (S-1530)". Arzneimittel-Forschung. 22 (3): 534–9. PMID 5067925...
17 KB (1,803 words) - 13:39, 22 October 2023
2,4]triazolo[4,3-a] [1,4]benzodiazepin Flubromazepam 7-Brom-5-(2-fluorphenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-on Flubromazolam...
49 KB (325 words) - 11:48, 12 August 2024
prodrug to its active metabolite 7-bromo-2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one (desalkylgidazepam or bromo-nordazepam). Its anxiolytic effects...
7 KB (529 words) - 10:26, 15 July 2024
intramolecular reaction ensues, resulting in 7-bromo-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one, characterized by a seven-membered ring known as diazepine. Subsequently...
20 KB (2,075 words) - 19:30, 17 July 2024
patent 3296249, Stanley C. Bell, "5-monocyclic aryl-1, 3-dihydro-2h-1, 4-benzodiazepin-2-ones", published 1967-01-03, issued 1967-01-03, assigned to American...
80 KB (8,524 words) - 05:56, 22 August 2024
benzodiazepines, phenazepam (7-bromo-5-(2-chlorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one) is composed of a benzene ring fused to a seven-membered 1,4-diazepine...
24 KB (2,232 words) - 14:29, 24 August 2024
CD studies of optically active substituted 1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-ones". Liebigs Annalen der Chemie. 1995 (10): 1861–1869. doi:10.1002/jlac...
3 KB (195 words) - 04:26, 25 March 2024
temazepam) also known as 7-chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one Ephedrine also known as (1R,2S)-2-(methylamino)-1-phenylpropan-1-ol...
19 KB (1,748 words) - 22:01, 6 July 2024
Kidney Identifiers IUPAC name 5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-1,4-benzodiazepin-2-one CAS Number 1622-61-3 Y PubChem CID 2802 IUPHAR/BPS 6963 DrugBank...
78 KB (7,587 words) - 00:50, 19 August 2024
on 2023-08-03. Retrieved 2023-08-16. US Patent 3371085 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones Su TP, Chen TJ, Hwang SJ, Chou LF, Fan AP, Chen YC (August...
8 KB (642 words) - 18:58, 24 August 2024
heterocyclization product, 7-chloro-1,3-dihydro-3-carbethoxy-5-phenyl-2H-benzodiazepin-2-one. Upon hydrolysis using an alcoholic solution of potassium hydroxide...
18 KB (1,855 words) - 07:36, 26 June 2024
IUPAC name (RS)-7-Chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-1,4-benzodiazepin-2-one CAS Number 846-50-4 Y PubChem CID 5391 IUPHAR/BPS 7300 DrugBank...
66 KB (7,039 words) - 22:59, 18 August 2024
3-dihydro-2H-1,4-benzodiazepin-2-one (chlordesmethyldiazepam) versus 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one (lorazepam)...
18 KB (1,940 words) - 18:15, 5 August 2024
7-chloro-1-cyclopropylmethyl-1, 3-dihydro-5-(2-fluorophenyl)-2H-1, 4-benzodiazepin-2-one (KB-509) (author's transl)]". Nihon Yakurigaku Zasshi. Folia Pharmacologica...
7 KB (616 words) - 04:40, 25 March 2024
October 2022. CAS registry number:2898-08-0 1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one; other names: Ro 05-2921, dechlorodemethyldiazepam. Ripka WC,...
159 KB (16,654 words) - 05:27, 30 July 2024
Identifiers IUPAC name (RS)-7-Chloro-3-hydroxy-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one CAS Number 604-75-1 PubChem CID 4616 IUPHAR/BPS 7253 DrugBank...
30 KB (3,075 words) - 01:55, 25 May 2024
benzodiazepine, with the chemical name 1,3-Dihydro-7-nitro-5-phenyl-2H-1,4- benzodiazepin-2-one. It is long acting, lipophilic, and metabolised hepatically by...
64 KB (7,069 words) - 11:00, 25 May 2024
3-dihydro-2H-1,4-benzodiazepin-2-on (Process for the preparation of 3-N,N-dimethylcarbamoyloxy-1-methyl-5-phenyl-7-chloro-1,3-dihydro-2H-1,4-benzodiazepin-2-one)"...
13 KB (1,310 words) - 15:16, 1 February 2024
7-Chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one CAS Number 17617-23-1 Y PubChem CID 3393 IUPHAR/BPS 7188 DrugBank...
18 KB (1,659 words) - 20:32, 2 August 2024
S2CID 249382539. "ChemIDplus - 7-Bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one". chem.nlm.nih.gov. Andronati SA, Zin'kovskiĭ VG, Totrova MI,...
67 KB (8,048 words) - 00:52, 10 August 2024
10-chloro-11b-(2-chlorophenyl)-3-methyl-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one CAS Number 31868-18-5 PubChem CID 4177 ChemSpider 4033 Y UNII...
5 KB (356 words) - 13:33, 25 December 2023
-1-piperazinyl)methylene]-8-nitro-2,4-dihydro-1H-imidazo[1,2-a][1,4]benzodiazepin-1-one CAS Number 61197-73-7 N PubChem CID 3033860 DrugBank DB13643 Y...
19 KB (1,892 words) - 12:35, 5 August 2024