A myokine is one of several hundred cytokines or other small proteins (~5–20 kDa) and proteoglycan peptides that are produced and released by skeletal...

that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. In addition, osteoblasts secrete...

IL-6 Cytokine and Myokine Macrophages, osteoblasts, adipocytes, and smooth muscle cells (cytokine) Skeletal muscle cells (myokine) Pro-inflammatory cytokine...

Jedrychowski MP, Korde A, Ye L, Lo JC, et al. (January 2012). "A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis"...

leading them to introduce the term "myokine". He furthered the understanding of interleukin 6 (IL-6) as a myokine, demonstrating through human infusion...

redundancy Cytokine release syndrome Cytokine secretion assay ELISA assays Myokine Signal transduction Thymic stromal lymphopoietin Virokine Saito explains...

maintains NAD+ in the hypothalamus (the control center) in conjunction with myokines from skeletal muscle cells. In 2018, Napa Therapeutics was formed to develop...

endocrine organ by secreting myokines – a wide range of cytokines and other peptides that act as signalling molecules. Myokines in turn are believed to mediate...

factor Intracrine List of investigational sex-hormonal agents Metabolomics Myokine Neohormone Neuroendocrinology Paracrine signaling Plant hormones, a.k.a...

mechanism initiated by muscular contraction, irisin has been classified as a myokine. Based on the findings that FNDC5 induces thermogenin expression in fat...

organ. That is, contracting muscles release multiple substances known as myokines which promote the growth of new tissue, tissue repair, and multiple anti-inflammatory...

with multiple beneficial effects when released by contracting muscle as a myokine. IL-6 had previously been classified as a proinflammatory cytokine. Therefore...

organ. That is, contracting muscles release multiple substances known as myokines, which promote the growth of new tissue, tissue repair, and various anti-inflammatory...

shown that both aerobic and anaerobic exercise promote the secretion of myokines, with attendant benefits including growth of new tissue, tissue repair...

Højlund K, Gygi SP, Spiegelman BM (January 2012). "A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis"...

is a protein that in humans is encoded by the MSTN gene. Myostatin is a myokine that is produced and released by myocytes and acts on muscle cells to inhibit...

Philippines, enacted in 1997 C1q/TNF related protein (CTRP) family, see Myokine. This disambiguation page lists articles associated with the title CTRP...

cardiac and vascular dysfunction with increased age. IL-10 is linked to the myokines, as exercise provokes an increase in circulating levels of IL-1ra, IL-10...

Ikeda produces a pamphlet on the benefits of exercise, such as producing Myokine which stimulate the brain and Serotonin to prevent depression. Himuro catches...

Peng; Lu, Ping; Sartini, Loris; Di Comite, Mariasevera (2015-09-29). "The myokine irisin increases cortical bone mass". Proceedings of the National Academy...

Byerly MS, Wei Z, Wong GW (April 2012). "Myonectin (CTRP15), a novel myokine that links skeletal muscle to systemic lipid homeostasis". The Journal...

during/after exercise – have also shown promising results. Exerkines include myokines. Extracellular vesicles were shown to be secreted concomitantly with exerkines...

to be associated with excessive body weight. Adipose tissue Hepatokines Myokines Mancuso P (May 2016). "The role of adipokines in chronic inflammation"...

as running, swimming, and cycling increases BDNF biosynthesis through myokine signaling, resulting in up to a threefold increase in blood plasma and...

due to its now well-established role in the secretion of myokines. The use of the term myokine to describe cytokines and other peptides produced by muscle...

mice and adult humans. In 2012, Spiegelman and colleagues discovered the myokine irisin (2012) and further demonstrated that this hormone was produced in...

Højlund, K; Gygi, SP; Spiegelman, BM (11 January 2012). "A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis"...

00170. PMC 4064707. PMID 24999318. Moreover, recent evidence suggests that myokines released by exercising muscles affect the expression of brain-derived neurotrophic...

also produced by skeletal muscle in response to different exercise doses (myokine), playing significant roles in visceral (intra-abdominal or interstitial)...

Sarcopenia and Sarcopenic Obesity. Role of Physical Exercise, Microbiota and Myokines". Cells. 11 (1): 160. doi:10.3390/cells11010160. ISSN 2073-4409. PMC 8750433...