Fluorouracil (5-FU, 5-fluorouracil), sold under the brand name Adrucil among others, is a cytotoxic chemotherapy medication used to treat cancer. By intravenous...
31 KB (2,796 words) - 07:50, 10 August 2024
colorectal cancer, made up of the drugs folinic acid (leucovorin, FOL), fluorouracil (5-FU, F), and oxaliplatin (Eloxatin, OX). Adjuvant treatment in patients...
10 KB (1,337 words) - 04:46, 21 April 2023
survival outcomes that accompanied use of Cyclophosphamide Methotrexate Fluorouracil (CMF) after the initial mastectomy. In 1976, shortly after Bonadonna's...
40 KB (4,808 words) - 04:21, 1 July 2024
ribonucleotide formyltransferase. The fluoropyrimidines include fluorouracil and capecitabine. Fluorouracil is a nucleobase analogue that is metabolised in cells...
155 KB (17,546 words) - 07:30, 9 October 2024
symptoms. This may include salicylic acid, cryotherapy, chemo-based fluorouracil or bleomycin, and surgical removal. The skin atop the lesion should generally...
17 KB (1,657 words) - 15:04, 7 October 2024
methotrexate and pyrimethamine. It is also used in combination with 5-fluorouracil to treat colorectal cancer and pancreatic cancer, may be used to treat...
18 KB (1,572 words) - 11:23, 8 October 2024
applications, which in this context decreases the cytotoxicity of 5-fluorouracil; F – fluorouracil (5-FU), a pyrimidine analog and antimetabolite which incorporates...
4 KB (411 words) - 21:05, 6 May 2024
CMF (chemotherapy) (redirect from Cyclophosphamide methotrexate fluorouracil)
Cyclophosphamide Methotrexate Fluorouracil (CMF) is a commonly used regimen of breast cancer chemotherapy that combines three anti-cancer agents: cyclophosphamide...
3 KB (308 words) - 11:19, 15 March 2024
harm to the fetus. Capecitabine, inside the body, is converted to 5-fluorouracil (5-FU) through which it acts. It belongs to the class of medications...
14 KB (1,105 words) - 06:03, 14 September 2024
derivative that modulates/potentiates/reduces the side effects of fluorouracil; F – fluorouracil (5-FU), a pyrimidine analog and antimetabolite which incorporates...
5 KB (574 words) - 21:05, 6 May 2024
a vitamin B derivative that enhances the effects of 5-fluorouracil (5-FU); F – fluorouracil (5-FU), a pyrimidine analog and antimetabolite which incorporates...
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Actinic keratosis (section Fluorouracil cream)
by illumination with a strong light source. Topical creams, such as 5-fluorouracil or imiquimod, may require daily application to affected skin areas over...
71 KB (8,809 words) - 10:32, 18 September 2024
The Nigro protocol is the preoperative use of chemotherapy with 5-fluorouracil and mitomycin and medical radiation for squamous cell carcinomas of the...
5 KB (504 words) - 18:04, 4 October 2024
cancers. In vitro uses of floxuridine include 5-minute treatments of fluorouracil, floxuridine, and mitomycin to increase cell proliferation in Tenon's...
12 KB (1,274 words) - 06:04, 4 January 2024
Cladribine Clofarabine Cytarabine Decitabine Doxifluridine Fludarabine Fluorouracil Gemcitabine Hydroxyurea Mercaptopurine Methotrexate Nelarabine Pemetrexed...
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is generally responsive to topic chemotherapy, such as imiquimod, or fluorouracil, although surgical treatment is better able to ensure complete removal...
55 KB (5,426 words) - 02:58, 15 October 2024
small cell lung cancer. For colon cancer it is used either alone or with fluorouracil. For small cell lung cancer it is used with cisplatin. It is given intravenously...
26 KB (2,312 words) - 01:52, 17 October 2024
Tegafur is a chemotherapeutic prodrug of 5-fluorouracil (5-FU) used in the treatment of cancers. It is a component of the combination drug tegafur/uracil...
8 KB (621 words) - 12:45, 8 December 2023
condition may develop life-threatening toxicity following exposure to 5-fluorouracil (5-FU), a chemotherapy drug that is used in the treatment of cancer....
6 KB (677 words) - 22:22, 16 November 2023
medications, which include: Capecitabine Carmofur (HCFU) Doxifluridine Fluorouracil (5-FU) Tegafur Some metabolites of these drugs, such as 5-fluorodeoxyuridylate...
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retinopathy of prematurity. Aflibercept (Zaltrap), in combination with fluorouracil, leucovorin, and irinotecan (known as FOLFIRI), is indicated for the...
34 KB (2,404 words) - 18:19, 5 October 2024
reactivity can be altered significantly. For example, both uracil and 5-fluorouracil are colourless, high-melting crystalline solids, but the latter is a...
41 KB (4,534 words) - 14:34, 22 September 2024
bottled concentrated salicylic acid and lactic acid solution. Fluorouracil — Fluorouracil cream, a chemotherapy agent sometimes used to treat skin cancer...
40 KB (4,104 words) - 00:56, 21 September 2024
have been given. Biochemist Marie Hakala, PhD first observed that 5-fluorouracil becomes more effective in treating cancer cells when calcium leucovorin...
34 KB (3,124 words) - 15:16, 25 July 2024
inhibit normal function. Thymine could also be a target for actions of 5-fluorouracil (5-FU) in cancer treatment. 5-FU can be a metabolic analog of thymine...
10 KB (889 words) - 09:48, 9 August 2024
ligand), a protein Fluffy transcription factor, gene of Neurospora crassa Fluorouracil (5-FU), and leucovorin (folinic acid), a chemotherapy regimen Follicular...
2 KB (243 words) - 22:00, 22 June 2024
colorectal cancer, typically along with folinic acid (leucovorin) and fluorouracil in a combination known as FOLFOX or along with capecitabine in a combination...
19 KB (1,553 words) - 19:42, 17 May 2024
drug antimetabolites include, but are not limited to the following: 5-Fluorouracil (5-FU) 6-Mercaptopurine (6-MP) Capecitabine (Xeloda®) Cytarabine (Ara-C®)...
12 KB (1,314 words) - 05:55, 8 July 2024
studied in the 1970s. The initial regimen of cyclophosphamide and 5-fluorouracil was quickly joined by multiple regimens using a host of other systemic...
58 KB (6,264 words) - 09:37, 13 October 2024
as AC) breast cancer CAF cyclophosphamide, doxorubicin (Adriamycin), fluorouracil (5-FU) breast cancer CAPOX or XELOX capecitabine and oxaliplatin colorectal...
23 KB (634 words) - 23:47, 16 August 2024