Prostaglandins (PG) are a group of physiologically active lipid compounds called eicosanoids that have diverse hormone-like effects in animals. Prostaglandins...
24 KB (2,463 words) - 17:42, 11 July 2024
Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost is a naturally occurring prostaglandin used in medicine to induce...
12 KB (1,134 words) - 18:55, 24 April 2024
Prostaglandin E2 (PGE2), also known as dinoprostone, is a naturally occurring prostaglandin with oxytocic properties that is used as a medication. Dinoprostone...
34 KB (3,565 words) - 20:10, 14 May 2024
Cyclooxygenase (redirect from Prostaglandin-endoperoxide synthase)
Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes, EC 1.14.99.1)...
16 KB (1,779 words) - 11:08, 3 July 2024
Prostaglandin E1 (PGE1) is a naturally occurring prostaglandin and is also used as a medication (alprostadil). In infants with congenital heart defects...
13 KB (1,105 words) - 07:16, 28 May 2024
Prostaglandin analogues are a class of drugs that bind to a prostaglandin receptor. Wider use of prostaglandin analogues is limited by unwanted side effects...
3 KB (342 words) - 21:37, 11 July 2024
Prostaglandin inhibitors are drugs that inhibit the synthesis of prostaglandin in human body. There are various types of prostaglandins responsible for...
26 KB (2,117 words) - 14:49, 24 May 2024
Prostacyclin (redirect from Prostaglandin I2)
Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation...
20 KB (1,639 words) - 08:58, 22 December 2023
Prostaglandin E is a family of naturally occurring prostaglandins that are used as medications. Types include: Prostaglandin E1 also known as alprostadil...
5 KB (148 words) - 21:50, 4 March 2021
Cyclooxygenase-1 (redirect from Prostaglandin-endoperoxide synthase 1)
Cyclooxygenase 1 (COX-1), also known as prostaglandin-endoperoxide synthase 1 (HUGO PTGS1), is an enzyme that in humans is encoded by the PTGS1 gene....
18 KB (2,122 words) - 12:15, 2 June 2024
Prostaglandin G2 is an organic peroxide belonging to the family of prostaglandins. The compound has been isolated as a solid, although it is usually used...
3 KB (143 words) - 18:37, 24 April 2024
Prostaglandin D2 (or PGD2) is a prostaglandin that binds to the receptor PTGDR (DP1), as well as CRTH2 (DP2). It is a major prostaglandin produced by...
11 KB (1,090 words) - 00:21, 17 February 2024
Prostaglandin E3 (PGE3) is a naturally formed prostaglandin and is formed via the cyclooxygenase (COX) metabolism of eicosapentaenoic acid. Prostaglandin...
2 KB (55 words) - 23:51, 3 April 2023
Prostaglandin H2 (PGH2), or prostaglandin H2 (PGH2), is a type of prostaglandin and a precursor for many other biologically significant molecules. It...
6 KB (505 words) - 01:38, 1 March 2024
growths in the intestinal tract. Overexpression of COX-2 produces excess prostaglandins, which have been shown to increase the possibility of colorectal cancer...
42 KB (4,944 words) - 11:56, 4 April 2024
cyclooxygenase 1 and 2 (COX1 and COX2), thereby decreasing production of prostaglandins. Ketorolac was patented in 1976 and approved for medical use in 1989...
25 KB (2,264 words) - 23:10, 26 May 2024
Cyclooxygenase-2 (redirect from Prostaglandin-endoperoxide synthase 2)
Cyclooxygenase-2 (COX-2), also known as Prostaglandin-endoperoxide synthase 2 (HUGO PTGS2), is an enzyme that in humans is encoded by the PTGS2 gene....
30 KB (3,417 words) - 14:36, 15 May 2024
Misoprostol (category Prostaglandins)
Misoprostol is a synthetic prostaglandin medication used to prevent and treat stomach and duodenal ulcers, induce labor, cause an abortion, and treat...
51 KB (4,767 words) - 15:29, 17 July 2024
generates prostaglandin E (PGE) from prostaglandin H2. The synthase generating PGE2 is a membrane-associated protein. Humans express three prostaglandin-E synthase...
3 KB (205 words) - 15:33, 26 August 2023
enzymes are involved in the synthesis of key biological mediators, namely prostaglandins, which are involved in inflammation, and thromboxanes, which are involved...
110 KB (11,559 words) - 22:46, 13 August 2024
Prostaglandin EP3 receptor (EP3, 53kDa), is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER3; it is one of four identified...
38 KB (4,320 words) - 05:35, 12 August 2024
Prostaglandin E2 receptor 1 (EP1) is a 42kDa prostaglandin receptor encoded by the PTGER1 gene. EP1 is one of four identified EP receptors, EP1, EP2, EP3...
20 KB (2,320 words) - 00:41, 17 July 2024
in animal fats. It is a precursor in the formation of leukotrienes, prostaglandins, and thromboxanes. Together with omega-3 fatty acids and other omega-6...
21 KB (1,900 words) - 21:15, 28 July 2024
Prostaglandin E2 receptor 4 (EP4) is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the PTGER4 gene in humans; it is one of four identified...
40 KB (4,808 words) - 02:56, 28 March 2024
Aspirin (section Prostaglandins and thromboxanes)
of Surgeons in London, showed aspirin suppressed the production of prostaglandins and thromboxanes. For this discovery he was awarded the 1982 Nobel Prize...
152 KB (16,394 words) - 09:52, 24 August 2024
A prostaglandin antagonist is a hormone antagonist acting upon one or more prostaglandins, a subclass of eicosanoid compounds which function as signaling...
6 KB (768 words) - 10:51, 22 May 2024
The prostaglandin E2 (PGE2) receptors are G protein-coupled receptors that bind and are activated by prostaglandin E2. They are members of the prostaglandin...
5 KB (509 words) - 01:31, 17 December 2023
Prostaglandin E2 receptor 2, also known as EP2, is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER2: it is one of...
32 KB (3,685 words) - 02:56, 10 March 2024
swelling from inflammation. It works by inhibiting the production of prostaglandins, endogenous signaling molecules known to cause these symptoms. It does...
23 KB (2,294 words) - 14:58, 28 July 2024
antipyretic effects. It acts by inhibiting the body's production of prostaglandin. It was patented in 1967 and approved for medical use in 1980. Ketoprofen...
18 KB (1,848 words) - 13:53, 1 July 2024